Harvesting 62Zn from an aqueous cocktail at the NSCL
Abstract
“Isotope harvesting” is a technique that offers access to exotic radionuclides created as by-products during nuclear science research. Ongoing exploratory work at the National Superconducting Cyclotron Laboratory (NSCL) is directed towards the production and extraction of rare radionuclides from a flowing-water target and intends to pave the way for future harvesting efforts at the upcoming Facility for Rare Isotope Beams (FRIB). Here in this paper, we present the collection of 62Zn from an aqueous matrix irradiated with a 150 MeV/nucleon 78Kr beam, while synergistically capturing other gaseous reaction products. In addition to the production rate for 62Zn (9.08(30)E-5 62Zn per incoming 78Kr), the rates of formation for several other radionuclides were determined as well. The purification of 62Zn from a large number of co-produced radionuclides was performed by anion exchange chromatography, allowing the isolation of 80.5(5.2) % of the generated 62Zn. With the decay of 62Zn the radioactive daughter 62Cu is generated, and with the isolation of pure 62Cu eluate, the principle of a medical radionuclide generator could be demonstrated. To illustrate the applicability of the obtained 62Zn, the isolated product was used in free and DTPA-labelled form in a proof of principle plant uptake study with garden cress employingmore »
- Authors:
-
[1]
- Michigan State Univ., East Lansing, MI (United States). National Superconducting Cyclotron Lab.
- Publication Date:
- Research Org.:
- Michigan State Univ., East Lansing, MI (United States)
- Sponsoring Org.:
- USDOE National Nuclear Security Administration (NNSA); USDOE Office of Science (SC), Engineering & Technology. Office of Isotope R&D and Production
- OSTI Identifier:
- 1713180
- Alternate Identifier(s):
- OSTI ID: 1724231
- Grant/Contract Number:
- SC0018637; NA0003864
- Resource Type:
- Accepted Manuscript
- Journal Name:
- New Journal of Chemistry
- Additional Journal Information:
- Journal Volume: 44; Journal Issue: 47; Journal ID: ISSN 1144-0546
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 07 ISOTOPE AND RADIATION SOURCES
Citation Formats
Domnanich, Katharina, Vyas, Chirag K., Abel, E. Paige, Kalman, Colton, Walker, Wesley, and Severin, Gregory W. Harvesting 62Zn from an aqueous cocktail at the NSCL. United States: N. p., 2020.
Web. doi:10.1039/d0nj04411c.
Domnanich, Katharina, Vyas, Chirag K., Abel, E. Paige, Kalman, Colton, Walker, Wesley, & Severin, Gregory W. Harvesting 62Zn from an aqueous cocktail at the NSCL. United States. https://doi.org/10.1039/d0nj04411c
Domnanich, Katharina, Vyas, Chirag K., Abel, E. Paige, Kalman, Colton, Walker, Wesley, and Severin, Gregory W. Mon .
"Harvesting 62Zn from an aqueous cocktail at the NSCL". United States. https://doi.org/10.1039/d0nj04411c. https://www.osti.gov/servlets/purl/1713180.
@article{osti_1713180,
title = {Harvesting 62Zn from an aqueous cocktail at the NSCL},
author = {Domnanich, Katharina and Vyas, Chirag K. and Abel, E. Paige and Kalman, Colton and Walker, Wesley and Severin, Gregory W.},
abstractNote = {“Isotope harvesting” is a technique that offers access to exotic radionuclides created as by-products during nuclear science research. Ongoing exploratory work at the National Superconducting Cyclotron Laboratory (NSCL) is directed towards the production and extraction of rare radionuclides from a flowing-water target and intends to pave the way for future harvesting efforts at the upcoming Facility for Rare Isotope Beams (FRIB). Here in this paper, we present the collection of 62Zn from an aqueous matrix irradiated with a 150 MeV/nucleon 78Kr beam, while synergistically capturing other gaseous reaction products. In addition to the production rate for 62Zn (9.08(30)E-5 62Zn per incoming 78Kr), the rates of formation for several other radionuclides were determined as well. The purification of 62Zn from a large number of co-produced radionuclides was performed by anion exchange chromatography, allowing the isolation of 80.5(5.2) % of the generated 62Zn. With the decay of 62Zn the radioactive daughter 62Cu is generated, and with the isolation of pure 62Cu eluate, the principle of a medical radionuclide generator could be demonstrated. To illustrate the applicability of the obtained 62Zn, the isolated product was used in free and DTPA-labelled form in a proof of principle plant uptake study with garden cress employing phosphor imaging for visualization.},
doi = {10.1039/d0nj04411c},
journal = {New Journal of Chemistry},
number = 47,
volume = 44,
place = {United States},
year = {Mon Nov 16 00:00:00 EST 2020},
month = {Mon Nov 16 00:00:00 EST 2020}
}
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