Increasing cell culture population doublings for long-term growth of finite life span human cell cultures
Patent
·
OSTI ID:1171090
Cell culture media formulations for culturing human epithelial cells are herein described. Also described are methods of increasing population doublings in a cell culture of finite life span human epithelial cells and prolonging the life span of human cell cultures. Using the cell culture media disclosed alone and in combination with addition to the cell culture of a compound associated with anti-stress activity achieves extended growth of pre-stasis cells and increased population doublings and life span in human epithelial cell cultures.
- Research Organization:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC02-05CH11231
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Number(s):
- 8,962,325
- Application Number:
- 12/242,474
- OSTI ID:
- 1171090
- Resource Relation:
- Patent File Date: 2008 Sep 30
- Country of Publication:
- United States
- Language:
- English
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