Target highlights from the first post-PSI CASP experiment (CASP12, May–August 2016)
Abstract
In this paper, the functional and biological significance of the selected CASP12 targets are described by the authors of the structures. Finally, the crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.
- Authors:
-
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- Univ. of California, Davis, CA (United States). Genome Center
- Max Planck Inst. for Developmental Biology, Tübingen (Germany). Dept. of Protein Evolution
- Newcastle Univ., Newcastle upon Tyne (United Kingdom). Inst. for Cell and Molecular Biosciences
- Univ. of Lisbon (Portugal). Faculty of Veterinary Medicine. Centre for Interdisciplinary Research in Animal Health (CIISA)
- Univ. of Oxford (United Kingdom). Oxford Glycobiology Inst. Dept. of Biochemistry
- New Univ. of Lisbon (Portugal). Chemistry Dept. UCIBIO. Chemistry and Technology Network (REQUIMTE)
- Univ. of Maryland, Rockville, MD (United States). Inst. for Bioscience and Biotechnology Research
- Weizmann Inst. of Science, Rehovot (Israel). Dept. of Structural Biology
- Univ. of Copenhagen (Denmark). Dept. of Chemistry
- Univ. of California, Irvine, CA (United States). Dept. of Molecular Biology and Biochemistry/Pharmaceutical Sciences
- Univ. of California, Santa Barbara, CA (United States). Dept. of Molecular, Cellular and Developmental Biology. Biomolecular Science and Engineering Program
- Univ. of Maryland, Rockville, MD (United States). Inst. for Bioscience and Biotechnology Research; Univ. of Maryland, College Park, MD (United States). Dept. of Chemistry and Biochemistry
- Argonne National Lab. (ANL), Argonne, IL (United States). Midwest Center for Structural Genomics. Structural Biology Center. Biosciences Division; Univ. of Chicago, IL (United States). Dept. of Biochemistry and Molecular Biology
- Saarland Univ., Saarbrücken (Germany). Microbiology
- Leiden Univ. (Netherlands). Netherlands Centre for Electron Nanoscopy. Inst. of Biology Leiden; Leiden Univ. Medical Center (Netherlands). Dept. of Molecular Cell Biology
- Univ. of Milano-Bicocca, Milan (Italy). Dept. of Biotechnology and Biosciences
- Argonne National Lab. (ANL), Argonne, IL (United States). Midwest Center for Structural Genomics. Structural Biology Center. Biosciences Division
- Univ. of Maryland, Rockville, MD (United States). Dept. of Cell Biology and Molecular Genetics. Inst. for Bioscience and Biotechnology Research
- Univ. of Milan (Italy). Dept. of Biosciences
- CSIC National Center for Biotechnology (CNB), Madrid (Spain). Dept. of Macromolecular Structures
- Univ. of Lyon (France). Center for High Field NMR (CRMN). Inst. of Analytical Sciences
- Univ. of Maryland School of Medicine, Baltimore, MD (United States). Inst. of Human Virology
- Univ. of Oxford (United Kingdom). Oxford Glycobiology Inst. Dept. of Biochemistry; Univ. of Leicester (United Kingdom). Leicester Inst. of Structural and Chemical Biology. Dept. of Molecular and Cell Biology
- Univ. of Kent, Canterbury (United Kingdom). School of Biosciences
- Univ. of Maryland School of Medicine, Baltimore, MD (United States). Dept. of Medicine. Dept. of Microbiology and Immunology. Inst. of Human Virology
- Latvian Biomedical Research and Study Center, Riga (Latvia); Univ. of Latvia, Riga (Latvia). Faculty of Biology. Dept. of Molecular Biology
- SIB Swiss Inst. of Bioinformatics, Basel (Switzerland)
- Publication Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States); Univ. of California, Davis, CA (United States); Univ. of Maryland, Rockville, MD (United States); Univ. of Latvia, Riga (Latvia); Max Planck Inst. for Developmental Biology, Tübingen (Germany); Weizmann Institute of Science, Rehovot (Israel); Newcastle University, Newcastle upon Tyne (United Kingdom); Univ. of Oxford (United Kingdom); CSIC National Center for Biotechnology (CNB), Madrid (Spain); Univ. of Lisbon (Portugal)
- Sponsoring Org.:
- USDOE Office of Science (SC), Biological and Environmental Research (BER); National Inst. of Health (NIH) (United States); Latvian Council of Sciences; European Regional Development Fund (ERDF); European Union (EU); Israel Science Foundation (ISF); Wellcome Trust (United Kingdom); Ministry of Economy and Competitiveness (MINECO) (Spain); Foundation for Science and Technology (FCT) (Portugal)
- OSTI Identifier:
- 1461425
- Alternate Identifier(s):
- OSTI ID: 1399794
- Grant/Contract Number:
- AC02-06CH11357; GM100482; GM102318; GM094585; GM115586; R01GM102810; 12.094; 2010/0314/2DP/2.1.1.1.0/10/APIA/VIAA/052; NMP3-SL-2008-213487; 682/16; 097300/Z/11/Z; 106272/Z/14/Z; BFU2014-53425-P; PTDC/BIA-MIC/5947/2014; RECI/BBB-BEP/0124/2012; SFRH/BD/86821/2012
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Proteins
- Additional Journal Information:
- Journal Volume: 86; Journal Issue: S1; Journal ID: ISSN 0887-3585
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; CASP; NMR; protein structure prediction; X-ray crystallography
Citation Formats
Kryshtafovych, Andriy, Albrecht, Reinhard, Basle, Arnaud, Bule, Pedro, Caputo, Alessandro T., Carvalho, Ana Luisa, Chao, Kinlin L., Diskin, Ron, Fidelis, Krzysztof, Fontes, Carlos M. G. A., Fredslund, Folmer, Gilbert, Harry J., Goulding, Celia W., Hartmann, Marcus D., Hayes, Christopher S., Herzberg, Osnat, Hill, Johan C., Joachimiak, Andrzej, Kohring, Gert-Wieland, Koning, Roman I., Lo Leggio, Leila, Mangiagalli, Marco, Michalska, Karolina, Moult, John, Najmudin, Shabir, Nardini, Marco, Nardone, Valentina, Ndeh, Didier, Nguyen, Thanh-Hong, Pintacuda, Guido, Postel, Sandra, van Raaij, Mark J., Roversi, Pietro, Shimon, Amir, Singh, Abhimanyu K., Sundberg, Eric J., Tars, Kaspars, Zitzmann, Nicole, and Schwede, Torsten. Target highlights from the first post-PSI CASP experiment (CASP12, May–August 2016). United States: N. p., 2017.
