Lack of association between manic-depressive illness and a highly polymorphic marker from GABRA3 gene
Journal Article
·
· American Journal of Medical Genetics
- Universidad Autonoma de Madrid (Spain)
- Universidad de Santiago de Compostela, La Coruna (Spain); and others
We have carried out an association study between a dinucleotide repeat polymorphism in GABRA3 gene and manic-depressive illness in a Spanish population. This may be an important candidate gene for bipolar affective disorders since it is located in the Xq28 region, previously implicated in linkage studies. In addition, severe GABergic alterations have been reported in patients. We have not found significant differences between controls and patients in allele frequencies or genotypes. 9 refs., 1 tab.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 254388
- Journal Information:
- American Journal of Medical Genetics, Journal Name: American Journal of Medical Genetics Journal Issue: 5 Vol. 60; ISSN 0148-7299; ISSN AJMGDA
- Country of Publication:
- United States
- Language:
- English
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