RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D
Abstract
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), funded by the US National Science Foundation, National Institutes of Health, and Department of Energy, has served structural biologists and Protein Data Bank (PDB) data consumers worldwide since 1999. RCSB PDB, a founding member of the Worldwide Protein Data Bank (wwPDB) partnership, is the US data center for the global PDB archive housing biomolecular structure data. RCSB PDB is also responsible for the security of PDB data, as the wwPDB‐designated Archive Keeper. Annually, RCSB PDB serves tens of thousands of three‐dimensional (3D) macromolecular structure data depositors (using macromolecular crystallography, nuclear magnetic resonance spectroscopy, electron microscopy, and micro‐electron diffraction) from all inhabited continents. RCSB PDB makes PDB data available from its research‐focused RCSB.org web portal at no charge and without usage restrictions to millions of PDB data consumers working in every nation and territory worldwide. In addition, RCSB PDB operates an outreach and education PDB101.RCSB.org web portal that was used by more than 800,000 educators, students, and members of the public during calendar year 2020. This invited Tools Issue contribution describes (i) how the archive is growing and evolving as new experimental methods generate ever larger and more complexmore »
- Authors:
-
more »
- Rutgers University, Piscataway, NJ (United States); University of California San Diego, La Jolla, CA (United States)
- Rutgers University, Piscataway, NJ (United States)
- University of California San Diego, La Jolla, CA (United States)
- University of California, San Francisco, CA (United States)
- Rutgers University, Piscataway, NJ (United States); The Scripps Research Institute, La Jolla, CA (United States)
- Publication Date:
- Research Org.:
- Rutgers Univ., Piscataway, NJ (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC); National Science Foundation (NSF); National Cancer Institute (NCI); National Institute of Allergy and Infectious Diseases (NIAID); National Institutes of Health (NIH)
- OSTI Identifier:
- 1976373
- Alternate Identifier(s):
- OSTI ID: 1829368
- Grant/Contract Number:
- SC0019749; DBI-1832184; R01GM133198; DE‐SC0019749
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Protein Science
- Additional Journal Information:
- Journal Volume: 31; Journal Issue: 1; Journal ID: ISSN 0961-8368
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; protein data bank; PDB; open access; RCSB protein data bank; worldwide protein data bank; Mol*; web-native molecular graphics; macromolecular crystallography; electron microscopy; micro-electron diffraction
Citation Formats
Burley, Stephen K., Bhikadiya, Charmi, Bi, Chunxiao, Bittrich, Sebastian, Chen, Li, Crichlow, Gregg V., Duarte, Jose M., Dutta, Shuchismita, Fayazi, Maryam, Feng, Zukang, Flatt, Justin W., Ganesan, Sai J., Goodsell, David S., Ghosh, Sutapa, Kramer Green, Rachel, Guranovic, Vladimir, Henry, Jeremy, Hudson, Brian P., Lawson, Catherine L., Liang, Yuhe, Lowe, Robert, Peisach, Ezra, Persikova, Irina, Piehl, Dennis W., Rose, Yana, Sali, Andrej, Segura, Joan, Sekharan, Monica, Shao, Chenghua, Vallat, Brinda, Voigt, Maria, Westbrook, John D., Whetstone, Shamara, Young, Jasmine Y., and Zardecki, Christine. RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D. United States: N. p., 2021.
Web. doi:10.1002/pro.4213.
