High sensitivity and high Q-factor nanoslotted parallel quadrabeam photonic crystal cavity for real-time and label-free sensing

Journal Article · Mon Aug 11 00:00:00 EDT 2014 · Applied Physics Letters

DOI:https://doi.org/10.1063/1.4867254· OSTI ID:22318019

Yang, Daquan ^[1]; Kita, Shota; Wang, Cheng; Lončar, Marko ^[2]; Liang, Feng; Quan, Qimin ^[1]; Tian, Huiping; Ji, Yuefeng ^[3]

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1. Rowland Institute at Harvard University, Cambridge, Massachusetts 02142 (United States)
2. School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138 (United States)
3. State Key Laboratory of Information Photonics and Optical Communications, School of Information and Communication Engineering, Beijing University of Posts and Telecommunications, Beijing 100876 (China)

We experimentally demonstrate a label-free sensor based on nanoslotted parallel quadrabeam photonic crystal cavity (NPQC). The NPQC possesses both high sensitivity and high Q-factor. We achieved sensitivity (S) of 451 nm/refractive index unit and Q-factor >7000 in water at telecom wavelength range, featuring a sensor figure of merit >2000, an order of magnitude improvement over the previous photonic crystal sensors. In addition, we measured the streptavidin-biotin binding affinity and detected 10 ag/mL concentrated streptavidin in the phosphate buffered saline solution.

• OSTI ID: 22318019
• Journal Information: Applied Physics Letters, Vol. 105, Issue 6; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6951
• Country of Publication: United States
• Language: English

Related Subjects

71 CLASSICAL AND QUANTUM MECHANICS
GENERAL PHYSICS
BIOTIN
CRYSTALS
NANOSTRUCTURES
PERFORMANCE
PHOSPHATES
REFRACTIVE INDEX
SENSORS