Characterization of the fluorescence spectra produced by excimer laser irradiation of the cornea

Journal Article · Wed Aug 01 00:00:00 EDT 1990 · Investigative Ophthalmology and Visual Science; (USA)

OSTI ID:6516447

Tuft, S; al-Dhahir, R; Dyer, P; Zhu, Z H ^[1]

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1. Moorfields Eye Hospital, London (England)

The epithelium and stroma of bovine and human corneas were exposed to both ablative and subablative levels of 193-nm excimer laser radiation and the spectra of the induced fluorescence recorded. Two broad peaks in the emission spectra were observed, at 310 nm and 460 nm, with a difference in the relative height of these peaks between epithelium and stroma. The lower cut-off for fluorescence (260 nm) was similar for both tissues. Time-resolved measurements showed that fluorescence occurs on the nanosecond time scale, and an estimate gives the quantum yield for photons emitted in the 260-350-nm range as approximately 1 X 10(-5). The significance of these results in the evaluation of the safety of surgery with an argon fluoride excimer laser is discussed.

• OSTI ID: 6516447
• Journal Information: Investigative Ophthalmology and Visual Science; (USA), Vol. 31:8; ISSN 0146-0404
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
CORNEA
SENSITIVITY
LASER RADIATION
BIOLOGICAL EFFECTS
CATTLE
EPITHELIUM
EXCIMER LASERS
FLUORESCENCE
MAN
PHOTONS
SURGERY
ANIMAL TISSUES
ANIMALS
BODY
BODY AREAS
DOMESTIC ANIMALS
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
EYES
FACE
GAS LASERS
HEAD
LASERS
LUMINESCENCE
MAMMALS
MASSLESS PARTICLES
MEDICINE
ORGANS
PRIMATES
RADIATIONS
RUMINANTS
SENSE ORGANS
TISSUES
VERTEBRATES
560400* - Other Environmental Pollutant Effects
550600 - Medicine