Plasmonic nanorod probes’ journey inside plant cells for in vivo SERS sensing and multimodal imaging
Abstract
Nanoparticle-based platforms are gaining strong interest in plant biology and bioenergy research to monitor and control biological processes in whole plants. However, in vivo monitoring of biomolecules using nanoparticles inside plant cells remains challenging due to the impenetrability of the plant cell wall to nanoparticles beyond the exclusion limits (5–20 nm). To overcome this physical barrier, we have designed unique bimetallic silver-coated gold nanorods (AuNR@Ag) capable of entering plant cells, while conserving key plasmonic properties in the near-infrared (NIR). To demonstrate cellular internalization and tracking of the nanorods inside plant tissue, we used a comprehensive multimodal imaging approach that included transmission electron microscopy (TEM), confocal fluorescence microscopy, two-photon luminescence (TPL), X-ray fluorescence microscopy (XRF), and photoacoustics imaging (PAI). We successfully acquired SERS signals of nanorods in vivo inside plant cells of tobacco leaves. On the same leaf samples, we applied orthogonal imaging methods, TPL and PAI techniques for in vivo imaging of the nanorods. Here this study first demonstrates the intracellular internalization of AuNR@Ag inside whole plant systems for in vivo SERS analysis in tobacco cells. This work demonstrates the potential of this nanoplatform as a new nanotool for intracellular in vivo biosensing for plant biology.
- Authors:
-
[1];
[1];
[1]
- Fitzpatrick Institute for Photonics, Durham, NC (United States); Duke University, Durham, NC (United States)
- Fitzpatrick Institute for Photonics, Durham, NC (United States)
- Duke University, Durham, NC (United States)
- Bulgarian Academy of Sciences, Sofia (Bulgaria); Argonne National Laboratory (ANL), Argonne, IL (United States)
- Argonne National Laboratory (ANL), Lemont, IL (United States)
- Argonne National Laboratory (ANL), Lemont, IL (United States); Northwestern University, Evanston, IL (United States)
- Publication Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC); National Science Foundation (NSF); Fitzpatrick Foundation Scholars Award; NDSEG Fellowship
- OSTI Identifier:
- 1970364
- Alternate Identifier(s):
- OSTI ID: 1961899
- Grant/Contract Number:
- AC02-06CH11357; ECCS-2025064; SC0019393
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Nanoscale
- Additional Journal Information:
- Journal Volume: 15; Journal Issue: 13; Journal ID: ISSN 2040-3364
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 77 NANOSCIENCE AND NANOTECHNOLOGY; plasmonics; surface-enhanced Raman scattering; cell; infiltration; plants; nanorods; nanosensor
Citation Formats
Cupil-Garcia, Vanessa, Li, Joy Q., Norton, Stephen J., Odion, Ren A., Strobbia, Pietro, Menozzi, Luca, Ma, Chenshuo, Hu, Jianhong, Zentella, Rodolfo, Boyanov, Maxim I., Finfrock, Y. Zou, Gursoy, Doga, Douglas, Deirdre Sholto, Yao, Junjie, Sun, Tai-Ping, Kemner, Kenneth M., and Vo-Dinh, Tuan. Plasmonic nanorod probes’ journey inside plant cells for in vivo SERS sensing and multimodal imaging. United States: N. p., 2023.
Web. doi:10.1039/d2nr06235f.
Cupil-Garcia, Vanessa, Li, Joy Q., Norton, Stephen J., Odion, Ren A., Strobbia, Pietro, Menozzi, Luca, Ma, Chenshuo, Hu, Jianhong, Zentella, Rodolfo, Boyanov, Maxim I., Finfrock, Y. Zou, Gursoy, Doga, Douglas, Deirdre Sholto, Yao, Junjie, Sun, Tai-Ping, Kemner, Kenneth M., & Vo-Dinh, Tuan. Plasmonic nanorod probes’ journey inside plant cells for in vivo SERS sensing and multimodal imaging. United States. https://doi.org/10.1039/d2nr06235f
Cupil-Garcia, Vanessa, Li, Joy Q., Norton, Stephen J., Odion, Ren A., Strobbia, Pietro, Menozzi, Luca, Ma, Chenshuo, Hu, Jianhong, Zentella, Rodolfo, Boyanov, Maxim I., Finfrock, Y. Zou, Gursoy, Doga, Douglas, Deirdre Sholto, Yao, Junjie, Sun, Tai-Ping, Kemner, Kenneth M., and Vo-Dinh, Tuan. Mon .
