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Title: Effect of. beta. -endorphin on catecholamine levels in rat hypothalamus and cerebral cortex

Journal Article · · Bull. Exp. Biol. Med. (Engl. Transl.); (United States)
DOI:https://doi.org/10.1007/BF00835877· OSTI ID:5784870

The authors studied the effect of beta-endorphin on catecholamine concentrations in the hypothalmus and cerebral cortex in rats, as a contribution to the explanation of the mechanism of action of this peptide on certain pituitary trophic functions. Concentrations of dopamine, noradrenalin, and adrenalin were determined by a radioenzymatic method. A Mark 3 scintillation system was used for radiometric investigation of the samples. The results of these experiments indicate that beta-endorphin has a marked effect on brain catecholamine levels mainly in the hypothalamus.

Research Organization:
Kiev Scientific-Research Institute of Endocrinology and Metabolism, USSR
OSTI ID:
5784870
Journal Information:
Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Vol. 101:5; Other Information: Translated from Byulleten Ehksperimental'noj Biologii i Meditsiny; 101: No. 5, 562-564(May 1986)
Country of Publication:
United States
Language:
English