Recent Advances in Nanomaterials for Gene Delivery—A Review
Abstract
With the rapid development of nanotechnology in the recent decade, novel DNA and RNA delivery systems for gene therapy have become available that can be used instead of viral vectors. These non-viral vectors can be made of a variety of materials, including inorganic nanoparticles, carbon nanotubes, liposomes, protein and peptide-based nanoparticles, as well as nanoscale polymeric materials. They have as advantages over viral vectors a decreased immune response, and additionally offer flexibility in design, allowing them to be functionalized and targeted to specific sites in a biological system with low cytotoxicity. The focus of this review is to provide an overview of novel nanotechnology-based methods to deliver DNA and small interfering RNAs into biological systems.
- Authors:
-
- Univ. of Florida, Gainesville, FL (United States)
- Publication Date:
- Research Org.:
- Univ. of Florida, Gainesville, FL (United States)
- Sponsoring Org.:
- USDOE Office of Energy Efficiency and Renewable Energy (EERE), Transportation Office. Bioenergy Technologies Office; USDOE Office of International Affairs (IA)
- OSTI Identifier:
- 1426434
- Alternate Identifier(s):
- OSTI ID: 1767999
- Grant/Contract Number:
- PI0000031
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Nanomaterials
- Additional Journal Information:
- Journal Volume: 7; Journal Issue: 12; Journal ID: ISSN 2079-4991
- Publisher:
- MDPI
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; gene delivery; nanomaterials; non-viral vectors; siRNA
Citation Formats
Riley, II, Michael K., and Vermerris, Wilfred. Recent Advances in Nanomaterials for Gene Delivery—A Review. United States: N. p., 2017.
Web. doi:10.3390/nano7050094.
Riley, II, Michael K., & Vermerris, Wilfred. Recent Advances in Nanomaterials for Gene Delivery—A Review. United States. https://doi.org/10.3390/nano7050094
Riley, II, Michael K., and Vermerris, Wilfred. Fri .
"Recent Advances in Nanomaterials for Gene Delivery—A Review". United States. https://doi.org/10.3390/nano7050094. https://www.osti.gov/servlets/purl/1426434.
@article{osti_1426434,
title = {Recent Advances in Nanomaterials for Gene Delivery—A Review},
author = {Riley, II, Michael K. and Vermerris, Wilfred},
abstractNote = {With the rapid development of nanotechnology in the recent decade, novel DNA and RNA delivery systems for gene therapy have become available that can be used instead of viral vectors. These non-viral vectors can be made of a variety of materials, including inorganic nanoparticles, carbon nanotubes, liposomes, protein and peptide-based nanoparticles, as well as nanoscale polymeric materials. They have as advantages over viral vectors a decreased immune response, and additionally offer flexibility in design, allowing them to be functionalized and targeted to specific sites in a biological system with low cytotoxicity. The focus of this review is to provide an overview of novel nanotechnology-based methods to deliver DNA and small interfering RNAs into biological systems.},
doi = {10.3390/nano7050094},
journal = {Nanomaterials},
number = 12,
volume = 7,
place = {United States},
year = {Fri Apr 28 00:00:00 EDT 2017},
month = {Fri Apr 28 00:00:00 EDT 2017}
}
Web of Science
Works referenced in this record:
Gene therapy clinical trials worldwide to 2012 - an update: Gene therapy clinical trials worldwide to 2012 - an update
journal, February 2013
- Ginn, Samantha L.; Alexander, Ian E.; Edelstein, Michael L.
- The Journal of Gene Medicine, Vol. 15, Issue 2
Helical microtubules of graphitic carbon
journal, November 1991
- Iijima, Sumio
- Nature, Vol. 354, Issue 6348
Physiochemical Properties of Low and High Molecular Weight Poly(ethylene glycol)-Grafted Poly(ethylene imine) Copolymers and Their Complexes with Oligonucleotides
journal, January 2006
- Glodde, Martin; Sirsi, Shashank R.; Lutz, Gordon J.
- Biomacromolecules, Vol. 7, Issue 1
cRGD grafted liposomes containing inorganic nano-precipitate complexed siRNA for intracellular delivery in cancer cells
journal, May 2014
- Khatri, Nirav; Baradia, Dipesh; Vhora, Imran
- Journal of Controlled Release, Vol. 182
Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery
journal, April 1999
- Dash, P. R.; Read, M. L.; Barrett, L. B.
- Gene Therapy, Vol. 6, Issue 4
Estradiol functionalized multi-walled carbon nanotubes as renovated strategy for efficient gene delivery
journal, January 2016
- Jain, Sanyog; Thanki, Kaushik; Pandi, Nagesh Kumar
- RSC Advances, Vol. 6, Issue 13
Noncovalent Engineering of Carbon Nanotube Surfaces by Rigid, Functional Conjugated Polymers
journal, August 2002
- Chen, Jian; Liu, Haiying; Weimer, Wayne A.
- Journal of the American Chemical Society, Vol. 124, Issue 31
Protein Nanoparticles as Drug Delivery Carriers for Cancer Therapy
journal, January 2014
- Lohcharoenkal, Warangkana; Wang, Liying; Chen, Yi Charlie
- BioMed Research International, Vol. 2014
Stimuli-triggered structural engineering of synthetic and biological polymeric assemblies
journal, August 2012
- Zhang, Jianxiang; Li, Xiaodong; Li, Xiaohui
- Progress in Polymer Science, Vol. 37, Issue 8
Polymer vectors via controlled/living radical polymerization for gene delivery
journal, September 2011
- Xu, F. J.; Yang, W. T.
- Progress in Polymer Science, Vol. 36, Issue 9
Nonthermal plasma synthesis of semiconductor nanocrystals
journal, May 2009
- Kortshagen, Uwe
- Journal of Physics D: Applied Physics, Vol. 42, Issue 11
Efficient Transfection of Embryonic and Adult Stem Cells
journal, July 2004
- Lakshmipathy, U.
- Stem Cells, Vol. 22, Issue 4
The Cationic Cell-Penetrating Peptide CPP TAT Derived from the HIV-1 Protein TAT Is Rapidly Transported into Living Fibroblasts: Optical, Biophysical, and Metabolic Evidence †
journal, January 2005
- Ziegler, André; Nervi, Pierluigi; Dürrenberger, Markus
- Biochemistry, Vol. 44, Issue 1
Noncovalent functionalization of carbon nanotubes by aromatic organic molecules
journal, May 2003
- Zhao, Jijun; Lu, Jian Ping; Han, Jie
- Applied Physics Letters, Vol. 82, Issue 21
Pleiotropic functions of magnetic nanoparticles for ex vivo gene transfer
journal, August 2014
- Kami, Daisuke; Kitani, Tomoya; Kishida, Tsunao
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 6
Antitumor immunologically modified carbon nanotubes for photothermal therapy
journal, April 2012
- Zhou, Feifan; Wu, Shengnan; Song, Sheng
- Biomaterials, Vol. 33, Issue 11
A pH-responsive cyclodextrin-based hybrid nanosystem as a nonviral vector for gene delivery
journal, May 2013
- Chen, Huaping; Liu, Xueping; Dou, Yin
- Biomaterials, Vol. 34, Issue 16
Integration of antimicrobial peptides with gold nanoparticles as unique non-viral vectors for gene delivery to mesenchymal stem cells with antibacterial activity
journal, October 2016
- Peng, Li-Hua; Huang, Yan-Fen; Zhang, Chen-Zhen
- Biomaterials, Vol. 103
Gelatin-based nanoparticles as DNA delivery systems: Synthesis, physicochemical and biocompatible characterization
journal, October 2015
- Morán, M. C.; Rosell, N.; Ruano, G.
