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Title: Liver cysts in autosomal-dominant polycystic kidney disease: clinical and computed tomographic study

Hepatic CT findings were analyzed in 44 patients with autosomal-dominant polycystic kidney disease and were correlated with liver and renal function tests and liver, splenic, and renal CT volume measurements. CT showed many large liver cysts in 31.8% of patients, small liver cysts in 25%, and no liver cysts in 43.2%. Patients with many large cysts often showed increased liver volumes. There was no correlation between severity of liver involvement and extent of renal cystic disease as determined from urea nitrogen and creatinine levels and renal volumes. Liver function tests were normal except in two patients, one with a cholangiocarcinoma, which may have arisen from a cyst, and the other with an infected liver cyst and chronic active hepatitis. Accordingly, if liver function tests are abnormal, an attempt should be made to identify complications of polycystic liver disease such as tumor cyst infection, and biliary obstruction. CT is a useful method for detecting liver cysts and identifying patients at risk for these complications.
Authors:
; ;
Publication Date:
OSTI Identifier:
5149955
Report Number(s):
CONF-860416-
Journal ID: CODEN: AAJRD; TRN: 85-023784
Resource Type:
Conference
Resource Relation:
Journal Name: AJR, Am. J. Roentgenol.; (United States); Journal Volume: 145:2; Conference: ARRS meeting, Washington, DC, USA, 14 Apr 1986
Research Org:
Univ. of Kansas College of Health Sciences, Kansas City
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; KIDNEYS; HEREDITARY DISEASES; LIVER; ABSCESSES; BIOLOGICAL FUNCTIONS; COMPUTERIZED TOMOGRAPHY; UROGENITAL SYSTEM DISEASES; DIAGNOSIS; BILIARY TRACT; NEOPLASMS; PATIENTS; VOLUME; BODY; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; FUNCTIONS; GLANDS; ORGANS; PATHOLOGICAL CHANGES; TOMOGRAPHY 550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)