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Title: SENTRA, a database of signal transduction proteins.

Journal Article · · Nucleic Acids Res.

SENTRA, available via URL http://wit.mcs.anl.gov/WIT2/Sentra/, is a database of proteins associated with microbial signal transduction. The database currently includes the classical two-component signal transduction pathway proteins and methyl-accepting chemotaxis proteins, but will be expanded to also include other classes of signal transduction systems that are modulated by phosphorylation or methylation reactions. Although the majority of database entries are from prokaryotic systems, eukaroytic proteins with bacterial-like signal transduction domains are also included. Currently SENTRA contains signal transduction proteins in 34 complete and almost completely sequenced prokaryotic genomes, as well as sequences from 243 organisms available in public databases (SWISS-PROT and EMBL). The analysis was carried out within the framework of the WIT2 system, which is designed and implemented to support genetic sequence analysis and comparative analysis of sequenced genomes.

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States)
DOE Contract Number:
DE-AC02-06CH11357
OSTI ID:
942744
Report Number(s):
ANL/MCS/JA-34180; NARHAD; TRN: US200922%%644
Journal Information:
Nucleic Acids Res., Vol. 28, Issue 1 ; Jan. 1, 2000; ISSN 0305-1048
Country of Publication:
United States
Language:
ENGLISH

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