Burley, Stephen K., Bhikadiya, Charmi, Bi, Chunxiao, Bittrich, Sebastian, Chen, Li, Crichlow, Gregg V., Duarte, Jose M., Dutta, Shuchismita, Fayazi, Maryam, Feng, Zukang, Flatt, Justin W., Ganesan, Sai J., Goodsell, David S., Ghosh, Sutapa, Kramer Green, Rachel, Guranovic, Vladimir, Henry, Jeremy, Hudson, Brian P., Lawson, Catherine L., Liang, Yuhe, Lowe, Robert, Peisach, Ezra, Persikova, Irina, Piehl, Dennis W., Rose, Yana, Sali, Andrej, Segura, Joan, Sekharan, Monica, Shao, Chenghua, Vallat, Brinda, Voigt, Maria, Westbrook, John D., Whetstone, Shamara, Young, Jasmine Y., & Zardecki, Christine. RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D. United States. https://doi.org/10.1002/pro.4213
Burley, Stephen K., Bhikadiya, Charmi, Bi, Chunxiao, Bittrich, Sebastian, Chen, Li, Crichlow, Gregg V., Duarte, Jose M., Dutta, Shuchismita, Fayazi, Maryam, Feng, Zukang, Flatt, Justin W., Ganesan, Sai J., Goodsell, David S., Ghosh, Sutapa, Kramer Green, Rachel, Guranovic, Vladimir, Henry, Jeremy, Hudson, Brian P., Lawson, Catherine L., Liang, Yuhe, Lowe, Robert, Peisach, Ezra, Persikova, Irina, Piehl, Dennis W., Rose, Yana, Sali, Andrej, Segura, Joan, Sekharan, Monica, Shao, Chenghua, Vallat, Brinda, Voigt, Maria, Westbrook, John D., Whetstone, Shamara, Young, Jasmine Y., and Zardecki, Christine. Fri .
"RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D". United States. https://doi.org/10.1002/pro.4213. https://www.osti.gov/servlets/purl/1976373.
@article{osti_1976373,
title = {RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D},
author = {Burley, Stephen K. and Bhikadiya, Charmi and Bi, Chunxiao and Bittrich, Sebastian and Chen, Li and Crichlow, Gregg V. and Duarte, Jose M. and Dutta, Shuchismita and Fayazi, Maryam and Feng, Zukang and Flatt, Justin W. and Ganesan, Sai J. and Goodsell, David S. and Ghosh, Sutapa and Kramer Green, Rachel and Guranovic, Vladimir and Henry, Jeremy and Hudson, Brian P. and Lawson, Catherine L. and Liang, Yuhe and Lowe, Robert and Peisach, Ezra and Persikova, Irina and Piehl, Dennis W. and Rose, Yana and Sali, Andrej and Segura, Joan and Sekharan, Monica and Shao, Chenghua and Vallat, Brinda and Voigt, Maria and Westbrook, John D. and Whetstone, Shamara and Young, Jasmine Y. and Zardecki, Christine},
abstractNote = {Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), funded by the US National Science Foundation, National Institutes of Health, and Department of Energy, has served structural biologists and Protein Data Bank (PDB) data consumers worldwide since 1999. RCSB PDB, a founding member of the Worldwide Protein Data Bank (wwPDB) partnership, is the US data center for the global PDB archive housing biomolecular structure data. RCSB PDB is also responsible for the security of PDB data, as the wwPDB‐designated Archive Keeper. Annually, RCSB PDB serves tens of thousands of three‐dimensional (3D) macromolecular structure data depositors (using macromolecular crystallography, nuclear magnetic resonance spectroscopy, electron microscopy, and micro‐electron diffraction) from all inhabited continents. RCSB PDB makes PDB data available from its research‐focused RCSB.org web portal at no charge and without usage restrictions to millions of PDB data consumers working in every nation and territory worldwide. In addition, RCSB PDB operates an outreach and education PDB101.RCSB.org web portal that was used by more than 800,000 educators, students, and members of the public during calendar year 2020. This invited Tools Issue contribution describes (i) how the archive is growing and evolving as new experimental methods generate ever larger and more complex biomolecular structures; (ii) the importance of data standards and data remediation in effective management of the archive and facile integration with more than 50 external data resources; and (iii) new tools and features for 3D structure analysis and visualization made available during the past year via the RCSB.org web portal.},
doi = {10.1002/pro.4213},
journal = {Protein Science},
number = 1,
volume = 31,
place = {United States},
year = {Fri Oct 22 00:00:00 EDT 2021},
month = {Fri Oct 22 00:00:00 EDT 2021}
}
Works referenced in this record:
The Protein Data Bank and structural genomics
journal, January 2003
- Westbrook, J.
- Nucleic Acids Research, Vol. 31, Issue 1
Multivariate Analyses of Quality Metrics for Crystal Structures in the PDB Archive
journal, March 2017
- Shao, Chenghua; Yang, Huanwang; Westbrook, John D.