"Plasmonic nanorod probes’ journey inside plant cells for in vivo SERS sensing and multimodal imaging". United States. https://doi.org/10.1039/d2nr06235f. https://www.osti.gov/servlets/purl/1970364.
@article{osti_1970364,
title = {Plasmonic nanorod probes’ journey inside plant cells for in vivo SERS sensing and multimodal imaging},
author = {Cupil-Garcia, Vanessa and Li, Joy Q. and Norton, Stephen J. and Odion, Ren A. and Strobbia, Pietro and Menozzi, Luca and Ma, Chenshuo and Hu, Jianhong and Zentella, Rodolfo and Boyanov, Maxim I. and Finfrock, Y. Zou and Gursoy, Doga and Douglas, Deirdre Sholto and Yao, Junjie and Sun, Tai-Ping and Kemner, Kenneth M. and Vo-Dinh, Tuan},
abstractNote = {Nanoparticle-based platforms are gaining strong interest in plant biology and bioenergy research to monitor and control biological processes in whole plants. However, in vivo monitoring of biomolecules using nanoparticles inside plant cells remains challenging due to the impenetrability of the plant cell wall to nanoparticles beyond the exclusion limits (5–20 nm). To overcome this physical barrier, we have designed unique bimetallic silver-coated gold nanorods (AuNR@Ag) capable of entering plant cells, while conserving key plasmonic properties in the near-infrared (NIR). To demonstrate cellular internalization and tracking of the nanorods inside plant tissue, we used a comprehensive multimodal imaging approach that included transmission electron microscopy (TEM), confocal fluorescence microscopy, two-photon luminescence (TPL), X-ray fluorescence microscopy (XRF), and photoacoustics imaging (PAI). We successfully acquired SERS signals of nanorods in vivo inside plant cells of tobacco leaves. On the same leaf samples, we applied orthogonal imaging methods, TPL and PAI techniques for in vivo imaging of the nanorods. Here this study first demonstrates the intracellular internalization of AuNR@Ag inside whole plant systems for in vivo SERS analysis in tobacco cells. This work demonstrates the potential of this nanoplatform as a new nanotool for intracellular in vivo biosensing for plant biology.},
doi = {10.1039/d2nr06235f},
journal = {Nanoscale},
number = 13,
volume = 15,
place = {United States},
year = {Mon Mar 13 00:00:00 EDT 2023},
month = {Mon Mar 13 00:00:00 EDT 2023}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Application of Synchrotron X-ray Absorption Spectroscopy and Microscopy Techniques to the Study of Biogeochemical Processes
book, July 2019
- Boyanov, Maxim I.; Kemner, Kenneth M.
- Analytical Geomicrobiology
Surface raman spectroelectrochemistry: Part I. Heterocyclic, aromatic, and aliphatic amines adsorbed on the anodized silver electrode
journal, November 1977
- Jeanmaire, David L.; Van Duyne, Richard P.
- Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, Vol. 84, Issue 1, p. 1-20
Effect of Nanoparticles on the Cell Life Cycle
journal, March 2011
- Mahmoudi, Morteza; Azadmanesh, Kayhan; Shokrgozar, Mohammad A.
- Chemical Reviews, Vol. 111, Issue 5
Contrast agents for molecular photoacoustic imaging
journal, July 2016
- Weber, Judith; Beard, Paul C.; Bohndiek, Sarah E.
