Late injury of cancer therapy on the female reproductive tract
- Washington Univ. School of Medicine, St. FLouis, MO (United States)
- Radiological Associates, Sacramento, CA (United States)
- Fox Chase Cancer Center, Philadelphia, PA (United States); and others
The purpose of this article is to review the late effects of cancer therapy on the female reproductive tract. The anatomic sites detailed are the vulva, vagina, cervix, uterus, fallopian tubes, and ovaries. The available pathophysiology is discussed. Clinical syndromes are presented. Tolerance doses of irradiation for late effects are rarely presented in the literature and are reviewed where available. Management strategies for surgical, radiotherapeutic, and chemotherapeutic late effects are discussed. Endpoints for evaluation of therapeutic late effects have been formulated utilizing the symptons, objective, management, and analytic (SOMA) format. Late effects on the female reproductive tract from cancer therapy should be recognized and managed appropriately. A grading system for these effects is presented. Endpoints for late effects and tolls for the evaluation need to be further developed. 61 refs., 9 figs., 13 tabs.
- OSTI ID:
- 90889
- Journal Information:
- International Journal of Radiation Oncology, Biology and Physics, Vol. 31, Issue 5; Other Information: PBD: 30 Mar 1995
- Country of Publication:
- United States
- Language:
- English
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