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Title: Passive chip-based droplet sorting

Patent ·
OSTI ID:1171693

An apparatus for passive sorting of microdroplets including a main flow channel, a flow stream of microdroplets in the main flow channel wherein the microdroplets have substantially the same diameter and wherein the flow stream of microdroplets includes first microdroplets having a first degree of stiffness and second microdroplets having a second degree of stiffness wherein the second degree of stiffness is different than the first degree of stiffness. A second flow channel is connected to the main flow channel for the second microdroplets having a second degree of stiffness. A separator separates the second microdroplets having a second degree of stiffness from the first microdroplets and directs the second microdroplets having a second degree of stiffness into the second flow channel.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-07NA27344
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Number(s):
8,969,071
Application Number:
12/938,715
OSTI ID:
1171693
Resource Relation:
Patent File Date: 2010 Nov 03
Country of Publication:
United States
Language:
English

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Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells journal March 2005
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The Cross-linking of Proteins with Glutaraldehyde and its use for the preparation of immunoadsorbents journal January 1969
Inducing and Sensing Protein–Protein Interactions in Living Cells by Selective Cross-linking journal June 2007
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