Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase
Abstract
Simplified analogues of montbretin A bind similarly to human alpha amylase and with nanomolar affinity.
- Authors:
-
[1]
- Department of Chemistry, University of British Columbia, Vancouver BC, Canada V6T 1Z1
- Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver BC, Canada V6T 1Z3
- Publication Date:
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1572100
- Resource Type:
- Published Article
- Journal Name:
- Chemical Science
- Additional Journal Information:
- Journal Name: Chemical Science Journal Volume: 10 Journal Issue: 48; Journal ID: ISSN 2041-6520
- Publisher:
- Royal Society of Chemistry (RSC)
- Country of Publication:
- United Kingdom
- Language:
- English
Citation Formats
Tysoe, Christina R., Caner, Sami, Calvert, Matthew B., Win-Mason, Anna, Brayer, Gary D., and Withers, Stephen G. Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase. United Kingdom: N. p., 2019.
Web. doi:10.1039/C9SC02610J.
Tysoe, Christina R., Caner, Sami, Calvert, Matthew B., Win-Mason, Anna, Brayer, Gary D., & Withers, Stephen G. Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase. United Kingdom. doi:10.1039/C9SC02610J.
Tysoe, Christina R., Caner, Sami, Calvert, Matthew B., Win-Mason, Anna, Brayer, Gary D., and Withers, Stephen G. Wed .
"Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase". United Kingdom. doi:10.1039/C9SC02610J.
@article{osti_1572100,
title = {Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase},
author = {Tysoe, Christina R. and Caner, Sami and Calvert, Matthew B. and Win-Mason, Anna and Brayer, Gary D. and Withers, Stephen G.},
abstractNote = {Simplified analogues of montbretin A bind similarly to human alpha amylase and with nanomolar affinity.},
doi = {10.1039/C9SC02610J},
journal = {Chemical Science},
number = 48,
volume = 10,
place = {United Kingdom},
year = {2019},
month = {12}
}
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Publisher's Version of Record
DOI: 10.1039/C9SC02610J
DOI: 10.1039/C9SC02610J
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