- Colloids and Surfaces B: Biointerfaces, Vol. 134
TAT conjugated cationic noble metal nanoparticles for gene delivery to epidermal stem cells
journal, July 2014
- Peng, Li-Hua; Niu, Jie; Zhang, Chen-Zhen
- Biomaterials, Vol. 35, Issue 21
Poly(ethylene glycol)-block-cationic polylactide nanocomplexes of differing charge density for gene delivery
journal, December 2013
- Chen, Chih-Kuang; Jones, Charles H.; Mistriotis, Panagiotis
- Biomaterials, Vol. 34, Issue 37
Band Gap Fluorescence from Individual Single-Walled Carbon Nanotubes
journal, July 2002
- O'Connell, Michael J.; Bachilo, Sergei M.; Huffman, Chad B.
- Science, Vol. 297, Issue 5581, p. 593-596
Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu
journal, June 1992
- Benz, Christopher C.; Scott, Gary K.; Sarup, Jay C.
- Breast Cancer Research and Treatment, Vol. 24, Issue 2
Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: Towards non-invasive glaucoma gene therapy
journal, November 2014
- Alqawlaq, Samih; Sivak, Jeremy M.; Huzil, J. Torin
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 8
Synthesis and Characterization of Monodisperse Nanocrystals and Close-Packed Nanocrystal Assemblies
journal, August 2000
- Murray, C. B.; Kagan, C. R.; Bawendi, M. G.
- Annual Review of Materials Science, Vol. 30, Issue 1, p. 545-610
Maintaining the silence: reflections on long-term RNAi
journal, November 2008
- Raemdonck, Koen; Vandenbroucke, Roosmarijn E.; Demeester, Joseph
- Drug Discovery Today, Vol. 13, Issue 21-22
Cationic Bovine Serum Albumin Based Self-Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer
journal, September 2013
- Han, Jianfeng; Wang, Qin; Zhang, Zhirong
- Small, Vol. 10, Issue 3
Cross-Linked Nanoassemblies from Poly(ethylene glycol)-poly(aspartate) Block Copolymers as Stable Supramolecular Templates for Particulate Drug Delivery
journal, July 2011
- Lee, Hyun Jin; Bae, Younsoo
- Biomacromolecules, Vol. 12, Issue 7
Silk-based biomaterials
journal, February 2003
- Altman, Gregory H.; Diaz, Frank; Jakuba, Caroline
- Biomaterials, Vol. 24, Issue 3, p. 401-416
Tunable elastin-like polypeptide hollow sphere as a high payload and controlled delivery gene depot
journal, June 2011
- Dash, Biraja C.; Mahor, Sunil; Carroll, Oliver
- Journal of Controlled Release, Vol. 152, Issue 3
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
journal, May 2001
- Elbashir, Sayda M.; Harborth, Jens; Lendeckel, Winfried
- Nature, Vol. 411, Issue 6836, p. 494-498
Active targeting schemes for nanoparticle systems in cancer therapeutics
journal, December 2008
- Byrne, James D.; Betancourt, Tania; Brannon-Peppas, Lisa
- Advanced Drug Delivery Reviews, Vol. 60, Issue 15
Endgame: Glybera Finally Recommended for Approval as the First Gene Therapy Drug in the European Union
journal, October 2012
- Ylä-Herttuala, Seppo
- Molecular Therapy, Vol. 20, Issue 10
Single-shell carbon nanotubes of 1-nm diameter
journal, June 1993
- Iijima, Sumio; Ichihashi, Toshinari
- Nature, Vol. 363, Issue 6430
Gene therapy and DNA delivery systems
journal, January 2014
- Ibraheem, D.; Elaissari, A.; Fessi, H.
- International Journal of Pharmaceutics, Vol. 459, Issue 1-2
Different types of degradable vectors from low-molecular-weight polycation-functionalized poly(aspartic acid) for efficient gene delivery
journal, March 2014
- Dou, X. B.; Hu, Y.; Zhao, N. N.
- Biomaterials, Vol. 35, Issue 9
Lignins: Natural polymers from oxidative coupling of 4-hydroxyphenyl- propanoids
journal, January 2004
- Ralph, John; Lundquist, Knut; Brunow, Gösta
- Phytochemistry Reviews, Vol. 3, Issue 1-2, p. 29-60
The effect of quantum dot size and poly(ethylenimine) coating on the efficiency of gene delivery into human mesenchymal stem cells
journal, September 2014
- Yang, Han Na; Park, Ji Sun; Jeon, Su Yeon
- Biomaterials, Vol. 35, Issue 29
Organic Functionalization of Carbon Nanotubes
journal, February 2002
- Georgakilas, Vasilios; Kordatos, Konstantinos; Prato, Maurizio
- Journal of the American Chemical Society, Vol. 124, Issue 5
Functionalized Graphene Oxide Mediated Adriamycin Delivery and miR-21 Gene Silencing to Overcome Tumor Multidrug Resistance In Vitro
journal, March 2013
- Zhi, Feng; Dong, Haifeng; Jia, Xuefeng
- PLoS ONE, Vol. 8, Issue 3
The covalent bioconjugate of multiwalled carbon nanotube and amino-modified linearized plasmid DNA for gene delivery
journal, November 2013
- Geyik, Caner; Evran, Serap; Timur, Suna
- Biotechnology Progress, Vol. 30, Issue 1
Silk fibroin layer-by-layer microcapsules for localized gene delivery
journal, September 2014
- Li, Linhao; Puhl, Sebastian; Meinel, Lorenz
- Biomaterials, Vol. 35, Issue 27
A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants
journal, October 1999
- Hamilton, A. J.
- Science, Vol. 286, Issue 5441
Evaluation of Magnetic and Thermal Properties of Ferrite Nanoparticles for Biomedical Applications
journal, June 2011
- Tomitaka, Asahi; Jeun, Min-Hong; Bae, Seong-Tae
- Journal of Magnetics, Vol. 16, Issue 2
A Graphene Platform for Sensing Biomolecules
journal, June 2009
- Lu, Chun‐Hua; Yang, Huang‐Hao; Zhu, Chun‐Ling
- Angewandte Chemie, Vol. 121, Issue 26
Noncovalent Sidewall Functionalization of Single-Walled Carbon Nanotubes for Protein Immobilization
journal, April 2001
- Chen, Robert J.; Zhang, Yuegang; Wang, Dunwei
- Journal of the American Chemical Society, Vol. 123, Issue 16
Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing Regimes
journal, February 1997
- Radler, J. O.
- Science, Vol. 275, Issue 5301
The novel albumin–chitosan core–shell nanoparticles for gene delivery: preparation, optimization and cell uptake investigation
journal, April 2013
- Karimi, Mahdi; Avci, Pinar; Mobasseri, Rezvan
- Journal of Nanoparticle Research, Vol. 15, Issue 5
Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery
journal, February 2009
- Liu, Zhuang; Tabakman, Scott; Welsher, Kevin
- Nano Research, Vol. 2, Issue 2
Lysosomes: fusion and function
journal, August 2007
- Luzio, J. Paul; Pryor, Paul R.; Bright, Nicholas A.
