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Title: Microbial reductive dehalogenation of vinyl chloride

Patent ·
OSTI ID:1119695

Compositions and methods are provided that relate to the bioremediation of chlorinated ethenes, particularly the bioremediation of vinyl chloride by Dehalococcoides-like organisms. An isolated strain of bacteria, Dehalococcoides sp. strain VS, that metabolizes vinyl chloride is provided; the genetic sequence of the enzyme responsible for vinyl chloride dehalogenation; methods of assessing the capability of endogenous organisms at an environmental site to metabolize vinyl chloride; and a method of using the strains of the invention for bioremediation.

Research Organization:
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA, USA
Sponsoring Organization:
USDOE
DOE Contract Number:
FG07-99ER62883
Assignee:
The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
Patent Number(s):
8,647,824
Application Number:
13/294,927
OSTI ID:
1119695
Country of Publication:
United States
Language:
English

References (12)

Nucleic acid, nucleic acid for detecting dechlorination bacteria, probe, method for detecting dechlorination bacteria and method for treating earth or underground water polluted by chlorinated ethylene or chlorinated ethane patent October 2006
Microrna-related nucleic acids and uses thereof patent November 2009
Nucleic acid, nucleic acid for detecting dechlorination bacteria, probe, method for detecting dechlorination bacteria and method for treating earth or underground water polluted by chlorinated ethylene or chlorinated ethane patent-application September 2003
Identification and mapping of single nucleotide polymorphisms in the human genome patent-application March 2006
Growth of a Dehalococcoides-Like Microorganism on Vinyl Chloride and cis-Dichloroethene as Electron Acceptors as Determined by Competitive PCR journal February 2003
Complete Detoxification of Vinyl Chloride by an Anaerobic Enrichment Culture and Identification of the Reductively Dechlorinating Population as a Dehalococcoides Species journal February 2003
Detoxification of vinyl chloride to ethene coupled to growth of an anaerobic bacterium journal July 2003
Molecular Analysis of Dehalococcoides 16S Ribosomal DNA from Chloroethene-Contaminated Sites throughout North America and Europe journal February 2002
Trichloroethene Reductive Dehalogenase from Dehalococcoides ethenogenes: Sequence of tceA and Substrate Range Characterization journal December 2000
Isolation of a Bacterium That Reductively Dechlorinates Tetrachloroethene to Ethene journal June 1997
Reductive Dechlorination of cis -1,2-Dichloroethene and Vinyl Chloride by “ Dehalococcoides ethenogenes journal February 2001
From genes to protein structure and function: novel applications of computational approaches in the genomic era journal January 2000