Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering
Abstract
In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. Finally, these results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.
- Authors:
-
[1];
[2];
- Yale Univ., New Haven, CT (United States)
- Sandia National Lab. (SNL-CA), Livermore, CA (United States)
- Publication Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE National Nuclear Security Administration (NNSA)
- OSTI Identifier:
- 1369304
- Report Number(s):
- SAND-2017-6779J
Journal ID: ISSN 1359-7345; CHCOFS; 654840
- Grant/Contract Number:
- AC04-94AL85000
- Resource Type:
- Accepted Manuscript
- Journal Name:
- ChemComm
- Additional Journal Information:
- Journal Volume: 53; Journal Issue: 59; Journal ID: ISSN 1359-7345
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 36 MATERIALS SCIENCE
Citation Formats
Li, Jinyang, Gittleson, Forrest S., Liu, Yanhui, Liu, Jingbei, Loye, Ayomiposi M., McMillon-Brown, Lyndsey, Kyriakides, Themis R., Schroers, Jan, and Taylor, Andre D. Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering. United States: N. p., 2017.
Web. doi:10.1039/c7cc02733h.
Li, Jinyang, Gittleson, Forrest S., Liu, Yanhui, Liu, Jingbei, Loye, Ayomiposi M., McMillon-Brown, Lyndsey, Kyriakides, Themis R., Schroers, Jan, & Taylor, Andre D. Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering. United States. https://doi.org/10.1039/c7cc02733h
Li, Jinyang, Gittleson, Forrest S., Liu, Yanhui, Liu, Jingbei, Loye, Ayomiposi M., McMillon-Brown, Lyndsey, Kyriakides, Themis R., Schroers, Jan, and Taylor, Andre D. Fri .
"Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering". United States. https://doi.org/10.1039/c7cc02733h. https://www.osti.gov/servlets/purl/1369304.
@article{osti_1369304,
title = {Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering},
author = {Li, Jinyang and Gittleson, Forrest S. and Liu, Yanhui and Liu, Jingbei and Loye, Ayomiposi M. and McMillon-Brown, Lyndsey and Kyriakides, Themis R. and Schroers, Jan and Taylor, Andre D.},
abstractNote = {In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. Finally, these results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.},
doi = {10.1039/c7cc02733h},
journal = {ChemComm},
number = 59,
volume = 53,
place = {United States},
year = {Fri Jun 30 00:00:00 EDT 2017},
month = {Fri Jun 30 00:00:00 EDT 2017}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 21 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Role of partially amorphous structure and alloying elements on the corrosion behavior of Mg–Zn–Ca bulk metallic glass for biomedical applications
journal, December 2015
- Ramya, M.; Sarwat, Syed Ghazi; Udhayabanu, V.
- Materials & Design, Vol. 86
Cytotoxicity of zinc in vitro
journal, January 1989
- Borovanský, Jan; Riley, Patrick A.
- Chemico-Biological Interactions, Vol. 69, Issue 2-3
Effects of secondary phase and grain size on the corrosion of biodegradable Mg–Zn–Ca alloys
journal, March 2015
- Lu, Y.; Bradshaw, A. R.; Chiu, Y. L.
- Materials Science and Engineering: C, Vol. 48
MgZnCa glasses without clinically observable hydrogen evolution for biodegradable implants
journal, September 2009
- Zberg, Bruno; Uggowitzer, Peter J.; Löffler, Jörg F.
- Nature Materials, Vol. 8, Issue 11
Pd–Ni–Cu–P metallic glass nanowires for methanol and ethanol oxidation in alkaline media
journal, August 2013
- Sekol, Ryan C.; Carmo, Marcelo; Kumar, Golden
- International Journal of Hydrogen Energy, Vol. 38, Issue 26
Corrosion of, and cellular responses to Mg–Zn–Ca bulk metallic glasses
journal, February 2010
- Gu, Xuenan; Zheng, Yufeng; Zhong, Shengping
- Biomaterials, Vol. 31, Issue 6
The effect of zinc on the biocompatibility of dental amalgams in vitro
journal, September 1984
- Meryon, S. D.
- Biomaterials, Vol. 5, Issue 5
Combinatorial development of bulk metallic glasses
journal, April 2014
- Ding, Shiyan; Liu, Yanhui; Li, Yanglin
- Nature Materials, Vol. 13, Issue 5
Mg-based bulk metallic glasses for biodegradable implant materials: A review on glass forming ability, mechanical properties, and biocompatibility
journal, October 2015
- Dambatta, M. S.; Izman, S.; Yahaya, B.
