Latent period in clinical radiation myelopathy

Journal Article · Sun Jul 01 00:00:00 EDT 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(84)90184-6· OSTI ID:6596860

Schultheiss, T E; Higgins, E M; El-Mahdi, A M

Seventy-seven papers containing data on more than 300 cases of radiation myelopathy have been analyzed. The data suggest that the latent periods are similar in the cervical and thoracic levels of the spinal cord and are bimodally distributed. Myelopathy of lumbar cord apparently has a shorter latent period. As in controlled animal experiments, the latent period decreases with increasing dose. Furthermore, the variation in latent periods also decreases with dose. It is also seen that retreated patients and pediatric or adolescent patients have greatly reduced latent periods. The implications of these findings as they compare with the animal data are discussed.

• Research Organization: Eastern Virginia Medical School, Norfolk
• OSTI ID: 6596860
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:7
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
NERVOUS SYSTEM DISEASES
LATENCY PERIOD
RADIOINDUCTION
REVIEWS
SPINAL CORD
DELAYED RADIATION EFFECTS
CHILDREN
PATIENTS
AGE GROUPS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CENTRAL NERVOUS SYSTEM
DISEASES
DOCUMENT TYPES
NERVOUS SYSTEM
RADIATION EFFECTS
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)