CBF before and after extracranial-intracranial bypass surgery in patients with ischemic cerebrovascular disease studied with /sup 133/Xe-inhalation tomography

Journal Article · Mon Jul 01 04:00:00 EDT 1985 · Stroke; (United States)

OSTI ID:5020380

Vorstrup, S; Lassen, N A; Henriksen, L; Haase, J; Lindewald, H; Boysen, G; Paulson, O B

Cerebral blood flow (CBF) was studied by /sup 133/Xenon inhalation tomography in 22 patients with symptoms of ischemic cerebrovascular disease before and after establishment of an extracranial-intracranial bypass shunt. Selection of patients for shunting was based on angiographically demonstrated arterial occlusions and on the finding of focal low flow areas corresponding to the clinical symptoms, that consisted mainly of minor stroke with good remission and with or without subsequent TIAs. It was required that the area of low flow should clearly exceed the CT lesion present in practically all cases. Following surgery, the permanent neurologic deficits remained unchanged, while the TIAs stopped in all but one case. Two patients showed a definite increase of CBF in the low flow area while another two showed a questionable increase. All the other cases, 18 of the 22, showed an unchanged tomographic flow map with no trend towards diminution in extension or severity of the focal hypoperfused area. A persistent low flow in areas with no corresponding CT lesion following alleviation of a possible flow impediment is interpreted to represent an incomplete infarction or diaschisis.

• Research Organization: Rigshospitalet, Copenhagen, Denmark
• OSTI ID: 5020380
• Journal Information: Stroke; (United States), Journal Name: Stroke; (United States) Vol. 4; ISSN SJCCA
• Country of Publication: United States
• Language: English

Related Subjects

550600* -- Medicine
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CARDIOVASCULAR DISEASES
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISCHEMIA
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NERVOUS SYSTEM
NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
SURGERY
TOMOGRAPHY
VASCULAR DISEASES
XENON 133
XENON ISOTOPES