- Journal of Non-Crystalline Solids, Vol. 426
Mechanical properties, degradation performance and cytotoxicity of Mg–Zn–Ca biomedical alloys with different compositions
journal, December 2011
- Zhang, Baoping; Hou, Yunlong; Wang, Xiaodan
- Materials Science and Engineering: C, Vol. 31, Issue 8
In vitro degradation and electrochemical corrosion evaluations of microarc oxidized pure Mg, Mg–Ca and Mg–Ca–Zn alloys for biomedical applications
journal, February 2015
- Pan, Yaokun; He, Siyu; Wang, Diangang
- Materials Science and Engineering: C, Vol. 47
Effects of Zn on the microstructure, mechanical property and bio-corrosion property of Mg–3Ca alloys for biomedical application
journal, February 2011
- Du, Hui; Wei, Zunjie; Liu, Xinwang
- Materials Chemistry and Physics, Vol. 125, Issue 3
In-vitro evaluation of Mg-4.0Zn-0.2Ca alloy for biomedical application
journal, August 2011
- Sun, Yu; Kong, Min-xiu; Jiao, Xiao-hui
- Transactions of Nonferrous Metals Society of China, Vol. 21
Biocompatibility of a novel zinc stent with a closed-cell-design
journal, September 2015
- Hiebl, Bernhard; Nennig, Ernst; Schiestel, Stefanie
- Clinical Hemorheology and Microcirculation, Vol. 61, Issue 2
Guided Evolution of Bulk Metallic Glass Nanostructures: A Platform for Designing 3D Electrocatalytic Surfaces
journal, December 2015
- Doubek, Gustavo; Sekol, Ryan C.; Li, Jinyang
- Advanced Materials, Vol. 28, Issue 10
Corrosion and related mechanical properties of bulk metallic glasses
journal, September 2006
- Scully, John R.; Gebert, A.; Payer, Joe H.
- Journal of Materials Research, Vol. 22, Issue 2
Combinatorial screening of Pd-based quaternary electrocatalysts for oxygen reduction reaction in alkaline media
journal, January 2017
- Li, Jinyang; Stein, Helge S.; Sliozberg, Kirill
- Journal of Materials Chemistry A, Vol. 5, Issue 1
Preparation and characterization of a new biomedical Mg–Zn–Ca alloy
journal, February 2012
- Sun, Yu; Zhang, Baoping; Wang, Yin
- Materials & Design, Vol. 34
Glass forming ability and thermal stability of ternary Ca–Mg–Zn bulk metallic glasses
journal, October 2005
- Senkov, O. N.; Scott, J. M.
- Journal of Non-Crystalline Solids, Vol. 351, Issue 37-39
Examining the elemental contribution towards the biodegradation of Mg–Zn–Ca ternary metallic glasses
journal, January 2016
- Miskovic, D. M.; Pohl, K.; Birbilis, N.
- Journal of Materials Chemistry B, Vol. 4, Issue 15
Metallic glass nanostructures of tunable shape and composition
journal, April 2015
- Liu, Yanhui; Liu, Jingbei; Sohn, Sungwoo
- Nature Communications, Vol. 6, Issue 1
Preparation and in vitro degradation of the composite coating with high adhesion strength on biodegradable Mg–Zn–Ca alloy
journal, December 2011
- Li, Wen; Guan, Shaokang; Chen, Juan
- Materials Characterization, Vol. 62, Issue 12
Influence of Ca and Zn on the microstructure and corrosion of biodegradable Mg–Ca–Zn alloys
journal, April 2015
- Zander, Daniela; Zumdick, Naemi A.
- Corrosion Science, Vol. 93
Improved mechanical performance and delayed corrosion phenomena in biodegradable Mg–Zn–Ca alloys through Pd-alloying
journal, February 2012
- González, S.; Pellicer, E.; Fornell, J.
- Journal of the Mechanical Behavior of Biomedical Materials, Vol. 6
Potentiodynamic polarisation study of bulk metallic glasses based on the Mg–Zn–Ca ternary system
journal, August 2012
- Cao, J. D.; Laws, K. J.; Birbilis, N.
- Corrosion Engineering, Science and Technology, Vol. 47, Issue 5
Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation
journal, September 2011
- Vojtěch, D.; Kubásek, J.; Šerák, J.
- Acta Biomaterialia, Vol. 7, Issue 9
Recent advances in bulk metallic glasses for biomedical applications
journal, May 2016
- Li, H. F.; Zheng, Y. F.
- Acta Biomaterialia, Vol. 36
Metallic glass thin films for potential biomedical applications: Metallic Glass Thin Films For Potential Biomedical Applications
journal, March 2014
- Kaushik, Neelam; Sharma, Parmanand; Ahadian, Samad
- Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 102, Issue 7
Biodegradable CaMgZn bulk metallic glass for potential skeletal application
journal, August 2011
- Wang, Y. B.; Xie, X. H.; Li, H. F.