- Structure, Vol. 25, Issue 3
Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures
journal, May 2021
- Sehnal, David; Bittrich, Sebastian; Deshpande, Mandar
- Nucleic Acids Research, Vol. 49, Issue W1
Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum
journal, August 2021
- Liu, Chang; Ginn, Helen M.; Dejnirattisai, Wanwisa
- Cell, Vol. 184, Issue 16
TM-align: a protein structure alignment algorithm based on the TM-score
journal, April 2005
- Zhang, Y.
- Nucleic Acids Research, Vol. 33, Issue 7
The PDB data uniformity project
journal, January 2001
- Bhat, T. N.
- Nucleic Acids Research, Vol. 29, Issue 1
Impact of the Protein Data Bank Across Scientific Disciplines
journal, January 2020
- Feng, Zukang; Verdiguel, Natalie; Di Costanzo, Luigi
- Data Science Journal, Vol. 19, Issue 1
GlyTouCan: an accessible glycan structure repository
journal, August 2017
- Tiemeyer, Michael; Aoki, Kazuhiro; Paulson, James
- Glycobiology, Vol. 27, Issue 10
The Cambridge Structural Database
journal, April 2016
- Groom, Colin R.; Bruno, Ian J.; Lightfoot, Matthew P.
- Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, Vol. 72, Issue 2, p. 171-179
FATCAT: a web server for flexible structure comparison and structure similarity searching
journal, July 2004
- Ye, Y.; Godzik, A.
- Nucleic Acids Research, Vol. 32, Issue Web Server
Announcing the worldwide Protein Data Bank
journal, December 2003
- Berman, Helen; Henrick, Kim; Nakamura, Haruki
- Nature Structural & Molecular Biology, Vol. 10, Issue 12
Identification of common molecular subsequences
journal, March 1981
- Smith, T. F.; Waterman, M. S.
- Journal of Molecular Biology, Vol. 147, Issue 1, p. 195-197
The RCSB Protein Data Bank: redesigned web site and web services
journal, October 2010
- Rose, P. W.; Beran, B.; Bi, C.
- Nucleic Acids Research, Vol. 39, Issue Database
Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors
journal, February 2021
- Osipiuk, Jerzy; Azizi, Saara-Anne; Dvorkin, Steve
- Nature Communications, Vol. 12, Issue 1
The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
journal, November 2019
- Andreeva, Antonina; Kulesha, Eugene; Gough, Julian
- Nucleic Acids Research, Vol. 48, Issue D1
RCSB Protein Data Bank: Enabling biomedical research and drug discovery
journal, November 2019
- Goodsell, David S.; Zardecki, Christine; Di Costanzo, Luigi
- Protein Science, Vol. 29, Issue 1
The international glycan repository GlyTouCan version 3.0
journal, October 2020
- Fujita, Akihiro; Aoki, Nobuyuki P.; Shinmachi, Daisuke
- Nucleic Acids Research, Vol. 49, Issue D1
Manual classification strategies in the ECOD database: ECOD Manual Classification Strategies
journal, May 2015
- Cheng, Hua; Liao, Yuxing; Schaeffer, R. Dustin
- Proteins: Structure, Function, and Bioinformatics, Vol. 83, Issue 7
The GlyCosmos Portal: a unified and comprehensive web resource for the glycosciences
journal, June 2020
- Yamada, Issaku; Shiota, Masaaki; Shinmachi, Daisuke
- Nature Methods, Vol. 17, Issue 7
Open-access data: A cornerstone for artificial intelligence approaches to protein structure prediction
journal, June 2021
- Burley, Stephen K.; Berman, Helen M.
- Structure, Vol. 29, Issue 6
PubChem in 2021: new data content and improved web interfaces
journal, November 2020
- Kim, Sunghwan; Chen, Jie; Cheng, Tiejun
- Nucleic Acids Research, Vol. 49, Issue D1
Remediation of the protein data bank archive
journal, December 2007
- Henrick, K.; Feng, Z.; Bluhm, W. F.
- Nucleic Acids Research, Vol. 36, Issue Database
OneDep: Unified wwPDB System for Deposition, Biocuration, and Validation of Macromolecular Structures in the PDB Archive
journal, March 2017
- Young, Jasmine Y.; Westbrook, John D.; Feng, Zukang
- Structure, Vol. 25, Issue 3
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
journal, February 2020
- Wrapp, Daniel; Wang, Nianshuang; Corbett, Kizzmekia S.
