Sacroplasty for Local or Massive Localization of Multiple Myeloma

Journal Article · Wed Dec 15 00:00:00 EST 2010 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-009-9761-X· OSTI ID:21428900

Basile, Antonio ^[1]; Tsetis, Dimitrios ^[2]; Cavalli, Maide; Fiumara, Paolo; Raimondo, Francesco Di ^[3]; Coppolino, Francesco ^[4]; Coppolino, Carmelo ^[1]; Mundo, Elena ^[5]; Desiderio, Carla ^[1]; Granata, Antonio ^[6]; Patti, Maria Teresa ^[1]

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1. Ospedale Ferrarotto, via Citelli 6, Department of Diagnostic and Interventional Radiology (Italy)
2. Medical School of Crete, Department of Radiology, University Hospital of Heraklion (Greece)
3. Ospedale Ferrarotto, via Citelli 6, Department of Haematology (Italy)
4. Policlinico P. Giaccone, Department of Radiology (Italy)
5. Ospedale Garibaldi, Department of Radiology (Italy)
6. Ospedale Vittorio Emanuele, via Plebiscito 125, Department of Nephrology (Italy)

The purpose of this study was to assess the efficacy of cementoplasty in the treatment of sacral multiple myelomas. We retrospectively reviewed the records of eight patients (four women and four men; age range 47-68 years; mean age 57.8) who underwent cementoplasty for painful osteolytic localization of multiple myeloma between April 2007 and May 2009. The patients had difficulty walking because of increasing pain. Six patients had persistent pain despite other cementoplasties for vertebral and femoral localization, whereas two patients referred at the time of diagnosis had only sacral lesions. The clinical indication for treatment was (1) a pain intensity score {>=}5 on visual analogue scale (VAS) and (2) pain totally or partially refractory to analgesic treatment in patients with a life expectancy >3 months. Technical planning was based on computed tomography and/or magnetic resonance imaging. Six patients had previously undergone radiotherapy or chemotherapy and were receiving varying doses of analgesics, whereas sacroplasty represented the first treatment for two patients. Five patients had monolateral local involvement, and the other patients had massive involvement of the sacrum; Technical success was achieved in all cases. We had only one small and asymptomatic foraminal leak. All patients experienced improvement in symptoms after the procedure, as demonstrated by improved VAS scores and performance status (PS) and decreased analgesic dose constant during follow-up. In our experience, percutaneous stabilization can be used effectively and safely in patients with focal or extensive involvement of the sacrum by multiple myeloma.

• OSTI ID: 21428900
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 33, Issue 6; Other Information: DOI: 10.1007/s00270-009-9761-x; Copyright (c) 2010 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ANALGESICS
CEMENTS
COMPUTERIZED TOMOGRAPHY
INJECTION
NEOPLASMS
NMR IMAGING
PAIN
PLASMA CELLS
VERTEBRAE
ANIMAL CELLS
BODY
BUILDING MATERIALS
CENTRAL NERVOUS SYSTEM AGENTS
CENTRAL NERVOUS SYSTEM DEPRESSANTS
CONNECTIVE TISSUE CELLS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
INTAKE
MATERIALS
ORGANS
SKELETON
SOMATIC CELLS
SYMPTOMS
TOMOGRAPHY