- Acta Biomaterialia, Vol. 7, Issue 8
In vitro and in vivo corrosion measurements of magnesium alloys
journal, March 2006
- Witte, Frank; Fischer, Jens; Nellesen, Jens
- Biomaterials, Vol. 27, Issue 7
Opportunities and challenges for the biodegradable magnesium alloys as next-generation biomaterials
journal, March 2016
- Ding, Wenjiang
- Regenerative Biomaterials, Vol. 3, Issue 2
Microstructure and bio-corrosion behavior of Mg-Zn and Mg-Zn-Ca alloys for biomedical applications: Microstructure and bio-corrosion behavior of Mg-Zn and Mg-Zn-Ca alloys
journal, March 2014
- Bakhsheshi-Rad, H. R.; Hamzah, E.; Fereidouni-Lotfabadi, A.
- Materials and Corrosion, Vol. 65, Issue 12
Processing of Bulk Metallic Glass
journal, December 2009
- Schroers, Jan
- Advanced Materials, Vol. 22, Issue 14
Solidification of Au-Cu-Si alloys investigated by a combinatorial approach
journal, June 2012
- Ding, Shiyan; Gregoire, John; Vlassak, Joost J.
- Journal of Applied Physics, Vol. 111, Issue 11
Bulk Metallic Glass Nanowire Architecture for Electrochemical Applications
journal, March 2011
- Carmo, Marcelo; Sekol, Ryan C.; Ding, Shiyan
- ACS Nano, Vol. 5, Issue 4
Dissolution and precipitation behaviors of silicon-containing ceramic coating on Mg–Zn–Ca alloy in simulated body fluid
journal, October 2014
- Pan, Yaokun; Chen, Chuanzhong; Wang, Diangang
- Colloids and Surfaces B: Biointerfaces, Vol. 122
Relationship between the corrosion behavior and the thermal characteristics and microstructure of Mg–0.5Ca–xZn alloys
journal, November 2012
- Bakhsheshi-Rad, H. R.; Abdul-Kadir, M. R.; Idris, M. H.
- Corrosion Science, Vol. 64
Crystallization behavior upon heating and cooling in Cu50Zr50 metallic glass thin films
journal, December 2016
- Lee, Dongwoo; Zhao, Bingge; Perim, Eric
- Acta Materialia, Vol. 121
Corrosion Resistance of Ag-ion Implanted Mg-Ca-Zn Alloys in SBF
journal, December 2010
- Lihe, Mao; Yulin, Wang; Yizao, Wan
- Rare Metal Materials and Engineering, Vol. 39, Issue 12
Bulk Metallic Glass Micro Fuel Cell
journal, November 2012
- Sekol, Ryan C.; Kumar, Golden; Carmo, Marcelo
- Small, Vol. 9, Issue 12
In vitro corrosion behaviors of Mg67Zn28Ca5 alloy: From amorphous to crystalline
journal, June 2012
- Wang, Yongsheng; Tan, Ming Jen; Pang, Jianjun
- Materials Chemistry and Physics, Vol. 134, Issue 2-3
Ca–Mg–Zn bulk metallic glasses as bioresorbable metals
journal, July 2012
- Cao, J. D.; Kirkland, N. T.; Laws, K. J.
- Acta Biomaterialia, Vol. 8, Issue 6
Combinatorial exploration of color in gold-based alloys
journal, August 2015
- Liu, Jingbei; Liu, Yanhui; Gong, Pan
- Gold Bulletin, Vol. 48, Issue 3-4
Works referencing / citing this record:
Recent Advances in Metallic Glass Nanostructures: Synthesis Strategies and Electrocatalytic Applications
journal, December 2018
- Li, Jinyang; Doubek, Gustavo; McMillon-Brown, Lyndsey
- Advanced Materials, Vol. 31, Issue 7
Formation and stability of complex metallic phases including quasicrystals explored through combinatorial methods
journal, May 2019
- Wolf, Witor; Kube, Sebastian A.; Sohn, Sungwoo
- Scientific Reports, Vol. 9, Issue 1
Accelerated discovery and mechanical property characterization of bioresorbable amorphous alloys in the Mg–Zn–Ca and the Fe–Mg–Zn systems using high-throughput methods
journal, January 2019
- Datye, Amit; Alexander Kube, Sebastian; Verma, Devendra
- Journal of Materials Chemistry B, Vol. 7, Issue 35
Review on Quantum Mechanically Guided Design of Ultra-Strong Metallic Glasses
journal, April 2020
- Evertz, Simon; Schnabel, Volker; Köhler, Mathias
- Frontiers in Materials, Vol. 7
Review on Quantum Mechanically Guided Design of Ultra-Strong Metallic Glasses
text, January 2020
- Evertz, Simon; Schnabel, Volker; Köhler, Mathias
- RWTH Aachen University
Formation and stability of complex metallic phases including quasicrystals explored through combinatorial methods
journal, May 2019
- Wolf, Witor; Kube, Sebastian A.; Sohn, Sungwoo
- Scientific Reports, Vol. 9, Issue 1