Sequential hemi-body irradiation (HBI) in treatment of advanced neuroblastoma: a pilot study

Journal Article · Wed Apr 01 00:00:00 EST 1981 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(81)90139-5· OSTI ID:6231983

Helson, L; Jereb, B; Vogel, R

Eight patients between 13 months and 15 years old with Stage IV neuroblastoma were treated between December, 1978 and March, 1980 with half body irradiation in addition to multidrug chemotherapy. Three patients had HBI after completion of treatment. Five patients had HBI concomitantly with chemotherapy, of these 4 are alive. The mean survival time of the patients who died is 15 months, 2 patients are alive with disease at 18 and 25 months and 2 are disease free at 16 and 19 months from diagnosis. The main side effect of treatment was bone marrow depression. HBI did not significantly increase the toxicity produced by chemotherapy.

• Research Organization: Memorial Sloan-Kettering Cancer Center, New York, NY
• OSTI ID: 6231983
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 7:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
BONE MARROW
BIOLOGICAL RADIATION EFFECTS
NEOPLASMS
RADIOTHERAPY
NERVE TISSUE
SIDE EFFECTS
CHEMOTHERAPY
INFANTS
PARTIAL BODY IRRADIATION
PATIENTS
RADIOSENSITIVITY
SURVIVAL CURVES
TIME DEPENDENCE
AGE GROUPS
ANIMAL TISSUES
BIOLOGICAL EFFECTS
BODY
CHILDREN
DISEASES
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
IRRADIATION
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
THERAPY
TISSUES
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)