- Nature Methods, Vol. 13, Issue 8
Photothermal ablation of inflammatory breast cancer tumor emboli using plasmonic gold nanostars
journal, August 2017
- Crawford, Bridget; Shammas, Ronnie; Fales, Andrew
- International Journal of Nanomedicine, Vol. Volume 12
Detection of Polycyclic Aromatic Compounds in Single Living Cells Using Optical Nanoprobes
journal, June 2004
- Kasili, Paul M.; Vo-Dinh, Tuan
- Polycyclic Aromatic Compounds, Vol. 24, Issue 3
DNA nanostructures coordinate gene silencing in mature plants
journal, March 2019
- Zhang, Huan; Demirer, Gozde S.; Zhang, Honglu
- Proceedings of the National Academy of Sciences, Vol. 116, Issue 15
Ultra-high SERS detection of consumable coloring agents using plasmonic gold nanostars with high aspect-ratio spikes
journal, January 2022
- Atta, Supriya; Watcharawittayakul, Tongchatra; Vo-Dinh, Tuan
- The Analyst, Vol. 147, Issue 14
Raman spectra of pyridine adsorbed at a silver electrode
journal, May 1974
- Fleischmann, M.; Hendra, P. J.; McQuillan, A. J.
- Chemical Physics Letters, Vol. 26, Issue 2, p. 163-166
Gold nanoparticles for photoacoustic imaging
journal, January 2015
- Li, Wanwan; Chen, Xiaoyuan
- Nanomedicine, Vol. 10, Issue 2
Elemental and Redox Analysis of Single Bacterial Cells by X-ray Microbeam Analysis
journal, October 2004
- Kemner, K. M.
- Science, Vol. 306, Issue 5696
Magnetic gold nanoparticles as a vehicle for fluorescein isothiocyanate and DNA delivery into plant cells
journal, July 2013
- Hao, Yuzhi; Yang, Xiaoyan; Shi, Yongzhong
- Botany, Vol. 91, Issue 7
On the use of Au@Ag core-shell nanorods for SERS detection of Thiram diluted solutions
journal, April 2020
- Pastorello, Murilo; Sigoli, Fernando A.; dos Santos, Diego P.
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Vol. 231
Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein for Efficient Gene Editing
journal, January 2017
- Mout, Rubul; Ray, Moumita; Yesilbag Tonga, Gulen
- ACS Nano, Vol. 11, Issue 3
Plasmonic Nanoprobes for in Vivo Multimodal Sensing and Bioimaging of MicroRNA within Plants
journal, January 2019
- Crawford, Bridget M.; Strobbia, Pietro; Wang, Hsin-Neng
- ACS Applied Materials & Interfaces, Vol. 11, Issue 8
Photoacoustic imaging in biomedicine
journal, April 2006
- Xu, Minghua; Wang, Lihong V.
- Review of Scientific Instruments, Vol. 77, Issue 4
A practical guide to photoacoustic tomography in the life sciences
journal, July 2016
- Wang, Lihong V.; Yao, Junjie
- Nature Methods, Vol. 13, Issue 8
Nanosensor for In Vivo Measurement of the Carcinogen Benzo[a]pyrene in a Single Cell
journal, December 2002
- Kasili, P. M.; Cullum, B. M.; Griffin, G. D.
- Journal of Nanoscience and Nanotechnology, Vol. 2, Issue 6
Inverse Molecular Sentinel-Integrated Fiberoptic Sensor for Direct and in Situ Detection of miRNA Targets
journal, March 2019
- Strobbia, Pietro; Ran, Yang; Crawford, Bridget M.
- Analytical Chemistry, Vol. 91, Issue 9
Nanotechnology in Plant Science: To Make a Long Story Short
journal, May 2019
- Sanzari, Ilaria; Leone, Antonietta; Ambrosone, Alfredo
- Frontiers in Bioengineering and Biotechnology, Vol. 7
Nanoparticle cellular internalization is not required for RNA delivery to mature plant leaves
journal, November 2021
- Zhang, Huan; Goh, Natalie S.; Wang, Jeffrey W.
- Nature Nanotechnology, Vol. 17, Issue 2
Delivery, Fate, and Mobility of Silver Nanoparticles in Citrus Trees
journal, March 2020
- Su, Yiming; Ashworth, Vanessa E. T. M.; Geitner, Nicholas K.