- Nature Reviews Molecular Cell Biology, Vol. 8, Issue 8
Biocompatible multi-walled carbon nanotube-chitosan–folic acid nanoparticle hybrids as GFP gene delivery materials
journal, November 2013
- Liu, Xiahui; Zhang, Yingying; Ma, Dongmei
- Colloids and Surfaces B: Biointerfaces, Vol. 111
Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers
journal, January 2014
- Jin, Lian; Zeng, Xin; Liu, Ming
- Theranostics, Vol. 4, Issue 3
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
journal, June 2014
- Whitehead, Kathryn A.; Dorkin, J. Robert; Vegas, Arturo J.
- Nature Communications, Vol. 5, Issue 1
PEGylated cyclodextrins as novel siRNA nanosystems: Correlations between polyethylene glycol length and nanoparticle stability
journal, October 2014
- Godinho, Bruno M. D. C.; Ogier, Julien R.; Quinlan, Aoife
- International Journal of Pharmaceutics, Vol. 473, Issue 1-2
Smart Carbon Nanotubes with Laser-Controlled Behavior in Gene Delivery and Therapy through a Non-Digestive Trafficking Pathway
journal, September 2016
- Kong, Fenfen; Liu, Fei; Li, Wei
- Small, Vol. 12, Issue 48
An injectable elastin-based gene delivery platform for dose-dependent modulation of angiogenesis and inflammation for critical limb ischemia
journal, October 2015
- Dash, Biraja C.; Thomas, Dilip; Monaghan, Michael
- Biomaterials, Vol. 65
Noncovalent Functionalization of Carbon Nanotubes by Fluorescein−Polyethylene Glycol: Supramolecular Conjugates with pH-Dependent Absorbance and Fluorescence
journal, March 2007
- Nakayama-Ratchford, Nozomi; Bangsaruntip, Sarunya; Sun, Xiaoming
- Journal of the American Chemical Society, Vol. 129, Issue 9
Sheltering DNA in self-organizing, protein-only nano-shells as artificial viruses for gene delivery
journal, April 2014
- Unzueta, Ugutz; Saccardo, Paolo; Domingo-Espín, Joan
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 3
Gene delivery to Her-2+ breast cancer cells using a two-component delivery system to achieve specificity
journal, August 2014
- Kullberg, Max; McCarthy, Ryan; Anchordoquy, Thomas J.
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 6
Gemini Surfactants: A New Family of Building Blocks for Non-Viral Gene Delivery Systems
journal, February 2008
- Wettig, Shawn; Verrall, Ronald; Foldvari, Marianna
- Current Gene Therapy, Vol. 8, Issue 1
Lignin Nanotubes As Vehicles for Gene Delivery into Human Cells
journal, December 2013
- Ten, Elena; Ling, Chen; Wang, Yuan
- Biomacromolecules, Vol. 15, Issue 1
Virus-mediated gene delivery for human gene therapy
journal, July 2012
- Giacca, Mauro; Zacchigna, Serena
- Journal of Controlled Release, Vol. 161, Issue 2
Non-covalently functionalized single-walled carbon nanotube for topical siRNA delivery into melanoma
journal, March 2014
- Siu, King Sun; Chen, Di; Zheng, Xiufen
- Biomaterials, Vol. 35, Issue 10
Chemistry of Single-Walled Carbon Nanotubes
journal, December 2002
- Niyogi, S.; Hamon, M. A.; Hu, H.
- Accounts of Chemical Research, Vol. 35, Issue 12
Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures
journal, September 2002
- Florea, Bogdan I.; Meaney, Clare; Junginger, Hans E.
- AAPS PharmSci, Vol. 4, Issue 3
In Vivo Safety Evaluation of Polyarginine Coated Magnetic Nanovectors
journal, October 2013
- Veiseh, Omid; Kievit, Forrest M.; Liu, Vicki
- Molecular Pharmaceutics, Vol. 10, Issue 11
High-Efficiency Loading and Controlled Release of Doxorubicin Hydrochloride on Graphene Oxide
journal, October 2008
- Yang, Xiaoying; Zhang, Xiaoyan; Liu, Zunfeng
- The Journal of Physical Chemistry C, Vol. 112, Issue 45
Branched Polyethylenimine Derivatives with Reductively Cleavable Periphery for Safe and Efficient In Vitro Gene Transfer
journal, April 2011
- Wang, Yuhe; Zheng, Meng; Meng, Fenghua
- Biomacromolecules, Vol. 12, Issue 4
Progress and prospects: immune responses to viral vectors
journal, November 2009
- Nayak, S.; Herzog, R. W.
- Gene Therapy, Vol. 17, Issue 3
Cell transfection with polycationic cyclodextrin vectors
journal, April 2004
- Cryan, Sally-Ann; Holohan, Ann; Donohue, Ruth
- European Journal of Pharmaceutical Sciences, Vol. 21, Issue 5
Cyclodextrins as Building Blocks for Supramolecular Structures and Functional Units
journal, May 1994
- Wenz, Gerhard
- Angewandte Chemie International Edition in English, Vol. 33, Issue 8
Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy
journal, January 2011
- Mahmoudi, Morteza; Sant, Shilpa; Wang, Ben
- Advanced Drug Delivery Reviews, Vol. 63, Issue 1-2, p. 24-46
Protein Transduction: Cell Penetrating Peptides and Their Therapeutic Applications
journal, May 2006
- Wagstaff, Kylie; Jans, David
- Current Medicinal Chemistry, Vol. 13, Issue 12
Physical Non-Viral Gene Delivery Methods for Tissue Engineering
journal, October 2012
- Mellott, Adam J.; Forrest, M. Laird; Detamore, Michael S.
- Annals of Biomedical Engineering, Vol. 41, Issue 3
Non-viral magnetic engineering of endothelial cells with microRNA and plasmid-DNA—An optimized targeting approach
journal, November 2016
- Voronina, Natalia; Lemcke, Heiko; Wiekhorst, Frank
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 12, Issue 8
Photothermally Controlled Gene Delivery by Reduced Graphene Oxide-Polyethylenimine Nanocomposite
journal, May 2013
- Kim, Hyunwoo; Kim, Won Jong
- Small, Vol. 10, Issue 1
Template-mediated synthesis and bio-functionalization of flexible lignin-based nanotubes and nanowires
journal, February 2012
- Caicedo, Hector M.; Dempere, Luisa A.; Vermerris, Wilfred
- Nanotechnology, Vol. 23, Issue 10
Gene delivery by lipoplexes and polyplexes
journal, June 2010
- Tros de Ilarduya, Conchita; Sun, Yan; Düzgüneş, Nejat
- European Journal of Pharmaceutical Sciences, Vol. 40, Issue 3
Fabrication of electrospun zein nanofibers for the sustained delivery of siRNA
journal, February 2015
- Karthikeyan, K.; Krishnaswamy, Venkat Raghavan; Lakra, Rachita
- Journal of Materials Science: Materials in Medicine, Vol. 26, Issue 2
Gelatin Behaviour in Dilute Aqueous Solution: Designing a Nanoparticulate Formulation
journal, June 1999
- Farrugia, Claude A.; Groves, Michael J.
