Nuclear magnetic resonance imaging of induced renal lesions

Journal Article · Fri Jul 01 00:00:00 EDT 1983 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.148.1.6856828· OSTI ID:5821665

London, D A; Davis, P L; Williams, R D; Crooks, L E; Sheldon, P E; Gooding, C A

Nuclear magnetic resonance (NMR) images obtained after unilateral ligation of the ureter, renal artery, or renal vein in the rat were analyzed and compared with NMR images of the normal rat kidney. Anatomic and functional correlation of the induced renal lesions was made by concurrent CT and by gross examination of the excised kidneys. Many normal anatomic structures at the level of the renal hilum can be identified by high resolution NMR imaging. Differentiation of urine from renal parenchyma permits detection of gross changes both in renal function and in the mass of the renal parenchyma. NMR imaging is capable of diagnosing hydronephrosis, acute renal ischemia, and acute venous congestion in this rat model. In addition, a trend toward prolongation of the relaxation times T1 and T2 for abnormal renal parenchyma is demonstrated.

• Research Organization: Univ. of California Medical Center, San Francisco
• OSTI ID: 5821665
• Journal Information: Radiology; (United States), Vol. 148:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
KIDNEYS
COMPUTERIZED TOMOGRAPHY
NUCLEAR MAGNETIC RESONANCE
NEPHROSCLEROSIS
DIAGNOSIS
ARTERIES
ISCHEMIA
RATS
SPIN ECHO
VEINS
ANIMALS
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DIAGNOSTIC TECHNIQUES
DISEASES
MAGNETIC RESONANCE
MAMMALS
ORGANS
RESONANCE
RODENTS
TOMOGRAPHY
UROGENITAL SYSTEM DISEASES
VASCULAR DISEASES
VERTEBRATES
550600* - Medicine
550900 - Pathology