Web. doi:10.1002/prot.25392.
Kryshtafovych, Andriy, Albrecht, Reinhard, Basle, Arnaud, Bule, Pedro, Caputo, Alessandro T., Carvalho, Ana Luisa, Chao, Kinlin L., Diskin, Ron, Fidelis, Krzysztof, Fontes, Carlos M. G. A., Fredslund, Folmer, Gilbert, Harry J., Goulding, Celia W., Hartmann, Marcus D., Hayes, Christopher S., Herzberg, Osnat, Hill, Johan C., Joachimiak, Andrzej, Kohring, Gert-Wieland, Koning, Roman I., Lo Leggio, Leila, Mangiagalli, Marco, Michalska, Karolina, Moult, John, Najmudin, Shabir, Nardini, Marco, Nardone, Valentina, Ndeh, Didier, Nguyen, Thanh-Hong, Pintacuda, Guido, Postel, Sandra, van Raaij, Mark J., Roversi, Pietro, Shimon, Amir, Singh, Abhimanyu K., Sundberg, Eric J., Tars, Kaspars, Zitzmann, Nicole, & Schwede, Torsten. Target highlights from the first post-PSI CASP experiment (CASP12, May–August 2016). United States. https://doi.org/10.1002/prot.25392
Kryshtafovych, Andriy, Albrecht, Reinhard, Basle, Arnaud, Bule, Pedro, Caputo, Alessandro T., Carvalho, Ana Luisa, Chao, Kinlin L., Diskin, Ron, Fidelis, Krzysztof, Fontes, Carlos M. G. A., Fredslund, Folmer, Gilbert, Harry J., Goulding, Celia W., Hartmann, Marcus D., Hayes, Christopher S., Herzberg, Osnat, Hill, Johan C., Joachimiak, Andrzej, Kohring, Gert-Wieland, Koning, Roman I., Lo Leggio, Leila, Mangiagalli, Marco, Michalska, Karolina, Moult, John, Najmudin, Shabir, Nardini, Marco, Nardone, Valentina, Ndeh, Didier, Nguyen, Thanh-Hong, Pintacuda, Guido, Postel, Sandra, van Raaij, Mark J., Roversi, Pietro, Shimon, Amir, Singh, Abhimanyu K., Sundberg, Eric J., Tars, Kaspars, Zitzmann, Nicole, and Schwede, Torsten. Thu .
"Target highlights from the first post-PSI CASP experiment (CASP12, May–August 2016)". United States. https://doi.org/10.1002/prot.25392. https://www.osti.gov/servlets/purl/1461425.
@article{osti_1461425,
title = {Target highlights from the first post-PSI CASP experiment (CASP12, May–August 2016)},
author = {Kryshtafovych, Andriy and Albrecht, Reinhard and Basle, Arnaud and Bule, Pedro and Caputo, Alessandro T. and Carvalho, Ana Luisa and Chao, Kinlin L. and Diskin, Ron and Fidelis, Krzysztof and Fontes, Carlos M. G. A. and Fredslund, Folmer and Gilbert, Harry J. and Goulding, Celia W. and Hartmann, Marcus D. and Hayes, Christopher S. and Herzberg, Osnat and Hill, Johan C. and Joachimiak, Andrzej and Kohring, Gert-Wieland and Koning, Roman I. and Lo Leggio, Leila and Mangiagalli, Marco and Michalska, Karolina and Moult, John and Najmudin, Shabir and Nardini, Marco and Nardone, Valentina and Ndeh, Didier and Nguyen, Thanh-Hong and Pintacuda, Guido and Postel, Sandra and van Raaij, Mark J. and Roversi, Pietro and Shimon, Amir and Singh, Abhimanyu K. and Sundberg, Eric J. and Tars, Kaspars and Zitzmann, Nicole and Schwede, Torsten},
abstractNote = {In this paper, the functional and biological significance of the selected CASP12 targets are described by the authors of the structures. Finally, the crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.},
doi = {10.1002/prot.25392},
journal = {Proteins},
number = S1,
volume = 86,
place = {United States},
year = {Thu Sep 28 00:00:00 EDT 2017},
month = {Thu Sep 28 00:00:00 EDT 2017}
}
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