Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase
- Department of Chemistry, University of British Columbia, Vancouver BC, Canada V6T 1Z1
- Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver BC, Canada V6T 1Z3
Simplified analogues of montbretin A bind similarly to human alpha amylase and with nanomolar affinity.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 1572100
- Alternate ID(s):
- OSTI ID: 1624978
- Journal Information:
- Chemical Science, Journal Name: Chemical Science Journal Issue: 48 Vol. 10; ISSN 2041-6520; ISSN CSHCBM
- Publisher:
- Royal Society of Chemistry (RSC)Copyright Statement
- Country of Publication:
- United Kingdom
- Language:
- English
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