Action of the. beta. /sub 2/-blocker propranolol on lymphocyte adrenergic receptors in essential hypertension

Journal Article · Mon Dec 01 00:00:00 EST 1986 · Bull. Exp. Biol. Med. (Engl. Transl.); (United States)

DOI:https://doi.org/10.1007/BF00839993· OSTI ID:5779695

Krasnikova, T L; Radyukhin, V A; Parfenova, E V; Suvorov, Yu I; Ustinova, S E; Shkhvatsabaya, I K

The characteristics of lymphocyte ..beta../sub 2/-adrenoreceptors in patients with essential hypertension were studied in this paper after a short course of propranolol monotherapy. The density of ..beta../sub 2/-adrenoreceptors on intact lymphocytes was determined in three patients with the use of /sup 3/H-dihydroalprenolol, in the rest with /sup 125/I-cyanopindolol. Specific binding of /sup 125/I-CIP with intact cells, like that of /sup 3/H-DHA, was characterized by high affinity and saturation.

• Research Organization: All-Union Cardiologic Scientific Center, Moscow, USSR
• OSTI ID: 5779695
• Journal Information: Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Vol. 102:7; Other Information: Translated from Byulleten' Ehksperimental'noj Biologii i Meditsiny; 102: No. 7, 46-48(Jul 1986)
• Country of Publication: United States
• Language: English

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