Asbestos exposure and gastrointestinal malignancy review and meta-analysis

Technical Report · Fri Jan 01 00:00:00 EST 1988

OSTI ID:6936939

Frumkin, H; Berlin, J

The epidemiologic literature linking asbestos exposure with gastrointestinal malignancy is reviewed. Problems in comparing studies are discussed, appropriate strategies for comparison are developed, and study results are pooled using a model which accounts for both intrastudy and interstudy variability. Stratification of cohorts by dose reveals that significant asbestos exposure, as indicated by a lung cancer standardized mortality ratio (SMR) of at least 200, is associated with an elevated gastrointestinal cancer SMR for five or six end points examined.

• Research Organization: Harvard Univ., Boston, MA (USA). School of Public Health
• OSTI ID: 6936939
• Report Number(s): PB-90-232216/XAB
• Resource Relation: Other Information: Pub. in American Jnl. of Industrial Medicine, Vol. 14, 79-95(Jun 1988)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ASBESTOS
CARCINOGENESIS
GASTROINTESTINAL TRACT
NEOPLASMS
EPIDEMIOLOGY
MAN
MORTALITY
OCCUPATIONAL EXPOSURE
TABLES
ANIMALS
DIGESTIVE SYSTEM
DISEASES
MAMMALS
PATHOGENESIS
PRIMATES
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology