Potent Human α-Amylase Inhibition by the β-Defensin-like Protein Helianthamide

Journal Article · 25 February 2016 · ACS Central Science

DOI: https://doi.org/10.1021/acscentsci.5b00399 · OSTI ID:1239610

Tysoe, Christina ^[1]; Williams, Leslie K. ^[2]; Keyzers, Robert ^[3]; Nguyen, Nham T. ^[2]; Tarling, Chris ^[4]; Wicki, Jacqueline ^[4]; Goddard-Borger, Ethan D. ^[4]; Aguda, Adeleke H. ^[2]; Perry, Suzanne ^[1]; Foster, Leonard J. ^[1]; Andersen, Raymond J. ^[3]; Brayer, Gary D. ^[2]; Withers, Stephen G. ^[5]

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1. Centre for High-Throughput Biology, Michael Smith Laboratories, 185 East Mall, Vancouver, British Columbia V6T 1Z4, Canada
2. Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
3. Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada, Department of Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada
4. Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada
5. Centre for High-Throughput Biology, Michael Smith Laboratories, 185 East Mall, Vancouver, British Columbia V6T 1Z4, Canada, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada, Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada

Not Available

• Research Organization: SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States)
• Sponsoring Organization: USDOE Office of Science (SC), Basic Energy Sciences (BES); USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22); USDOE Office of Science (SC), Biological and Environmental Research (BER); USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
• Grant/Contract Number: AC02-76SF00515
• OSTI ID: 1239610
• Journal Information: ACS Central Science, Journal Name: ACS Central Science Journal Issue: 3 Vol. 2; ISSN 2374-7943
• Publisher: American Chemical SocietyCopyright Statement
• Country of Publication: United States
• Language: English