Intraperitoneal P-32 after negative second-look laparotomy in ovarian carcinoma

Journal Article · Thu Jun 15 00:00:00 EDT 1989 · Cancer (Philadelphia); (United States)

DOI:https://doi.org/10.1002/1097-0142(19890615)63:12<2434::AID-CNCR2820631211>3.0.CO;2-B· OSTI ID:5765983

Spencer, Jr, T R; Marks, Jr, R D; Fenn, J O; Jenrette, J.M. 3d.; Lutz, M H

Thirty-one patients underwent a negative second-look laparotomy between 1976 and 1986. Fourteen patients received intraperitoneal chromic phosphate (P-32) after a negative second-look laparotomy. There has been no local recurrence (zero of 14) and no deaths attributable to recurrent disease. Local control and disease-free survival are 100%, with a minimum follow-up of 2 years and a mean follow-up of 4 years. Seventeen patients received no further therapy because of patient refusal, poor diffusion, or other contraindications to P-32 installation. Four of 17 patients undergoing negative second-look procedures without the addition of P-32 have subsequently recurred. This difference is highly suggestive (P = .076). There have been no major complications with the addition of P-32. The use of intraperitoneal P-32 after negative second-look laparotomies on ovarian carcinoma is well tolerated and effective in preventing recurrence.

• Research Organization: Medical Univ. of South Carolina, Charleston (USA)
• OSTI ID: 5765983
• Journal Information: Cancer (Philadelphia); (United States), Vol. 63:12
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
RADIOTHERAPY
OVARIES
PATIENTS
PHOSPHORUS 32
SURGERY
SURVIVAL CURVES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
FEMALE GENITALS
GONADS
ISOTOPES
LIGHT NUCLEI
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PHOSPHORUS ISOTOPES
RADIOISOTOPES
RADIOLOGY
THERAPY
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