- Journal of Pharmacy and Pharmacology, Vol. 51, Issue 6
Targeted integration of adeno-associated virus (AAV) into human chromosome 19.
journal, December 1991
- Samulski, R. J.; Zhu, X.; Xiao, X.
- The EMBO Journal, Vol. 10, Issue 12
Some Properties of Sodium Dodecyl Sulfate Functionalized Multiwalled Carbon Nanotubes Electrode and Its Application on Detection of Dopamine in the Presence of Ascorbic Acid
journal, August 2008
- Zheng, Dan; Ye, Jianshan; Zhang, Weide
- Electroanalysis, Vol. 20, Issue 16
Endocytic recycling
journal, February 2004
- Maxfield, Frederick R.; McGraw, Timothy E.
- Nature Reviews Molecular Cell Biology, Vol. 5, Issue 2
Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo
journal, November 2016
- Evans, James C.; Malhotra, Meenakshi; Guo, Jianfeng
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 12, Issue 8
Using graphene to protect DNA from cleavage during cellular delivery
journal, January 2010
- Lu, Chun-Hua; Zhu, Chun-Ling; Li, Juan
- Chemical Communications, Vol. 46, Issue 18
Lipidoid nanoparticle mediated silencing of Mcl-1 induces apoptosis in mantle cell lymphoma
journal, March 2016
- Knapp, Christopher M.; He, Jia; Lister, John
- Experimental Biology and Medicine, Vol. 241, Issue 9
Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.
journal, November 1987
- Felgner, P. L.; Gadek, T. R.; Holm, M.
- Proceedings of the National Academy of Sciences, Vol. 84, Issue 21
Well-Defined Degradable Cationic Polylactide as Nanocarrier for the Delivery of siRNA to Silence Angiogenesis in Prostate Cancer
journal, July 2012
- Chen, Chih-Kuang; Law, Wing-Cheung; Aalinkeel, Ravikumar
- Advanced Healthcare Materials, Vol. 1, Issue 6
Biocompatible gelatin nanoparticles for tumor-targeted delivery of polymerized siRNA in tumor-bearing mice
journal, November 2013
- Lee, So Jin; Yhee, Ji Young; Kim, Sun Hwa
- Journal of Controlled Release, Vol. 172, Issue 1
Carbon nanotubes: past, present, and future
journal, October 2002
- Iijima, Sumio
- Physica B: Condensed Matter, Vol. 323, Issue 1-4
Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination.
journal, December 1992
- Kotin, R. M.; Linden, R. M.; Berns, K. I.
- The EMBO Journal, Vol. 11, Issue 13
Functionalization of Inorganic Nanoparticles for Bioimaging Applications
journal, October 2011
- Erathodiyil, Nandanan; Ying, Jackie Y.
- Accounts of Chemical Research, Vol. 44, Issue 10
Doped quantum dots for chemo/biosensing and bioimaging
journal, January 2013
- Wu, Peng; Yan, Xiu-Ping
- Chemical Society Reviews, Vol. 42, Issue 12
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
journal, January 2005
- Akinc, Akin; Thomas, Mini; Klibanov, Alexander M.
- The Journal of Gene Medicine, Vol. 7, Issue 5
Physical Chemistry of Biological Free Energy Transduction As Demonstrated by Elastic Protein-Based Polymers †
journal, December 1997
- Urry, Dan W.
- The Journal of Physical Chemistry B, Vol. 101, Issue 51
From rationally designed polymeric and peptidic systems to sophisticated gene delivery nano-vectors
journal, November 2013
- Parhiz, Hamideh; Shier, Wayne Thomas; Ramezani, Mohammad
- International Journal of Pharmaceutics, Vol. 457, Issue 1
Synergistic anticancer effect of RNAi and photothermal therapy mediated by functionalized single-walled carbon nanotubes
journal, January 2013
- Wang, Lei; Shi, Jinjin; Zhang, Hongling
- Biomaterials, Vol. 34, Issue 1
Enhanced in vitro DNA transfection efficiency by novel folate-linked nanoparticles in human prostate cancer and oral cancer
journal, May 2004
- Hattori, Yoshiyuki; Maitani, Yoshie
- Journal of Controlled Release, Vol. 97, Issue 1
Fabrication and characterization of DNA-loaded zein nanospheres
journal, January 2012
- Regier, Mary C.; Taylor, Jessica D.; Borcyk, Tyler
- Journal of Nanobiotechnology, Vol. 10, Issue 1
Non-covalent functionalization of single-walled carbon nanotubes with modified polyethyleneimines for efficient gene delivery
journal, September 2013
- Behnam, Behzad; Shier, Wayne T.; Nia, Azadeh Hashem
- International Journal of Pharmaceutics, Vol. 454, Issue 1
Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery
journal, January 2013
- He, Yiyan; Cheng, Gang; Xie, Li
- Biomaterials, Vol. 34, Issue 4
Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy
journal, January 2014
- Biju, Vasudevanpillai
- Chem. Soc. Rev., Vol. 43, Issue 3
Target Specific Intracellular Delivery of siRNA/PEI−HA Complex by Receptor Mediated Endocytosis
journal, January 2009
- Jiang, Ge; Park, Kitae; Kim, Jiseok
- Molecular Pharmaceutics, Vol. 6, Issue 3
Silk-on-Silk Layer-by-Layer Microcapsules
journal, September 2011
- Shchepelina, Olga; Drachuk, Irina; Gupta, Maneesh K.
- Advanced Materials, Vol. 23, Issue 40
Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex
journal, April 2000
- Domashenko, Alevtina; Gupta, Sonya; Cotsarelis, George
- Nature Biotechnology, Vol. 18, Issue 4
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
journal, April 2008
- Akinc, Akin; Zumbuehl, Andreas; Goldberg, Michael
- Nature Biotechnology, Vol. 26, Issue 5
Zein: the industrial protein from corn
journal, May 2001
- Shukla, Rishi; Cheryan, Munir
- Industrial Crops and Products, Vol. 13, Issue 3, p. 171-192
Inhibition of hepatitis C virus in mouse models by lipidoid nanoparticle-mediated systemic delivery of siRNA against PRK2
journal, August 2016
- Moon, Jae-Su; Lee, Seung-Hoon; Han, Song-Hee
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 12, Issue 6
Combination of siRNA-directed Kras oncogene silencing and arsenic-induced apoptosis using a nanomedicine strategy for the effective treatment of pancreatic cancer
journal, February 2014
- Zeng, Linjuan; Li, Jingguo; Wang, Yong
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 2
i-Motif-Driven Au Nanomachines in Programmed siRNA Delivery for Gene-Silencing and Photothermal Ablation
journal, May 2014
- Son, Sejin; Nam, Jutaek; Kim, Jinhwan
- ACS Nano, Vol. 8, Issue 6
Nanoparticle-based theranostic agents
journal, August 2010
- Xie, Jin; Lee, Seulki; Chen, Xiaoyuan
- Advanced Drug Delivery Reviews, Vol. 62, Issue 11
A Graphene Platform for Sensing Biomolecules
journal, June 2009
- Lu, Chun-Hua; Yang, Huang-Hao; Zhu, Chun-Ling
- Angewandte Chemie International Edition, Vol. 48, Issue 26
Protein Transduction: Cell Penetrating Peptides and Their Therapeutic Applications
book, March 2012
- Wagstaff, Kylie M.; Jans, David A.
