An association between Manic-depressive illness and a pseudoautosomal DNA marker

Journal Article · Sun Nov 01 00:00:00 EST 1992 · American Journal of Human Genetics; (United States)

OSTI ID:7160316

Yoneda, Hiroshi; Sakai, Toshiaki; Ishida, Toru; Inayama, Yasuhiro; Nonomura, Yasuhiro; Kono, Yoshihiro; Asaba, Hiroyuki ^[1]

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1. Osaka Medical Center (Japan)

This article reports on the association between manic-depressive illness and a polymorphic DNA marker in the pseudoautosomal region (Xp22.32; Yp11.3). The authors studied two markers in 49 biologically unrelated patients and 119 normal controls. Probe 362A (DXYS20) identified four alleles. Frequencies of the A4 allele were significantly higher in patients than in controls. 9 refs., 1 tab.

• OSTI ID: 7160316
• Journal Information: American Journal of Human Genetics; (United States), Vol. 51:5; ISSN 0002-9297
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
HUMAN X CHROMOSOME
GENETIC MAPPING
HUMAN Y CHROMOSOME
MENTAL DISORDERS
GENE MUTATIONS
BIOLOGICAL MARKERS
CHROMOSOMES
HETEROCHROMOSOMES
HUMAN CHROMOSOMES
MAPPING
MUTATIONS
X CHROMOSOME
Y CHROMOSOME
550400* - Genetics