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Title: Novel Insights Into the Spread of Enteric Pathogens Using Genomics

Abstract

Diarrheal diseases continue to be a leading cause of mortality and morbidity across the globe. The use of next-generation sequencing data has provided major insights into understanding epidemiological spread, antimicrobial resistance, vaccine effects, and basic mechanisms of bacterial and viral evolution. Furthermore, we discuss how genomic data have informed investigations across enteric pathogens, such as Shigella, Vibrio cholerae, Salmonella Typhi, rotavirus, and norovirus.

Authors:
ORCiD logo [1];  [2];  [3]; ORCiD logo [1]; ORCiD logo [1]
  1. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
  2. Wellcome Sanger Institute, Hinxton (United Kingdom); Univ. of Cambridge, Cambridge (United Kingdom)
  3. Wellcome Sanger Institute, Hinxton (United Kingdom)
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE Laboratory Directed Research and Development (LDRD) Program
OSTI Identifier:
1570626
Alternate Identifier(s):
OSTI ID: 1562973
Report Number(s):
LA-UR-19-23908
Journal ID: ISSN 0022-1899
Grant/Contract Number:  
89233218CNA000001; 20190615PRD1
Resource Type:
Accepted Manuscript
Journal Name:
Journal of Infectious Diseases
Additional Journal Information:
Journal Name: Journal of Infectious Diseases; Journal ID: ISSN 0022-1899
Publisher:
Infectious Diseases Society of America
Country of Publication:
United States
Language:
English
Subject:
genomics; epidemiology; enterics; diarrheal diseases

Citation Formats

Domman, Daryl, Ruis, Christopher, Dorman, Matthew J., Shakya, Migun, and Chain, Patrick Sam Guy. Novel Insights Into the Spread of Enteric Pathogens Using Genomics. United States: N. p., 2019. Web. doi:10.1093/infdis/jiz220.
Domman, Daryl, Ruis, Christopher, Dorman, Matthew J., Shakya, Migun, & Chain, Patrick Sam Guy. Novel Insights Into the Spread of Enteric Pathogens Using Genomics. United States. doi:10.1093/infdis/jiz220.
Domman, Daryl, Ruis, Christopher, Dorman, Matthew J., Shakya, Migun, and Chain, Patrick Sam Guy. Fri . "Novel Insights Into the Spread of Enteric Pathogens Using Genomics". United States. doi:10.1093/infdis/jiz220.
@article{osti_1570626,
title = {Novel Insights Into the Spread of Enteric Pathogens Using Genomics},
author = {Domman, Daryl and Ruis, Christopher and Dorman, Matthew J. and Shakya, Migun and Chain, Patrick Sam Guy},
abstractNote = {Diarrheal diseases continue to be a leading cause of mortality and morbidity across the globe. The use of next-generation sequencing data has provided major insights into understanding epidemiological spread, antimicrobial resistance, vaccine effects, and basic mechanisms of bacterial and viral evolution. Furthermore, we discuss how genomic data have informed investigations across enteric pathogens, such as Shigella, Vibrio cholerae, Salmonella Typhi, rotavirus, and norovirus.},
doi = {10.1093/infdis/jiz220},
journal = {Journal of Infectious Diseases},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {9}
}

Journal Article:
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