- Science, Vol. 367, Issue 6483
Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography
journal, March 2021
- Kneller, Daniel W.; Phillips, Gwyndalyn; Weiss, Kevin L.
- Journal of Medicinal Chemistry, Vol. 64, Issue 8
Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
journal, April 2017
- Yuan, Yuan; Cao, Duanfang; Zhang, Yanfang
- Nature Communications, Vol. 8, Issue 1
Retrieval of Crystallographically-Derived Molecular Geometry Information
journal, November 2004
- Bruno, Ian J.; Cole, Jason C.; Kessler, Magnus
- Journal of Chemical Information and Computer Sciences, Vol. 44, Issue 6
Outlier analyses of the Protein Data Bank archive using a probability-density-ranking approach
journal, December 2018
- Shao, Chenghua; Liu, Zonghong; Yang, Huanwang
- Scientific Data, Vol. 5, Issue 1
Improved methods for building protein models in electron density maps and the location of errors in these models
journal, March 1991
- Jones, T. A.; Zou, J. Y.; Cowan, S. W.
- Acta Crystallographica Section A Foundations of Crystallography, Vol. 47, Issue 2, p. 110-119
RCSB Protein Data Bank: Architectural Advances Towards Integrated Searching and Efficient Access to Macromolecular Structure Data from the PDB Archive
journal, November 2020
- Rose, Yana; Duarte, Jose M.; Lowe, Robert
- Journal of Molecular Biology
Real-time structural motif searching in proteins using an inverted index strategy
journal, December 2020
- Bittrich, Sebastian; Burley, Stephen K.; Rose, Alexander S.
- PLOS Computational Biology, Vol. 16, Issue 12
The chemical component dictionary: complete descriptions of constituent molecules in experimentally determined 3D macromolecules in the Protein Data Bank
journal, December 2014
- Westbrook, John D.; Shao, Chenghua; Feng, Zukang
- Bioinformatics, Vol. 31, Issue 8
Modernized uniform representation of carbohydrate molecules in the Protein Data Bank
journal, May 2021
- Shao, Chenghua; Feng, Zukang; Westbrook, John D.
- Glycobiology, Vol. 31, Issue 9
Crystallography Open Database (COD): an open-access collection of crystal structures and platform for world-wide collaboration
journal, November 2011
- Gražulis, Saulius; Daškevič, Adriana; Merkys, Andrius
- Nucleic Acids Research, Vol. 40, Issue D1
The Protein Data Bank: unifying the archive
journal, January 2002
- Westbrook, J.
- Nucleic Acids Research, Vol. 30, Issue 1
From integrative structural biology to cell biology
journal, January 2021
- Sali, Andrej
- Journal of Biological Chemistry, Vol. 296
RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences
journal, November 2020
- Burley, Stephen K.; Bhikadiya, Charmi; Bi, Chunxiao
- Nucleic Acids Research, Vol. 49, Issue D1
Detection of circular permutations within protein structures using CE-CP
journal, December 2014
- Bliven, S. E.; Bourne, P. E.; Prli , A.
- Bioinformatics, Vol. 31, Issue 8
Real time structural search of the Protein Data Bank
journal, July 2020
- Guzenko, Dmytro; Burley, Stephen K.; Duarte, Jose M.
- PLOS Computational Biology, Vol. 16, Issue 7
Analysis of impact metrics for the Protein Data Bank
journal, October 2018
- Markosian, Christopher; Di Costanzo, Luigi; Sekharan, Monica
- Scientific Data, Vol. 5, Issue 1
Crystallographic structure of an intact IgG1 monoclonal antibody 1 1Edited by I. A. Wilson
journal, February 1998
- Harris, Lisa J.; Skaletsky, Eileen; McPherson, Alexander
- Journal of Molecular Biology, Vol. 275, Issue 5
ChEBI in 2016: Improved services and an expanding collection of metabolites
journal, October 2015
- Hastings, Janna; Owen, Gareth; Dekker, Adriano
- Nucleic Acids Research, Vol. 44, Issue D1
How Structural Biologists and the Protein Data Bank Contributed to Recent FDA New Drug Approvals
journal, February 2019
- Westbrook, John D.; Burley, Stephen K.
