Dynamic assembly of polymer nanotube networks via kinesin powered microtubule filaments
Abstract
In this study, we describe for the first time how biological nanomotors may be used to actively self-assemble mesoscale networks composed of diblock copolymer nanotubes. The collective force generated by multiple kinesin nanomotors acting on a microtubule filament is large enough to overcome the energy barrier required to extract nanotubes from polymer vesicles comprised of poly(ethylene oxide-b-butadiene) in spite of the higher force requirements relative to extracting nanotubes from lipid vesicles. Nevertheless, large-scale polymer networks were dynamically assembled by the motors. These networks displayed enhanced robustness, persisting more than 24 h post-assembly (compared to 4–5 h for corresponding lipid networks). The transport of materials in and on the polymer membranes differs substantially from the transport on analogous lipid networks. Specifically, our data suggest that polymer mobility in nanotubular structures is considerably different from planar or 3D structures, and is stunted by 1D confinement of the polymer subunits. Moreover, quantum dots adsorbed onto polymer nanotubes are completely immobile, which is related to this 1D confinement effect and is in stark contrast to the highly fluid transport observed on lipid tubules.
- Authors:
-
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Publication Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1235363
- Report Number(s):
- SAND-2015-0605J
Journal ID: ISSN 2040-3364; NANOHL; 562487
- Grant/Contract Number:
- AC04-94AL85000
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Nanoscale
- Additional Journal Information:
- Journal Volume: 7; Journal Issue: 25; Journal ID: ISSN 2040-3364
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 77 NANOSCIENCE AND NANOTECHNOLOGY
Citation Formats
Paxton, Walter F., Bachand, George D., Gomez, Andrew, Henderson, Ian M., and Bouxsein, Nathan F. Dynamic assembly of polymer nanotube networks via kinesin powered microtubule filaments. United States: N. p., 2015.
Web. doi:10.1039/C5NR00826C.
Paxton, Walter F., Bachand, George D., Gomez, Andrew, Henderson, Ian M., & Bouxsein, Nathan F. Dynamic assembly of polymer nanotube networks via kinesin powered microtubule filaments. United States. https://doi.org/10.1039/C5NR00826C
Paxton, Walter F., Bachand, George D., Gomez, Andrew, Henderson, Ian M., and Bouxsein, Nathan F. Fri .
"Dynamic assembly of polymer nanotube networks via kinesin powered microtubule filaments". United States. https://doi.org/10.1039/C5NR00826C. https://www.osti.gov/servlets/purl/1235363.
@article{osti_1235363,
title = {Dynamic assembly of polymer nanotube networks via kinesin powered microtubule filaments},
author = {Paxton, Walter F. and Bachand, George D. and Gomez, Andrew and Henderson, Ian M. and Bouxsein, Nathan F.},
abstractNote = {In this study, we describe for the first time how biological nanomotors may be used to actively self-assemble mesoscale networks composed of diblock copolymer nanotubes. The collective force generated by multiple kinesin nanomotors acting on a microtubule filament is large enough to overcome the energy barrier required to extract nanotubes from polymer vesicles comprised of poly(ethylene oxide-b-butadiene) in spite of the higher force requirements relative to extracting nanotubes from lipid vesicles. Nevertheless, large-scale polymer networks were dynamically assembled by the motors. These networks displayed enhanced robustness, persisting more than 24 h post-assembly (compared to 4–5 h for corresponding lipid networks). The transport of materials in and on the polymer membranes differs substantially from the transport on analogous lipid networks. Specifically, our data suggest that polymer mobility in nanotubular structures is considerably different from planar or 3D structures, and is stunted by 1D confinement of the polymer subunits. Moreover, quantum dots adsorbed onto polymer nanotubes are completely immobile, which is related to this 1D confinement effect and is in stark contrast to the highly fluid transport observed on lipid tubules.},
doi = {10.1039/C5NR00826C},
journal = {Nanoscale},
number = 25,
volume = 7,
place = {United States},
year = {Fri Apr 24 00:00:00 EDT 2015},
month = {Fri Apr 24 00:00:00 EDT 2015}
}
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