Spectrally encoded confocal microscopy

Journal Article · Sat Aug 01 00:00:00 EDT 1998 · Optics Letters

DOI:https://doi.org/10.1364/OL.23.001152· OSTI ID:639074

Tearney, G J; Webb, R H; Bouma, B E ^[1]

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1. Wellman Laboratories of Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 703, Boston, Massachusetts 02114 (United States)

An endoscope-compatible, submicrometer-resolution scanning confocal microscopy imaging system is presented. This approach, spectrally encoded confocal microscopy (SECM), uses a quasi-monochromatic light source and a transmission diffraction grating to detect the reflectivity simultaneously at multiple points along a transverse line within the sample. Since this method does not require fast spatial scanning within the probe, the equipment can be miniaturized and incorporated into a catheter or endoscope. Confocal images of an electron microscope grid were acquired with SECM to demonstrate the feasibility of this technique. {copyright} {ital 1998} {ital Optical Society of America}

• DOE Contract Number: FG02-91ER61229
• OSTI ID: 639074
• Journal Information: Optics Letters, Vol. 23, Issue 15; Other Information: PBD: Aug 1998
• Country of Publication: United States
• Language: English

Related Subjects

66 PHYSICS
OPTICAL MICROSCOPY
MEDICAL SURVEILLANCE
SCANNING LIGHT MICROSCOPY
DIFFRACTION GRATINGS
FIBER OPTICS
REMOTE MULTIPLEXING SYSTEMS
MINIATURIZATION