Effect of cadmium on protein synthesis in gill tissue of marine mollusc Mytilus edulis

Conference · Thu Sep 01 00:00:00 EDT 1988 · Preprints of Papers Presented at National Meeting, Division of Water, Air and Waste Chemistry, American Chemical Society; (USA)

OSTI ID:7018132

Veldhuizen-Tsoerkan, M B; van der Mast, C A; Zandee, D I ^[1]

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1. Univ. of Utrecht (Netherlands)

Mussels have a high capacity to accumulate cadmium and other heavy metals without notable toxic effects. However, they have recently found that cadmium is toxic to M. edulis at a relatively low concentration, as anoxic survival time of the animals was significantly shortened after two weeks of exposure to 50 ppb Cd. Based on this finding, a research was started to study the toxic effects of cadmium at a macromolecular level (proteins, RNA). Mussels were exposed to 250 ppb Cd for short periods. Then excised gills were incubated with {sup 35}s-methionine for 4 hours. In the gill tissue of 7 and 15 days Cd-exposed animals, a significantly decrease in the incorporation rate of the introduced label was found of 30 and 37%, respectively. Two-dimensional gel electrophoresis was used to analyze the de novo synthesized gill tissue proteins.

• OSTI ID: 7018132
• Report Number(s): CONF-8909236-; CODEN: ACWCA; TRN: 90-007858
• Journal Information: Preprints of Papers Presented at National Meeting, Division of Water, Air and Waste Chemistry, American Chemical Society; (USA), Vol. 28:2; Conference: JAERI/EPA workshop on residual radiation and recycle criteria, St. Michaels, MD (USA), 27-28 Sep 1989; ISSN 0099-7293
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
CADMIUM
TOXICITY
PROTEINS
BIOSYNTHESIS
ANOXIA
GILLS
METHIONINE
SULFUR 35
SURVIVAL TIME
TRACER TECHNIQUES
TWO-DIMENSIONAL ELECTROPHORESIS
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CARBOXYLIC ACIDS
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTROPHORESIS
ELEMENTS
EVEN-ODD NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
LIGHT NUCLEI
LIPOTROPIC FACTORS
METALS
NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
RADIOISOTOPES
RESPIRATORY SYSTEM
SULFUR ISOTOPES
SYNTHESIS
560300* - Chemicals Metabolism & Toxicology
550501 - Metabolism- Tracer Techniques