Interaction of ultraviolet laser light with the cornea
The effect of pulsed ultraviolet (UV) laser light on the cornea depends on wavelength (photon energy), irradiance (photon flux), and pulse firing rate. At the available excimer laser wavelengths of 193, 249, 308, and 351 nanometers, the authors have varied the irradiance per pulse (10 to 2000 mj/cmS) as well a pulse frequency (1, 10, 25 Hz) and determined the thresholds for coagulation and ablation of the corneal stroma. The latter ablative action creates a groove resembling an incision and was present at all wavelengths studied. The threshold for ablation increased for longer wavelengths and lower pulse frequencies, except for 193-nm exposure, which was characterized by a constant threshold independent of laser pulse rate. The grooves at 193 nm were both biomicroscopically and histologically smooth and no coagulation effects were noted. Some degree of coagulation of adjacent tissues was noted at 249, 308, and 351 nm.
- Research Organization:
- Columbia Univ., New York, NY
- OSTI ID:
- 6036853
- Journal Information:
- Invest. Ophthalmol. Visual Sci.; (United States), Journal Name: Invest. Ophthalmol. Visual Sci.; (United States) Vol. 11; ISSN IOVSD
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BODY
BODY AREAS
CATTLE
CORNEA
DOMESTIC ANIMALS
ELECTROMAGNETIC RADIATION
EPITHELIUM
EYES
FACE
FLOCCULATION
HEAD
LASERS
MAMMALS
ORGANS
PRECIPITATION
RADIATIONS
RUMINANTS
SENSE ORGANS
SEPARATION PROCESSES
TISSUES
ULTRAVIOLET RADIATION
VERTEBRATES