- Structure, Vol. 27, Issue 2
SAbDab: the structural antibody database
journal, November 2013
- Dunbar, James; Krawczyk, Konrad; Leem, Jinwoo
- Nucleic Acids Research, Vol. 42, Issue D1
Membrane positioning for high- and low-resolution protein structures through a binary classification approach
journal, December 2015
- Postic, Guillaume; Ghouzam, Yassine; Guiraud, Vincent
- Protein Engineering Design and Selection, Vol. 29, Issue 3
Serine Protease Mechanism and Specificity
journal, December 2002
- Hedstrom, Lizbeth
- Chemical Reviews, Vol. 102, Issue 12
RCSB Protein Data Bank: A Resource for Chemical, Biochemical, and Structural Explorations of Large and Small Biomolecules
journal, December 2015
- Zardecki, Christine; Dutta, Shuchismita; Goodsell, David S.
- Journal of Chemical Education, Vol. 93, Issue 3
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
journal, April 2020
- Jin, Zhenming; Du, Xiaoyu; Xu, Yechun
- Nature, Vol. 582, Issue 7811
PDBTM: Protein Data Bank of transmembrane proteins after 8 years
journal, November 2012
- Kozma, Dániel; Simon, István; Tusnády, Gábor E.
- Nucleic Acids Research, Vol. 41, Issue D1
STAR/mmCIF: An ontology for macromolecular structure
journal, February 2000
- Westbrook, J. D.; Bourne, P. E.
- Bioinformatics, Vol. 16, Issue 2
The ChEMBL database in 2017
journal, November 2016
- Gaulton, Anna; Hersey, Anne; Nowotka, Michał
- Nucleic Acids Research, Vol. 45, Issue D1
Protein structure alignment by incremental combinatorial extension (CE) of the optimal path
journal, September 1998
- Shindyalov, I. N.; Bourne, P. E.
- Protein Engineering Design and Selection, Vol. 11, Issue 9
DrugBank 5.0: a major update to the DrugBank database for 2018
journal, November 2017
- Wishart, David S.; Feunang, Yannick D.; Guo, An C.
- Nucleic Acids Research, Vol. 46, Issue D1
Impact of structural biologists and the Protein Data Bank on small-molecule drug discovery and development
journal, January 2021
- Burley, Stephen K.
- Journal of Biological Chemistry, Vol. 296
A global coalition to sustain core data
journal, March 2017
- Anderson, Warwick P.
- Nature, Vol. 543, Issue 7644
Improving the representation of peptide-like inhibitor and antibiotic molecules in the Protein Data Bank: Representation of Peptide-Like Inhibitor and Antibiotic Molecules
journal, March 2014
- Dutta, Shuchismita; Dimitropoulos, Dimitris; Feng, Zukang
- Biopolymers, Vol. 101, Issue 6
Fast determination of the optimal rotational matrix for macromolecular superpositions
journal, January 2009
- Liu, Pu; Agrafiotis, Dimitris K.; Theobald, Douglas L.
- Journal of Computational Chemistry
The distribution and query systems of the RCSB Protein Data Bank
journal, January 2004
- Bourne, P. E.
- Nucleic Acids Research, Vol. 32, Issue 90001
BioJava 5: A community driven open-source bioinformatics library
journal, February 2019
- Lafita, Aleix; Bliven, Spencer; Prlić, Andreas
- PLOS Computational Biology, Vol. 15, Issue 2
MolProbity : all-atom structure validation for macromolecular crystallography
journal, December 2009
- Chen, Vincent B.; Arendall, W. Bryan; Headd, Jeffrey J.
- Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 1
RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy
journal, October 2018
- Burley, Stephen K.; Berman, Helen M.; Bhikadiya, Charmi
- Nucleic Acids Research, Vol. 47, Issue D1
Transmembrane proteins in the Protein Data Bank: identification and classification
journal, June 2004
- Tusnady, G. E.; Dosztanyi, Z.; Simon, I.
- Bioinformatics, Vol. 20, Issue 17
Highly accurate protein structure prediction for the human proteome
journal, July 2021
- Tunyasuvunakool, Kathryn; Adler, Jonas; Wu, Zachary
- Nature, Vol. 596, Issue 7873
The MemProtMD database: a resource for membrane-embedded protein structures and their lipid interactions
journal, November 2018
- Newport, Thomas D.; Sansom, Mark S. P.; Stansfeld, Phillip J.
