High-density renal cysts in autosomal dominant polycystic kidney disease demonstrated by CT
Unenhanced abdominal CT scans of 35 patients with autosomal dominant polycystic kidney disease (ADPKD) showed multiple high-density (58-84 HU) renal cysts in 42.9% of patients, occasional high-density cysts in 25.7%, and no high-density cysts in 31.4%. These high-density cysts were usually subcapsular and were more frequent in patients with markedly enlarged kidneys and flank pain at the time of CT. Follow-up CT often showed a reduction in cyst densities, although some cysts developed mural calcification and calcification of their contents. Renal carcinomas occur rarely in ADPKD and may occasionally be hyperdense. However, high-density cysts may usually be distinguished from carcinomas on CT by their smooth contours, sharp interfaces with renal parenchyma, homogeneity, and lack of contrast enhancement.
- Research Organization:
- Univ. of Kansas College of Health Sciences, Kansas City
- OSTI ID:
- 5752105
- Report Number(s):
- CONF-841170-
- Journal Information:
- Radiology; (United States), Journal Name: Radiology; (United States) Vol. 154:2; ISSN RADLA
- Country of Publication:
- United States
- Language:
- English
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550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
CARCINOMAS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
HEREDITARY DISEASES
KIDNEYS
NEOPLASMS
ORGANS
PATHOLOGY
PATIENTS
TOMOGRAPHY