- Frontiers in Medicinal Chemistry (Volume 5)
Well-Defined Degradable Cationic Polylactide as Nanocarrier for the Delivery of siRNA to Silence Angiogenesis in Prostate Cancer
journal, July 2012
- Chen, Chih-Kuang; Law, Wing-Cheung; Aalinkeel, Ravikumar
- Advanced Healthcare Materials, Vol. 1, Issue 6
Silk-on-Silk Layer-by-Layer Microcapsules
journal, September 2011
- Shchepelina, Olga; Drachuk, Irina; Gupta, Maneesh K.
- Advanced Materials, Vol. 23, Issue 40
A Graphene Platform for Sensing Biomolecules
journal, June 2009
- Lu, Chun‐Hua; Yang, Huang‐Hao; Zhu, Chun‐Ling
- Angewandte Chemie, Vol. 121, Issue 26
Cyclodextrins as Building Blocks for Supramolecular Structures and Functional Units
journal, May 1994
- Wenz, Gerhard
- Angewandte Chemie International Edition in English, Vol. 33, Issue 8
The covalent bioconjugate of multiwalled carbon nanotube and amino-modified linearized plasmid DNA for gene delivery
journal, November 2013
- Geyik, Caner; Evran, Serap; Timur, Suna
- Biotechnology Progress, Vol. 30, Issue 1
Some Properties of Sodium Dodecyl Sulfate Functionalized Multiwalled Carbon Nanotubes Electrode and Its Application on Detection of Dopamine in the Presence of Ascorbic Acid
journal, August 2008
- Zheng, Dan; Ye, Jianshan; Zhang, Weide
- Electroanalysis, Vol. 20, Issue 16
Targeted integration of adeno-associated virus (AAV) into human chromosome 19.
journal, December 1991
- Samulski, R. J.; Zhu, X.; Xiao, X.
- The EMBO Journal, Vol. 10, Issue 12
Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination.
journal, December 1992
- Kotin, R. M.; Linden, R. M.; Berns, K. I.
- The EMBO Journal, Vol. 11, Issue 13
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
journal, January 2005
- Akinc, Akin; Thomas, Mini; Klibanov, Alexander M.
- The Journal of Gene Medicine, Vol. 7, Issue 5
Photothermally Controlled Gene Delivery by Reduced Graphene Oxide-Polyethylenimine Nanocomposite
journal, May 2013
- Kim, Hyunwoo; Kim, Won Jong
- Small, Vol. 10, Issue 1
Cationic Bovine Serum Albumin Based Self-Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer
journal, September 2013
- Han, Jianfeng; Wang, Qin; Zhang, Zhirong
- Small, Vol. 10, Issue 3
Smart Carbon Nanotubes with Laser-Controlled Behavior in Gene Delivery and Therapy through a Non-Digestive Trafficking Pathway
journal, September 2016
- Kong, Fenfen; Liu, Fei; Li, Wei
- Small, Vol. 12, Issue 48
Trans-Golgi network sorting
journal, July 2001
- Gu, F.; Crump, C. M.; Thomas, G.
- Cellular and Molecular Life Sciences, Vol. 58, Issue 8
Simulation and computational study of graphene oxide nano-carriers, absorption, and release of the anticancer drug of camptothecin
journal, August 2021
- Moradi, Omid; Mahdavian, Leila
- Journal of Molecular Modeling, Vol. 27, Issue 9
Physical Non-Viral Gene Delivery Methods for Tissue Engineering
journal, October 2012
- Mellott, Adam J.; Forrest, M. Laird; Detamore, Michael S.
- Annals of Biomedical Engineering, Vol. 41, Issue 3
Fabrication of electrospun zein nanofibers for the sustained delivery of siRNA
journal, February 2015
- Karthikeyan, K.; Krishnaswamy, Venkat Raghavan; Lakra, Rachita
- Journal of Materials Science: Materials in Medicine, Vol. 26, Issue 2
The novel albumin–chitosan core–shell nanoparticles for gene delivery: preparation, optimization and cell uptake investigation
journal, April 2013
- Karimi, Mahdi; Avci, Pinar; Mobasseri, Rezvan
- Journal of Nanoparticle Research, Vol. 15, Issue 5
Identification of tissue sites for increased albumin degradation in sarcoma-bearing mice
journal, February 1991
- Andersson, Christer; Iresjö, Britt-Marie; Lundholm, Kent
- Journal of Surgical Research, Vol. 50, Issue 2
Active targeting schemes for nanoparticle systems in cancer therapeutics
journal, December 2008
- Byrne, James D.; Betancourt, Tania; Brannon-Peppas, Lisa
- Advanced Drug Delivery Reviews, Vol. 60, Issue 15
Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy
journal, January 2011
- Mahmoudi, Morteza; Sant, Shilpa; Wang, Ben
- Advanced Drug Delivery Reviews, Vol. 63, Issue 1-2, p. 24-46
Nanoparticle-based theranostic agents
journal, August 2010
- Xie, Jin; Lee, Seulki; Chen, Xiaoyuan
- Advanced Drug Delivery Reviews, Vol. 62, Issue 11
Synergistic anticancer effect of RNAi and photothermal therapy mediated by functionalized single-walled carbon nanotubes
journal, January 2013
- Wang, Lei; Shi, Jinjin; Zhang, Hongling
- Biomaterials, Vol. 34, Issue 1
Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery
journal, January 2013
- He, Yiyan; Cheng, Gang; Xie, Li
- Biomaterials, Vol. 34, Issue 4
Poly(ethylene glycol)-block-cationic polylactide nanocomplexes of differing charge density for gene delivery
journal, December 2013
- Chen, Chih-Kuang; Jones, Charles H.; Mistriotis, Panagiotis
- Biomaterials, Vol. 34, Issue 37
Different types of degradable vectors from low-molecular-weight polycation-functionalized poly(aspartic acid) for efficient gene delivery
journal, March 2014
- Dou, X. B.; Hu, Y.; Zhao, N. N.