- ACS Nano, Vol. 14, Issue 3
Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics
journal, January 2013
- Liu, Yang; Chang, Zheng; Yuan, Hsiangkuo
- Nanoscale, Vol. 5, Issue 24
Present and Future of Surface-Enhanced Raman Scattering
journal, September 2019
- Langer, Judith; Jimenez de Aberasturi, Dorleta; Aizpurua, Javier
- ACS Nano, Vol. 14, Issue 1
Antibody-based nanoprobe for measurement of a fluorescent analyte in a single cell
journal, July 2000
- Vo-Dinh, Tuan; Alarie, Jean-Pierre; Cullum, Brian M.
- Nature Biotechnology, Vol. 18, Issue 7
Development of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced Raman Scattering
journal, February 2014
- Fales, Andrew M.; Yuan, Hsiangkuo; Vo-Dinh, Tuan
- The Journal of Physical Chemistry C, Vol. 118, Issue 7
Sensitive DNA detection and SNP discrimination using ultrabright SERS nanorattles and magnetic beads for malaria diagnostics
journal, July 2016
- Ngo, Hoan T.; Gandra, Naveen; Fales, Andrew M.
- Biosensors and Bioelectronics, Vol. 81
The MRCAT insertion device beamline at the Advanced Photon Source
conference, January 2000
- Segre, C. U.
- The 11th US national synchrotron radiation instrumentation conference (SRI99), AIP Conference Proceedings
Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants – Critical review
journal, June 2015
- Schwab, Fabienne; Zhai, Guangshu; Kern, Meaghan
- Nanotoxicology, Vol. 10, Issue 3
Size exclusion limits and lateral heterogeneity of the stomatal foliar uptake pathway for aqueous solutes and water-suspended nanoparticles
journal, September 2008
- Eichert, Thomas; Kurtz, Andreas; Steiner, Ulrike
- Physiologia Plantarum, Vol. 134, Issue 1
The brightest colors: A Fourier‐transform Raman, surface‐enhanced Raman, and thin‐layer chromatography‐surface‐enhanced Raman spectroscopy study of fluorescent artists' paints
journal, March 2020
- Boscacci, Maddalena; Francone, Serena; Galli, Katia
- Journal of Raman Spectroscopy, Vol. 51, Issue 7
Nano and Plants
journal, February 2022
- Buriak, Jillian M.; Liz-Marzán, Luis M.; Parak, Wolfgang J.
- ACS Nano, Vol. 16, Issue 2
Anomalously intense Raman spectra of pyridine at a silver electrode
journal, June 1977
- Albrecht, M. Grant; Creighton, J. Alan
- Journal of the American Chemical Society, Vol. 99, Issue 15
Effect of surface plasmons on transitions in molecules
journal, March 1975
- Philpott, Michael R.
- The Journal of Chemical Physics, Vol. 62, Issue 5
Gold Nanoparticles Are Taken Up by Human Cells but Do Not Cause Acute Cytotoxicity
journal, March 2005
- Connor, Ellen E.; Mwamuka, Judith; Gole, Anand
- Small, Vol. 1, Issue 3, p. 325-327
Parameters Affecting the Efficient Delivery of Mesoporous Silica Nanoparticle Materials and Gold Nanorods into Plant Tissues by the Biolistic Method
journal, December 2011
- Martin-Ortigosa, Susana; Valenstein, Justin S.; Sun, Wei
- Small, Vol. 8, Issue 3
Nanoparticle-Mediated Delivery towards Advancing Plant Genetic Engineering
journal, September 2018
- Cunningham, Francis J.; Goh, Natalie S.; Demirer, Gozde S.
- Trends in Biotechnology, Vol. 36, Issue 9
Germanium collimating micro-channel arrays for high resolution, high energy confocal X-ray fluorescence microscopy
conference, January 2016
- Agyeman-Budu, David N.; Choudhury, Sanjukta; Coulthard, Ian
- ICXOM23: International Conference on X-ray Optics and Microanalysis, AIP Conference Proceedings
High aspect ratio nanomaterials enable delivery of functional genetic material without DNA integration in mature plants
journal, February 2019
- Demirer, Gozde S.; Zhang, Huan; Matos, Juliana L.
- Nature Nanotechnology, Vol. 14, Issue 5
Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the Treatment of Unresectable and Metastatic Cancers
journal, August 2017
- Liu, Yang; Maccarini, Paolo; Palmer, Gregory M.
