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Passive chip-based droplet sorting

Patent ·
OSTI ID:1171693
An apparatus for passive sorting of microdroplets including a main flow channel, a flow stream of microdroplets in the main flow channel wherein the microdroplets have substantially the same diameter and wherein the flow stream of microdroplets includes first microdroplets having a first degree of stiffness and second microdroplets having a second degree of stiffness wherein the second degree of stiffness is different than the first degree of stiffness. A second flow channel is connected to the main flow channel for the second microdroplets having a second degree of stiffness. A separator separates the second microdroplets having a second degree of stiffness from the first microdroplets and directs the second microdroplets having a second degree of stiffness into the second flow channel.
Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-07NA27344
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Number(s):
8,969,071
Application Number:
12/938,715
OSTI ID:
1171693
Country of Publication:
United States
Language:
English

References (6)

Self-Assembly and Cross-Linking of Bionanoparticles at Liquid-Liquid Interfaces journal April 2005
Isothermal surface production and regulation for high heat flux applications utilizing porous inserts journal August 2001
Inducing and Sensing Protein–Protein Interactions in Living Cells by Selective Cross-linking journal June 2007
Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells journal March 2005
The Cross-linking of Proteins with Glutaraldehyde and its use for the preparation of immunoadsorbents journal January 1969
Metal-Mediated Self-Assembly of Protein Superstructures: Influence of Secondary Interactions on Protein Oligomerization and Aggregation journal May 2008

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