Far-ultraviolet laser ablation of the cornea: photoacoustic studies
Wide bandwidth piezoelectric transducers made of thin (9 microns) polyvinylidene fluoride film have been used to make time-resolved measurements of the stress-wave generated by far-ultraviolet (193 nm) laser ablation in corneal tissue in vitro. At high fluence (approximately 250 mJ/cm2), ablation commences within 10 ns (+/- 5 ns) of the laser pulse and generates short acoustic impulses (approximately 30 ns). The time profile of the ablation, when coupled to the energy requirements for ablation from earlier work, allows the estimation of a temperature and a half-life for the thermal decomposition of the collagen in cornea. These values do not support a photothermal mechanism for the ablation under the experimental conditions.
- Research Organization:
- IBM T.J. Watson Research Center, Yorktown Heights, NY
- OSTI ID:
- 6497518
- Journal Information:
- Lasers Surg. Med.; (United States), Vol. 6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
COLLAGEN
THERMAL DEGRADATION
CORNEA
SURGERY
BIOLOGICAL RADIATION EFFECTS
LASERS
RABBITS
ULTRAVIOLET RADIATION
ANIMALS
BIOLOGICAL EFFECTS
BODY
BODY AREAS
ELECTROMAGNETIC RADIATION
EYES
FACE
HEAD
MAMMALS
MEDICINE
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIATION EFFECTS
RADIATIONS
SCLEROPROTEINS
SENSE ORGANS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals
550600 - Medicine