- Scientific Reports, Vol. 7, Issue 1
Nanotechnology: A New Opportunity in Plant Sciences
journal, August 2016
- Wang, Peng; Lombi, Enzo; Zhao, Fang-Jie
- Trends in Plant Science, Vol. 21, Issue 8
In vivo surface-enhanced Raman scattering nanosensor for the real-time monitoring of multiple stress signalling molecules in plants
journal, December 2022
- Son, Won Ki; Choi, Yun Sik; Han, Young Woo
- Nature Nanotechnology, Vol. 18, Issue 2
Survey over image thresholding techniques and quantitative performance evaluation
journal, January 2004
- Sankur, Bu¨lent
- Journal of Electronic Imaging, Vol. 13, Issue 1
Sensing Glucose in Urine and Serum and Hydrogen Peroxide in Living Cells by Use of a Novel Boronate Nanoprobe Based on Surface-Enhanced Raman Spectroscopy
journal, July 2016
- Gu, Xin; Wang, Hao; Schultz, Zachary D.
- Analytical Chemistry, Vol. 88, Issue 14
Effect of Surface Charge on the Uptake and Distribution of Gold Nanoparticles in Four Plant Species
journal, November 2012
- Zhu, Zheng-Jiang; Wang, Huanhua; Yan, Bo
- Environmental Science & Technology, Vol. 46, Issue 22
Gold-Nanocluster-Mediated Delivery of siRNA to Intact Plant Cells for Efficient Gene Knockdown
journal, June 2021
- Zhang, Huan; Cao, Yuhong; Xu, Dawei
- Nano Letters, Vol. 21, Issue 13
XAFS at the Pacific Northwest Consortium-Collaborative Access Team undulator beamline
journal, March 2001
- Heald, Steve; Stern, Edward; Brewe, Dale
- Journal of Synchrotron Radiation, Vol. 8, Issue 2
The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems
journal, August 2012
- Albanese, Alexandre; Tang, Peter S.; Chan, Warren C. W.
- Annual Review of Biomedical Engineering, Vol. 14, Issue 1
Integration of Agrobacterium T-DNA into the Plant Genome
journal, November 2017
- Gelvin, Stanton B.
- Annual Review of Genetics, Vol. 51, Issue 1
Catching COVID: Engineering Peptide-Modified Surface-Enhanced Raman Spectroscopy Sensors for SARS-CoV-2
journal, September 2021
- Payne, Taylor D.; Klawa, Stephen J.; Jian, Tengyue
- ACS Sensors, Vol. 6, Issue 9
GFP for in vivo imaging of subcellular structures in plant cells
journal, August 1998
- Köhler, Rainer H.
- Trends in Plant Science, Vol. 3, Issue 8
Uptake, distribution and toxicity of gold nanoparticles in tobacco ( Nicotiana xanthi ) seedlings
journal, May 2011
- Sabo-Attwood, Tara; Unrine, Jason M.; Stone, John W.
- Nanotoxicology, Vol. 6, Issue 4
Fiji: an open-source platform for biological-image analysis
journal, June 2012
- Schindelin, Johannes; Arganda-Carreras, Ignacio; Frise, Erwin
- Nature Methods, Vol. 9, Issue 7
Surface roughness and the enhanced intensity of Raman scattering by molecules adsorbed on metals
journal, November 1978
- Moskovits, M.
- The Journal of Chemical Physics, Vol. 69, Issue 9
Nanoparticles and their applications in cell and molecular biology
journal, October 2013
- Wang, Edina C.; Wang, Andrew Z.
- Integrative Biology, Vol. 6, Issue 1
MiR397b regulates both lignin content and seed number in Arabidopsis via modulating a laccase involved in lignin biosynthesis
journal, June 2014
- Wang, Cong-Ying; Zhang, Shengchun; Yu, Yang
- Plant Biotechnology Journal, Vol. 12, Issue 8
Nanoparticles for photoacoustic imaging: Nanoparticles for photoacoustic imaging
journal, May 2009
- Yang, Xinmai; Stein, Erich W.; Ashkenazi, S.
- Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Vol. 1, Issue 4
SCARECROW-LIKE 3 promotes gibberellin signaling by antagonizing master growth repressor DELLA in Arabidopsis
journal, January 2011
- Zhang, Zhong-Lin; Ogawa, Mikihiro; Fleet, Christine M.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 5
Plasmonic nanoplatforms: From surface‐enhanced Raman scattering sensing to biomedical applications
journal, December 2020
- Cupil‐Garcia, Vanessa; Strobbia, Pietro; Crawford, Bridget M.
- Journal of Raman Spectroscopy, Vol. 52, Issue 2
Bioenergy: Challenges Ahead and Future
book, January 2023
- Kaur, Sandeep; Sarao, Loveleen Kaur
- Clean Energy Production Technologies
Cellular uptake of nanoparticles: journey inside the cell
journal, January 2017
- Behzadi, Shahed; Serpooshan, Vahid; Tao, Wei
- Chemical Society Reviews, Vol. 46, Issue 14
Nanoparticle Size and Coating Chemistry Control Foliar Uptake Pathways, Translocation, and Leaf-to-Rhizosphere Transport in Wheat
journal, April 2019
- Avellan, Astrid; Yun, Jie; Zhang, Yilin
- ACS Nano, Vol. 13, Issue 5
Optical Nanobiosensor for Monitoring an Apoptotic Signaling Process in a Single Living Cell Following Photodynamic Therapy
journal, December 2005
- Kasili, PaulM.; Vo-Dinh, Tuan
- Journal of Nanoscience and Nanotechnology, Vol. 5, Issue 12
Dual functions of gold nanorods as photothermal agent and autofluorescence enhancer to track cell death during plasmonic photothermal therapy
journal, February 2015
- Kannadorai, Ravi Kumar; Chiew, Geraldine Giap Ying; Luo, Kathy Qian
- Cancer Letters, Vol. 357, Issue 1
Shiga Toxin-B Targeted Gold Nanorods for Local Photothermal Treatment in Oral Cancer Clinical Samples
journal, November 2022
- Navarro-Palomares, Elena; García-Hevia, Lorena; Galán-Vidal, Jesús
- International Journal of Nanomedicine, Vol. Volume 17
Surface-enhanced Raman spectroscopy using metallic nanostructures1The submitted manuscript has been authored by a contractor of the U.S Government under contract No. DE-AC05-96OR22464. Accordingly, the U.S. Government retains a nonexclusive, royalty-free license to publish or reproduce the published form of this contribution, or allow others to do so, for U.S. Government purposes.1
journal, August 1998
- Vo-Dinh, Tuan
- TrAC Trends in Analytical Chemistry, Vol. 17, Issue 8-9
Differentiating gold nanorod samples using particle size and shape distributions from transmission electron microscope images
journal, February 2018
- Grulke, Eric A.; Wu, Xiaochun; Ji, Yinglu
- Metrologia, Vol. 55, Issue 2
Selectively Tracking Nanoparticles in Aquatic Plant Using Core–Shell Nanoparticle-Enhanced Raman Spectroscopy Imaging
journal, December 2021
- Yang, Chuan-Wang; Hu, Yi; Yuan, Li
- ACS Nano, Vol. 15, Issue 12
Simultaneous Raman and infrared spectroscopy: a novel combination for studying bacterial infections at the single cell level
journal, January 2022
- Lima, Cassio; Ahmed, Shwan; Xu, Yun
- Chemical Science, Vol. 13, Issue 27
Mesoporous silica nanoparticles deliver DNA and chemicals into plants
journal, April 2007
- Torney, François; Trewyn, Brian G.; Lin, Victor S. -Y.
- Nature Nanotechnology, Vol. 2, Issue 5
SERS-based plasmonic nanobiosensing in single living cells
journal, December 2008
- Scaffidi, Jonathan P.; Gregas, Molly K.; Seewaldt, Victoria
- Analytical and Bioanalytical Chemistry, Vol. 393, Issue 4
Nanoparticle Uptake in Plants: Gold Nanomaterial Localized in Roots of Arabidopsis thaliana by X-ray Computed Nanotomography and Hyperspectral Imaging
journal, July 2017
- Avellan, Astrid; Schwab, Fabienne; Masion, Armand
- Environmental Science & Technology, Vol. 51, Issue 15