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Title: Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase

Journal Article · · Chemical Science
DOI: https://doi.org/10.1039/C9SC02610J · OSTI ID:1572100
 [1];  [2];  [1];  [1];  [2]; ORCiD logo [1]
  1. Department of Chemistry, University of British Columbia, Vancouver BC, Canada V6T 1Z1
  2. Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver BC, Canada V6T 1Z3

Simplified analogues of montbretin A bind similarly to human alpha amylase and with nanomolar affinity.

Sponsoring Organization:
USDOE
OSTI ID:
1572100
Alternate ID(s):
OSTI ID: 1624978
Journal Information:
Chemical Science, Journal Name: Chemical Science Journal Issue: 48 Vol. 10; ISSN 2041-6520; ISSN CSHCBM
Publisher:
Royal Society of Chemistry (RSC)Copyright Statement
Country of Publication:
United Kingdom
Language:
English

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