- Biomaterials, Vol. 35, Issue 9
Non-covalently functionalized single-walled carbon nanotube for topical siRNA delivery into melanoma
journal, March 2014
- Siu, King Sun; Chen, Di; Zheng, Xiufen
- Biomaterials, Vol. 35, Issue 10
TAT conjugated cationic noble metal nanoparticles for gene delivery to epidermal stem cells
journal, July 2014
- Peng, Li-Hua; Niu, Jie; Zhang, Chen-Zhen
- Biomaterials, Vol. 35, Issue 21
The effect of quantum dot size and poly(ethylenimine) coating on the efficiency of gene delivery into human mesenchymal stem cells
journal, September 2014
- Yang, Han Na; Park, Ji Sun; Jeon, Su Yeon
- Biomaterials, Vol. 35, Issue 29
An injectable elastin-based gene delivery platform for dose-dependent modulation of angiogenesis and inflammation for critical limb ischemia
journal, October 2015
- Dash, Biraja C.; Thomas, Dilip; Monaghan, Michael
- Biomaterials, Vol. 65
Integration of antimicrobial peptides with gold nanoparticles as unique non-viral vectors for gene delivery to mesenchymal stem cells with antibacterial activity
journal, October 2016
- Peng, Li-Hua; Huang, Yan-Fen; Zhang, Chen-Zhen
- Biomaterials, Vol. 103
Biocompatible multi-walled carbon nanotube-chitosan–folic acid nanoparticle hybrids as GFP gene delivery materials
journal, November 2013
- Liu, Xiahui; Zhang, Yingying; Ma, Dongmei
- Colloids and Surfaces B: Biointerfaces, Vol. 111
Maintaining the silence: reflections on long-term RNAi
journal, November 2008
- Raemdonck, Koen; Vandenbroucke, Roosmarijn E.; Demeester, Joseph
- Drug Discovery Today, Vol. 13, Issue 21-22
Non-covalent functionalization of single-walled carbon nanotubes with modified polyethyleneimines for efficient gene delivery
journal, September 2013
- Behnam, Behzad; Shier, Wayne T.; Nia, Azadeh Hashem
- International Journal of Pharmaceutics, Vol. 454, Issue 1
From rationally designed polymeric and peptidic systems to sophisticated gene delivery nano-vectors
journal, November 2013
- Parhiz, Hamideh; Shier, Wayne Thomas; Ramezani, Mohammad
- International Journal of Pharmaceutics, Vol. 457, Issue 1
Enhanced in vitro DNA transfection efficiency by novel folate-linked nanoparticles in human prostate cancer and oral cancer
journal, May 2004
- Hattori, Yoshiyuki; Maitani, Yoshie
- Journal of Controlled Release, Vol. 97, Issue 1
Virus-mediated gene delivery for human gene therapy
journal, July 2012
- Giacca, Mauro; Zacchigna, Serena
- Journal of Controlled Release, Vol. 161, Issue 2
Biocompatible gelatin nanoparticles for tumor-targeted delivery of polymerized siRNA in tumor-bearing mice
journal, November 2013
- Lee, So Jin; Yhee, Ji Young; Kim, Sun Hwa
- Journal of Controlled Release, Vol. 172, Issue 1
cRGD grafted liposomes containing inorganic nano-precipitate complexed siRNA for intracellular delivery in cancer cells
journal, May 2014
- Khatri, Nirav; Baradia, Dipesh; Vhora, Imran
- Journal of Controlled Release, Vol. 182
Combination of siRNA-directed Kras oncogene silencing and arsenic-induced apoptosis using a nanomedicine strategy for the effective treatment of pancreatic cancer
journal, February 2014
- Zeng, Linjuan; Li, Jingguo; Wang, Yong
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 2
Sheltering DNA in self-organizing, protein-only nano-shells as artificial viruses for gene delivery
journal, April 2014
- Unzueta, Ugutz; Saccardo, Paolo; Domingo-Espín, Joan
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 3
Pleiotropic functions of magnetic nanoparticles for ex vivo gene transfer
journal, August 2014
- Kami, Daisuke; Kitani, Tomoya; Kishida, Tsunao
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 6
Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: Towards non-invasive glaucoma gene therapy
journal, November 2014
- Alqawlaq, Samih; Sivak, Jeremy M.; Huzil, J. Torin
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 10, Issue 8
Inhibition of hepatitis C virus in mouse models by lipidoid nanoparticle-mediated systemic delivery of siRNA against PRK2
journal, August 2016
- Moon, Jae-Su; Lee, Seung-Hoon; Han, Song-Hee
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 12, Issue 6
Non-viral magnetic engineering of endothelial cells with microRNA and plasmid-DNA—An optimized targeting approach
journal, November 2016
- Voronina, Natalia; Lemcke, Heiko; Wiekhorst, Frank
- Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 12, Issue 8
Polymer vectors via controlled/living radical polymerization for gene delivery
journal, September 2011
- Xu, F. J.; Yang, W. T.
- Progress in Polymer Science, Vol. 36, Issue 9
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
journal, September 2002
- Merdan, Thomas; Kopec̆ek, Jindrich; Kissel, Thomas
- Advanced Drug Delivery Reviews, Vol. 54, Issue 5
Chemistry of Single-Walled Carbon Nanotubes
journal, December 2002
- Niyogi, S.; Hamon, M. A.; Hu, H.
- Accounts of Chemical Research, Vol. 35, Issue 12
Functionalization of Inorganic Nanoparticles for Bioimaging Applications
journal, October 2011
- Erathodiyil, Nandanan; Ying, Jackie Y.
- Accounts of Chemical Research, Vol. 44, Issue 10
The Cationic Cell-Penetrating Peptide CPP TAT Derived from the HIV-1 Protein TAT Is Rapidly Transported into Living Fibroblasts: Optical, Biophysical, and Metabolic Evidence †
journal, January 2005
- Ziegler, André; Nervi, Pierluigi; Dürrenberger, Markus
- Biochemistry, Vol. 44, Issue 1
Physiochemical Properties of Low and High Molecular Weight Poly(ethylene glycol)-Grafted Poly(ethylene imine) Copolymers and Their Complexes with Oligonucleotides
journal, January 2006
- Glodde, Martin; Sirsi, Shashank R.; Lutz, Gordon J.
- Biomacromolecules, Vol. 7, Issue 1
Branched Polyethylenimine Derivatives with Reductively Cleavable Periphery for Safe and Efficient In Vitro Gene Transfer
journal, April 2011
- Wang, Yuhe; Zheng, Meng; Meng, Fenghua
- Biomacromolecules, Vol. 12, Issue 4
Cross-Linked Nanoassemblies from Poly(ethylene glycol)-poly(aspartate) Block Copolymers as Stable Supramolecular Templates for Particulate Drug Delivery
journal, July 2011
- Lee, Hyun Jin; Bae, Younsoo
- Biomacromolecules, Vol. 12, Issue 7
Noncovalent Functionalization of Carbon Nanotubes by Fluorescein−Polyethylene Glycol: Supramolecular Conjugates with pH-Dependent Absorbance and Fluorescence
journal, March 2007
- Nakayama-Ratchford, Nozomi; Bangsaruntip, Sarunya; Sun, Xiaoming
- Journal of the American Chemical Society, Vol. 129, Issue 9
Physical Chemistry of Biological Free Energy Transduction As Demonstrated by Elastic Protein-Based Polymers †
journal, December 1997
- Urry, Dan W.
- The Journal of Physical Chemistry B, Vol. 101, Issue 51
In Vivo Safety Evaluation of Polyarginine Coated Magnetic Nanovectors
journal, October 2013
- Veiseh, Omid; Kievit, Forrest M.; Liu, Vicki
- Molecular Pharmaceutics, Vol. 10, Issue 11
Target Specific Intracellular Delivery of siRNA/PEI−HA Complex by Receptor Mediated Endocytosis
journal, January 2009
- Jiang, Ge; Park, Kitae; Kim, Jiseok
- Molecular Pharmaceutics, Vol. 6, Issue 3
Single-shell carbon nanotubes of 1-nm diameter
journal, June 1993
- Iijima, Sumio; Ichihashi, Toshinari
- Nature, Vol. 363, Issue 6430
Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex
journal, April 2000
- Domashenko, Alevtina; Gupta, Sonya; Cotsarelis, George
- Nature Biotechnology, Vol. 18, Issue 4
Endgame: Glybera Finally Recommended for Approval as the First Gene Therapy Drug in the European Union
journal, October 2012
- Ylä-Herttuala, Seppo
- Molecular Therapy, Vol. 20, Issue 10
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
journal, April 2008
- Akinc, Akin; Zumbuehl, Andreas; Goldberg, Michael
- Nature Biotechnology, Vol. 26, Issue 5
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
journal, June 2014
- Whitehead, Kathryn A.; Dorkin, J. Robert; Vegas, Arturo J.
