Considerations for Bioassay Monitoring of Mixtures of Radionuclides

Klumpp, John; Waters, Tom; Bertelli, Luiz

doi:10.1097/HP.0000000000000707

Title: Considerations for Bioassay Monitoring of Mixtures of Radionuclides

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Abstract

Complying with regulations for bioassay monitoring of radionuclide intakes is significantly more complex for mixtures than it is for pure radionuclides. Different constituents will naturally have different dose coefficients, be detectable at significantly different levels, and may require very different amounts of effort to bioassay. The ability to use certain constituents as surrogates for others will depend on how well characterized the mixture is, as well as whether the employee is also working with other radionuclides. This is further compounded by the fact that the composition of a mixture (or even of a pure radionuclide) is likely to change over time. Internal dosimetrists must decide how best to monitor employees who work with radionuclide mixtures. In particular, they must decide which constituents should be monitored routinely, which constituents only need to be monitored in the case of an intake, and how to estimate doses based on intakes of monitored and unmonitored constituents.

Authors:

Klumpp, John ^[1]; Waters, Tom ^[1]; Bertelli, Luiz ^[1]

Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

Publication Date:: Sun Oct 01 00:00:00 EDT 2017

Research Org.:: Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1396119

Report Number(s):: LA-UR-17-20012
Journal ID: ISSN 0017-9078

Grant/Contract Number:: AC52-06NA25396

Resource Type:: Accepted Manuscript

Journal Name:: Health Physics

Additional Journal Information:: Journal Volume: 113; Journal Issue: 4; Journal ID: ISSN 0017-9078

Publisher:: Health Physics Society

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE

Citation Formats


                    Klumpp, John, Waters, Tom, and Bertelli, Luiz. Considerations for Bioassay Monitoring of Mixtures of Radionuclides.  United States: N. p., 2017. 
Web.  doi:10.1097/HP.0000000000000707.

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                    Klumpp, John, Waters, Tom, & Bertelli, Luiz. Considerations for Bioassay Monitoring of Mixtures of Radionuclides.  United States.  https://doi.org/10.1097/HP.0000000000000707

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                    Klumpp, John, Waters, Tom, and Bertelli, Luiz. Sun .  
"Considerations for Bioassay Monitoring of Mixtures of Radionuclides".  United States.  https://doi.org/10.1097/HP.0000000000000707.  https://www.osti.gov/servlets/purl/1396119.

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@article{osti_1396119,

  title        = {Considerations for Bioassay Monitoring of Mixtures of Radionuclides},

  author       = {Klumpp, John and Waters, Tom and Bertelli, Luiz},

  abstractNote = {Complying with regulations for bioassay monitoring of radionuclide intakes is significantly more complex for mixtures than it is for pure radionuclides. Different constituents will naturally have different dose coefficients, be detectable at significantly different levels, and may require very different amounts of effort to bioassay. The ability to use certain constituents as surrogates for others will depend on how well characterized the mixture is, as well as whether the employee is also working with other radionuclides. This is further compounded by the fact that the composition of a mixture (or even of a pure radionuclide) is likely to change over time. Internal dosimetrists must decide how best to monitor employees who work with radionuclide mixtures. In particular, they must decide which constituents should be monitored routinely, which constituents only need to be monitored in the case of an intake, and how to estimate doses based on intakes of monitored and unmonitored constituents.},

  doi          = {10.1097/HP.0000000000000707},

  journal      = {Health Physics},

  number       = 4,

  volume       = 113,

  place        = {United States},

  year         = {Sun Oct 01 00:00:00 EDT 2017},

  month        = {Sun Oct 01 00:00:00 EDT 2017}

}

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