Tracer for circulation determinations
An improved tracer particle is described comprising an ion exchange core having a polymer coating thereon, the coated ion exchange core having a reaction site capable of reacting with a compound containing an oxirane group, said coated ion exchange core having been treated with a compound containing an oxirane group to react with said coated ion exchange core causing an increase in mass of the tracer particle. Preferably, the ion exchange core is labelled with a radionuclide. These particles have improved characteristics including improved stability against leaching and improved handling properties. Such particles are useful in circulatory determinations involving the injection of the particles as a suspension in a physiologically acceptable carrier or medium into the circulatory system of animals.
- Assignee:
- E. I. Du Pont de Nemours and Co.
- Patent Number(s):
- US 4505888
- Application Number:
- TRN: 85-019403
- OSTI ID:
- 5370451
- Resource Relation:
- Patent File Date: Filed date 27 May 1983; Other Information: PAT-APPL-498867
- Country of Publication:
- United States
- Language:
- English
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