- Nucleic Acids Research, Vol. 47, Issue D1
Crystallography: Protein Data Bank
journal, October 1971
- Skipper, Magdalena
- Nature New Biology, Vol. 233, Issue 42, p. 223-223
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
journal, April 2020
- Walls, Alexandra C.; Park, Young-Jun; Tortorici, M. Alejandra
- Cell, Vol. 181, Issue 2
Validation of Structures in the Protein Data Bank
journal, December 2017
- Gore, Swanand; Sanz García, Eduardo; Hendrickx, Pieter M. S.
- Structure, Vol. 25, Issue 12
Structural impact on SARS-CoV-2 spike protein by D614G substitution
journal, April 2021
- Zhang, Jun; Cai, Yongfei; Xiao, Tianshu
- Science, Vol. 372, Issue 6541
Structural model of the SARS coronavirus E channel in LMPG micelles
journal, June 2018
- Surya, Wahyu; Li, Yan; Torres, Jaume
- Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1860, Issue 6
Protein Data Bank: the single global archive for 3D macromolecular structure data
journal, October 2018
- Burley, Stephen K.; Berman, Helen M.; Bhikadiya, Charmi
- Nucleic Acids Research, Vol. 47, Issue D1
GlyGen: Computational and Informatics Resources for Glycoscience
journal, October 2019
- York, William S.; Mazumder, Raja; Ranzinger, Rene
- Glycobiology, Vol. 30, Issue 2
Impact of the Protein Data Bank on antineoplastic approvals
journal, May 2020
- Westbrook, John D.; Soskind, Rose; Hudson, Brian P.
- Drug Discovery Today, Vol. 25, Issue 5
OPM: Orientations of Proteins in Membranes database
journal, January 2006
- Lomize, M. A.; Lomize, A. L.; Pogozheva, I. D.
- Bioinformatics, Vol. 22, Issue 5
How to help the free market fight coronavirus
journal, March 2020
- Burley, Stephen K.
- Nature, Vol. 580, Issue 7802
Between objectivity and subjectivity
journal, February 1990
- Bränd´en, Carl-Ivar; Alwyn Jones, T.
- Nature, Vol. 343, Issue 6260
Landscape of Innovation for Cardiovascular Pharmaceuticals: From Basic Science to New Molecular Entities
journal, July 2017
- Beierlein, Jennifer M.; McNamee, Laura M.; Walsh, Michael J.
- Clinical Therapeutics, Vol. 39, Issue 7
Investigation of protein quaternary structure via stoichiometry and symmetry ınformation
journal, June 2018
- Korkmaz, Selcuk; Duarte, Jose M.; Prlić, Andreas
- PLOS ONE, Vol. 13, Issue 6
RCSB Protein Data Bank 1D tools and services
journal, December 2020
- Segura, Joan; Rose, Yana; Westbrook, John
- Bioinformatics, Vol. 36, Issue 22-23
Worldwide Protein Data Bank biocuration supporting open access to high-quality 3D structural biology data
journal, January 2018
- Young, Jasmine Y.; Westbrook, John D.; Feng, Zukang
- Database, Vol. 2018
Responsible Data Science
journal, June 2017
- van der Aalst, Wil M. P.; Bichler, Martin; Heinzl, Armin
- Business & Information Systems Engineering, Vol. 59, Issue 5
Enhanced validation of small-molecule ligands and carbohydrates in the Protein Data Bank
journal, April 2021
- Feng, Zukang; Westbrook, John D.; Sala, Raul
- Structure, Vol. 29, Issue 4
PDB ‐101: Educational resources supporting molecular explorations through biology and medicine
journal, October 2021
- Zardecki, Christine; Dutta, Shuchismita; Goodsell, David S.
- Protein Science, Vol. 31, Issue 1
Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing
journal, December 2019
- Liu, Bin; Chen, Siwei; Rose, Anouk La
- Nucleic Acids Research, Vol. 48, Issue 2
Simplified quality assessment for small-molecule ligands in the Protein Data Bank
journal, February 2022
- Shao, Chenghua; Westbrook, John D.; Lu, Changpeng
- Structure, Vol. 30, Issue 2