Transforming biorefinery designs with ‘Plug-In Processes of Lignin’ to enable economic waste valorization

Liu, Zhi-Hua; Hao, Naijia; Wang, Yun-Yan; Dou, Chang; Lin, Furong; Shen, Rongchun; Bura, Renata; Hodge, David B.; Dale, Bruce E.; Ragauskas, Arthur J.; Yang, Bin; Yuan, Joshua S.

doi:10.1038/s41467-021-23920-4

Title: Transforming biorefinery designs with ‘Plug-In Processes of Lignin’ to enable economic waste valorization

Journal Article · Wed Jun 23 00:00:00 UTC 2021 · Nature Communications

DOI: https://doi.org/10.1038/s41467-021-23920-4 · OSTI ID:1814277

Liu, Zhi-Hua ^[1]; Hao, Naijia ^[2];

^[3]; Dou, Chang ^[4]; Lin, Furong ^[1]; Shen, Rongchun ^[5]; Bura, Renata ^[4]; Hodge, David B. ^[6]; Dale, Bruce E. ^[7];

^[3]; Yang, Bin ^[5];

^[1]

Texas A & M Univ., College Station, TX (United States)
Univ. of Tennessee, Knoxville, TN (United States)
Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Univ. of Washington, Seattle, WA (United States)
Washington State Univ., Pullman, WA (United States)
Montana State Univ., Bozeman, MT (United States)
Michigan State Univ., East Lansing, MI (United States)

Biological lignin valorization has emerged as a major solution for sustainable and cost-effective biorefineries. However, current biorefineries yield lignin with inadequate fractionation for bioconversion, yet substantial changes of these biorefinery designs to focus on lignin could jeopardize carbohydrate efficiency and increase capital costs. We resolve the dilemma by designing ‘plug-in processes of lignin’ with the integration of leading pretreatment technologies. Substantial improvement of lignin bioconversion and synergistic enhancement of carbohydrate processing are achieved by solubilizing lignin via lowering molecular weight and increasing hydrophilic groups, addressing the dilemma of lignin- or carbohydrate-first scenarios. The plug-in processes of lignin could enable minimum polyhydroxyalkanoate selling price at as low as $6.18/kg. The results highlight the potential to achieve commercial production of polyhydroxyalkanoates as a co-product of cellulosic ethanol. Here, we show that the plug-in processes of lignin could transform biorefinery design toward sustainability by promoting carbon efficiency and optimizing the total capital cost.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE Office of Energy Efficiency and Renewable Energy (EERE), Transportation Office. Bioenergy Technologies Office

Grant/Contract Number:: AC05-00OR22725; EE0006112; EE0007104; EE0008250

OSTI ID:: 1814277

Journal Information:: Nature Communications, Journal Name: Nature Communications Journal Issue: 1 Vol. 12; ISSN 2041-1723

Publisher:: Nature Publishing GroupCopyright Statement

Country of Publication:: United States

Language:: English

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Additional file 2 of Understanding of bacterial lignin extracellular degradation mechanisms by Pseudomonas putida KT2440 via secretomic analysis Xu, Zhangyang; Peng, Bo; Kitata, Reta Birhanu figshare https://doi.org/10.6084/m9.figshare.21443760.v1	dataset	January 2022

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