- Nature Communications, Vol. 5, Issue 1
Lysosomes: fusion and function
journal, August 2007
- Luzio, J. Paul; Pryor, Paul R.; Bright, Nicholas A.
- Nature Reviews Molecular Cell Biology, Vol. 8, Issue 8
Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery
journal, April 1999
- Dash, P. R.; Read, M. L.; Barrett, L. B.
- Gene Therapy, Vol. 6, Issue 4
Using graphene to protect DNA from cleavage during cellular delivery
journal, January 2010
- Lu, Chun-Hua; Zhu, Chun-Ling; Li, Juan
- Chemical Communications, Vol. 46, Issue 18
Doped quantum dots for chemo/biosensing and bioimaging
journal, January 2013
- Wu, Peng; Yan, Xiu-Ping
- Chemical Society Reviews, Vol. 42, Issue 12
Noncovalent functionalization of carbon nanotubes by aromatic organic molecules
journal, May 2003
- Zhao, Jijun; Lu, Jian Ping; Han, Jie
- Applied Physics Letters, Vol. 82, Issue 21
Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.
journal, November 1987
- Felgner, P. L.; Gadek, T. R.; Holm, M.
- Proceedings of the National Academy of Sciences, Vol. 84, Issue 21
Template-mediated synthesis and bio-functionalization of flexible lignin-based nanotubes and nanowires
journal, February 2012
- Caicedo, Hector M.; Dempere, Luisa A.; Vermerris, Wilfred
- Nanotechnology, Vol. 23, Issue 10
Band Gap Fluorescence from Individual Single-Walled Carbon Nanotubes
journal, July 2002
- O'Connell, Michael J.; Bachilo, Sergei M.; Huffman, Chad B.
- Science, Vol. 297, Issue 5581, p. 593-596
Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing Regimes
journal, February 1997
- Radler, J. O.
- Science, Vol. 275, Issue 5301
A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants
journal, October 1999
- Hamilton, A. J.
- Science, Vol. 286, Issue 5441
Synthesis and Characterization of Monodisperse Nanocrystals and Close-Packed Nanocrystal Assemblies
journal, August 2000
- Murray, C. B.; Kagan, C. R.; Bawendi, M. G.
- Annual Review of Materials Science, Vol. 30, Issue 1, p. 545-610
Protein Nanoparticles as Drug Delivery Carriers for Cancer Therapy
journal, January 2014
- Lohcharoenkal, Warangkana; Wang, Liying; Chen, Yi Charlie
- BioMed Research International, Vol. 2014
Lipidoid nanoparticle mediated silencing of Mcl-1 induces apoptosis in mantle cell lymphoma
journal, March 2016
- Knapp, Christopher M.; He, Jia; Lister, John
- Experimental Biology and Medicine, Vol. 241, Issue 9
Fabrication and characterization of DNA-loaded zein nanospheres
journal, January 2012
- Regier, Mary C.; Taylor, Jessica D.; Borcyk, Tyler
- Journal of Nanobiotechnology, Vol. 10, Issue 1
Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures
journal, September 2002
- Florea, Bogdan I.; Meaney, Clare; Junginger, Hans E.
- AAPS PharmSci, Vol. 4, Issue 3
Gelatin Behaviour in Dilute Aqueous Solution: Designing a Nanoparticulate Formulation
journal, June 1999
- Farrugia, Claude A.; Groves, Michael J.
- Journal of Pharmacy and Pharmacology, Vol. 51, Issue 6
Functionalized Graphene Oxide Mediated Adriamycin Delivery and miR-21 Gene Silencing to Overcome Tumor Multidrug Resistance In Vitro
journal, March 2013
- Zhi, Feng; Dong, Haifeng; Jia, Xuefeng
- PLoS ONE, Vol. 8, Issue 3
Efficient Transfection of Embryonic and Adult Stem Cells
journal, July 2004
- Lakshmipathy, U.
- Stem Cells, Vol. 22, Issue 4
Theranostic nanoparticles based on bioreducible polyethylenimine-coated iron oxide for reduction-responsive gene delivery and magnetic resonance imaging
journal, July 2014
- Lv, Zhongwei; Li, Dan; Tang, Xing
- International Journal of Nanomedicine
Protein Transduction: Cell Penetrating Peptides and Their Therapeutic Applications
journal, May 2006
- Wagstaff, Kylie; Jans, David
- Current Medicinal Chemistry, Vol. 13, Issue 12
Carbon Nanotubes in Biology and Medicine: in vitro and in vivo Detection, Imaging and Drug Delivery
preprint, January 2009
- Liu, Zhuang; Tabakman, Scott; Welsher, Kevin
- arXiv
Works referencing / citing this record:
Controlled Non-Viral Gene Delivery in Cartilage and Bone Repair: Current Strategies and Future Directions
journal, August 2018
- Gonzalez-Fernandez, Tomas; Kelly, Daniel J.; O'Brien, Fergal J.
- Advanced Therapeutics, Vol. 1, Issue 7
A standard procedure for lentiviral‐mediated labeling of murine mesenchymal stromal cells in vitro
journal, August 2017
- Lupan, Ana‐Mihaela; Preda, Mihai Bogdan; Burlacu, Alexandrina
- Biotechnology and Applied Biochemistry, Vol. 66, Issue 4
Multifunctional Gene Carriers Labeled by Perylene Diimide Derivative as Fluorescent Probe for Tracking Gene Delivery
journal, April 2019
- Li, Qian; Hao, Xuefang; Guo, Jintang
- Macromolecular Rapid Communications, Vol. 40, Issue 12
Development of lipopolyplexes for gene delivery: A comparison of the effects of differing modes of targeting peptide display on the structure and transfection activities of lipopolyplexes
journal, October 2018
- Bofinger, Robin; Zaw-Thin, May; Mitchell, Nicholas J.
- Journal of Peptide Science, Vol. 24, Issue 12
Current trends in targeted therapy for drug-resistant infections
journal, August 2019
- Rahbarnia, Leila; Farajnia, Safar; Naghili, Behrooz
- Applied Microbiology and Biotechnology, Vol. 103, Issue 20
A needle-like optofluidic probe enables targeted intracellular delivery by confining light-nanoparticle interaction on single cell
journal, January 2018
- Doppenberg, Andrew; Meunier, Michel; Boutopoulos, Christos
- Nanoscale, Vol. 10, Issue 46
Decorating a single giant DNA with gold nanoparticles
journal, January 2018
- Carnerero, Jose M.; Masuoka, Shinsuke; Baba, Hikari
- RSC Advances, Vol. 8, Issue 47
Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery
journal, January 2019
- Wang, Pengchong; Yan, Yan; Sun, Ying
- Journal of Materials Chemistry B, Vol. 7, Issue 44
Using carbon nanotubes to deliver genes to hard-to-transfect mammalian primary fibroblast cells
journal, June 2017
- Munk, Michele; de Souza Salomão Zanette, Rafaella; de Almeida Camargo, Luiz Sérgio
- Biomedical Physics & Engineering Express, Vol. 3, Issue 4
Nanotechnology based approaches for detection and delivery of microRNA in healthcare and crop protection
journal, April 2018
- Chaudhary, Vrantika; Jangra, Sumit; Yadav, Neelam R.
- Journal of Nanobiotechnology, Vol. 16, Issue 1
Carbon nanotubes as molecular transporters to study a new mechanism for molecular entry into the cell nucleus using actin polymerization force
journal, August 2019
- Sadr Karimi, Shaghayegh; Pante, Nelly
- PLOS ONE, Vol. 14, Issue 8
The Potential of Nanotechnology in Medically Assisted Reproduction
journal, January 2018
- Remião, Mariana H.; Segatto, Natalia V.; Pohlmann, Adriana
- Frontiers in Pharmacology, Vol. 8
Aptamer Functionalized DNA Hydrogel for Wise-Stage Controlled Protein Release
journal, October 2018
- Liu, Chen; Han, Jialun; Pei, Yuxuan
- Applied Sciences, Vol. 8, Issue 10
Applications of Noble Metal-Based Nanoparticles in Medicine
journal, December 2018
- Klębowski, Bartosz; Depciuch, Joanna; Parlińska-Wojtan, Magdalena
- International Journal of Molecular Sciences, Vol. 19, Issue 12
Therapeutic potential of CRISPR/Cas9 gene editing in engineered T‐cell therapy
journal, June 2019
- Gao, Qianqian; Dong, Xuan; Xu, Qumiao
- Cancer Medicine, Vol. 8, Issue 9
Biomedical applications of carbon nanomaterials: Drug and gene delivery potentials
journal, August 2018
- Mohajeri, Mohammad; Behnam, Behzad; Sahebkar, Amirhossein
- Journal of Cellular Physiology, Vol. 234, Issue 1
New approaches to tumor therapy with siRNA-decorated and chitosan-modified PLGA nanoparticles
journal, September 2019
- Şenel, Behiye; Öztürk, A. Alper
- Drug Development and Industrial Pharmacy, Vol. 45, Issue 11
Biological Characteristics and Carrier Functions of Pegylated Manganese Zinc Ferrite Nanoparticles
journal, November 2019
- Guo, Ting; Dou, Fengxiao; Lin, Mei
- Journal of Nanomaterials, Vol. 2019
Non-Viral Vectors for Gene Delivery
journal, December 2018
- Bansal, Aparna
- Nanoscience &Nanotechnology-Asia, Vol. 9, Issue 1
Covalent Organic Frameworks: From Materials Design to Biomedical Application
journal, December 2017
- Zhao, Fuli; Liu, Huiming; Mathe, Salva
- Nanomaterials, Vol. 8, Issue 1
Engineered Nanodelivery Systems to Improve DNA Vaccine Technologies
journal, January 2020
- Lim, Michael; Badruddoza, Abu Zayed Md; Firdous, Jannatul
- Pharmaceutics, Vol. 12, Issue 1
Graphene oxide-based magnetic nanocomposites for the delivery of melittin to cervical cancer HeLa cells
journal, November 2019
- Qi, Jinxia; Chen, Yonghui; Xue, Tiantian
- Nanotechnology, Vol. 31, Issue 6
A switching role of hard-uptake nanoparticles in microalgae cell electroporation
journal, January 2019
- Chen, Zhenzhong; Lee, Won Gu
- The Analyst, Vol. 144, Issue 11
Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids
journal, September 2018
- Englezou, Pavlos C.; Sapet, Cedric; Démoulins, Thomas
- Molecular Therapy - Nucleic Acids, Vol. 12
A Systematic Review of miR-29 in Cancer
journal, March 2019
- Kwon, Jason J.; Factora, Tricia D.; Dey, Shatovisha
- Molecular Therapy - Oncolytics, Vol. 12
Application of some nanoparticles in the field of veterinary medicine
journal, January 2019
- Youssef, Fady Sayed; El-Banna, Hossny Awad; Elzorba, Hesham Youssef
- International Journal of Veterinary Science and Medicine, Vol. 7, Issue 1
Nanotechnology based approaches for detection and delivery of microRNA in healthcare and crop protection
journal, April 2018
- Chaudhary, Vrantika; Jangra, Sumit; Yadav, Neelam R.
- Journal of Nanobiotechnology, Vol. 16, Issue 1
Carbon nanotubes as molecular transporters to study a new mechanism for molecular entry into the cell nucleus using actin polymerization force
journal, August 2019
- Sadr Karimi, Shaghayegh; Pante, Nelly
- PLOS ONE, Vol. 14, Issue 8
The Potential of Nanotechnology in Medically Assisted Reproduction
journal, January 2018
- Remião, Mariana H.; Segatto, Natalia V.; Pohlmann, Adriana
- Frontiers in Pharmacology, Vol. 8
Applications of Noble Metal-Based Nanoparticles in Medicine
journal, December 2018
- Klębowski, Bartosz; Depciuch, Joanna; Parlińska-Wojtan, Magdalena
- International Journal of Molecular Sciences, Vol. 19, Issue 12
Comprehensive Survey on Nanobiomaterials for Bone Tissue Engineering Applications
journal, October 2020
- Kumar, Pawan; Saini, Meenu; Dehiya, Brijnandan S.
- Nanomaterials, Vol. 10, Issue 10
Magnetic Cationic Amylose Nanoparticles Used to Deliver Survivin-Small Interfering RNA for Gene Therapy of Hepatocellular Carcinoma In Vitro
journal, May 2017
- Wu, Zhuo; Xu, Xiao-Lin; Zhang, Jun-Zhao
- Nanomaterials, Vol. 7, Issue 5
Covalent Organic Frameworks: From Materials Design to Biomedical Application
journal, December 2017
- Zhao, Fuli; Liu, Huiming; Mathe, Salva
- Nanomaterials, Vol. 8, Issue 1
Silicon Nanotubes as Potential Therapeutic Platforms
journal, November 2019
- Le, Nguyen T.; Tian, Yuan; Gonzalez-Rodriguez, Roberto
- Pharmaceutics, Vol. 11, Issue 11
Engineered Nanodelivery Systems to Improve DNA Vaccine Technologies
journal, January 2020
- Lim, Michael; Badruddoza, Abu Zayed Md; Firdous, Jannatul
- Pharmaceutics, Vol. 12, Issue 1
Comparative Study of Diethylaminoethyl-Chitosan and Methylglycol-Chitosan as Potential Non-Viral Vectors for Gene Therapy
journal, April 2018
- Raik, Sergei; Andranovitš, Stanislav; Petrova, Valentina
- Polymers, Vol. 10, Issue 4
Magnetic ternary nanohybrids for nonviral gene delivery of stem cells and applications on cancer therapy
journal, January 2019
- Huang, Rih-Yang; Lin, Yee-Hsien; Lin, Ssu-Yu
- Theranostics, Vol. 9, Issue 8