Xe-133 rCBF measurement reproducibility and normal limits of asymmetry
New software for determination of regional cerebral blood flow (rCBF) has been added to equipment using Xe-133 inhalation and 32 p-m tubes in a helmet-like configuration (NOVO Cerebrograph 32c). The authors examined the reproducibility of rCBF measurements and the degree of asymmetry acceptable as normal. The 2 parameters studied were initial slope index (ISI) and CBF15, both heavily weighted toward the fast clearing compartment (largely grey matter) and relatively free of slow compartment (blurring). In 3 normal volunteers and 7 patients with non-focal stable neurologic disease ISI and CBF15 repeated within 24 hours could vary by as much as 18% and 29-33% respectively (2 s.d. limits) in stable individuals with no focal disease. In 7 patients with documented stable cerebrovascular disease, reproducibility for ISI was 19-22%, CBF15 22-23%, independent of age.
- Research Organization:
- Veterans Administration Medical Center, Cincinnati, OH
- OSTI ID:
- 6700909
- Report Number(s):
- CONF-850611-
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CEREBRUM
ASYMMETRY
BLOOD FLOW
VASCULAR DISEASES
DIAGNOSIS
XENON 133
DIAGNOSTIC USES
INHALATION
COMPUTER CODES
DIAGNOSTIC TECHNIQUES
IMAGES
MEASURING METHODS
PATIENTS
TRACER TECHNIQUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
DAYS LIVING RADIOISOTOPES
DISEASES
EVEN-ODD NUCLEI
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
NERVOUS SYSTEM
NUCLEI
ORGANS
RADIOISOTOPES
USES
XENON ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics