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Title: Development of MAG3 p-nitrophenyl ester for technetium-99m and rhenium-188 labeling of amines and peptides

Conference ·
OSTI ID:10184756
; ;  [1];  [2];  [3]
  1. Univ. of Bonn (Germany)
  2. RhoMed Inc., Albuquerque, NM (United States)
  3. Oak Ridge National Lab., TN (United States)

Conjugate labeling by active ester chemistry is a well-established method for labeling peptides and proteins with technetium and rhenium. The easy preparation and high conjugations yields presented in this paper show that both {sup 188}Re and {sup 99m}Tc-MAG{sub 3} p-nitrophenyl esters are promising agents for labeling a wide range of biomolecules for radio therapy or diagnostic imaging.

Research Organization:
Oak Ridge National Lab., TN (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
AC05-84OR21400
OSTI ID:
10184756
Report Number(s):
CONF-9409117-1; ON: DE94019157; TRN: 94:008811
Resource Relation:
Conference: 4. international symposium on technetium in chemistry and nuclear chemistry,Bressanone (Italy),12-14 Sep 1994; Other Information: PBD: [1994]
Country of Publication:
United States
Language:
English