Fate of the isoprenoid hydrocarbon, pristane, in rainbow trout
The excretion routes and tissue distribution of (/sup 3/H)pristane were measured in rainbow trout, Salmo gairdneri, after a single intragastric dose (0.1 mg). This branched-alkane was quickly and largely absorbed. The balance study showed that the major routes of excretion were fecal (40.4% of the dose) and branchial (39.6%). In feces radioactivity was exclusively due to (/sup 3/H)pristane, whereas /sup 3/H resulting from gill excretion was principally associated with tritiated water. Only 2.6% of the radioactivity was cleared via the kidneys and found in the urine as metabolites. After 48 hr, no hydrocarbon accumulation was observed in gall bladder, while in liver and fat, respectively, 69 and 34% of the radioactivity originated from pristane, the rest of the labeling being mostly associated with lipid components.
- Research Organization:
- Laboratoire de Recherches sur les Additifs Alimentaires, Toulouse, France
- OSTI ID:
- 6120315
- Journal Information:
- Ecotoxicol. Environ. Saf.; (United States), Vol. 13:3
- Country of Publication:
- United States
- Language:
- English
Similar Records
Cadmium inhibition of Ca sup 2+ uptake in rainbow trout gills
Na/sup +/:K/sup +/- and HCO/sub 3//sup -/-stimulated ATPase activities in the gills and kidneys of thermally acclimated rainbow trout, Salmo gairdneri
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
ALKANES
METABOLISM
TISSUE DISTRIBUTION
TROUT
CONTAMINATION
CARCINOGENS
EXCRETION
FECES
LIPIDS
LUBRICATING OILS
TRACER TECHNIQUES
TRITIUM COMPOUNDS
WATER POLLUTION
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
CLEARANCE
DISTRIBUTION
FISHES
HYDROCARBONS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LUBRICANTS
MATERIALS
OILS
ORGANIC COMPOUNDS
OTHER ORGANIC COMPOUNDS
PETROLEUM PRODUCTS
POLLUTION
VERTEBRATES
WASTES
560300* - Chemicals Metabolism & Toxicology
550501 - Metabolism- Tracer Techniques