Search Menu
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information
Search Scholarly Publications

Title: Antimicrobial resistance of enteric pathogens in the Military Health System, 2009 – 2019

Abstract

Abstract Background Acute diarrhea (AD) can have significant impacts on military troop readiness. Medical providers must understand current trends of enteropathogen antimicrobial resistance (AMR) in service members (SMs) to inform proper, timely treatment options. However, little is known of enteric pathogen profiles across the Military Health System (MHS). The primary objectives of this study were to identify gaps in enteric pathogen surveillance within the MHS, describe the epidemiology of AMR in enteric pathogens, and identify trends across the MHS both within the Continental United States (CONUS) and outside of the Continental United States (OCONUS). Methods Health Level 7 (HL7)-formatted laboratory data were queried for all specimens where Salmonella , Shigella , and Campylobacter species, as well as Shiga toxin-producing Escherichia coli ( E. coli ) (STEC) were isolated and certified between 1 January 2009 - 31 December 2019. Antibiotic susceptibility testing (AST) results were queried and summarized where available. Descriptive statistics were calculated for each organism by specimen source, year, and susceptibility testing availability. Results Among a total of 13,852 enteric bacterial isolates, 11,877 (86%) were submitted from CONUS locations. Out of 1479 Shigella spp. and 6755 Salmonella spp. isolates, 1221 (83%) and 5019 (74%), respectively, reported any susceptibility resultsmore » through the MHS. Overall, only 15% of STEC and 4% of Campylobacter spp. specimens had AST results available. Comparing AST reporting at CONUS versus OCONUS locations, AST was reported for 1175 (83%) and 46 (78%) of Shigella isolates at CONUS and OCONUS locations, respectively, and for 4591 (76%) and 428 (63%) of Salmonella isolates at CONUS and OCONUS locations, respectively. Conclusions This study revealed inconsistent enteropathogen AST conducted across the MHS, with differing trends between CONUS and OCONUS locations. Additional work is needed to assess pathogen-specific gaps in testing and reporting to develop optimal surveillance that supports the health of the force.« less

Authors:
; ; ; ; ; ; ; ; ; ;
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1902512
Resource Type:
Published Article
Journal Name:
BMC Public Health (Online)
Additional Journal Information:
Journal Name: BMC Public Health (Online) Journal Volume: 22 Journal Issue: 1; Journal ID: ISSN 1471-2458
Publisher:
Springer Science + Business Media
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Ashbaugh, Hayley, Pomeroy, Connor D., Baishya, Mona, Creppage, Kathleen, Bazaco, Sara, Johnson, Myles, Matsumoto, Kenji, Bhattarai, Upendra, Seliga, Nicholas, Graf, Paul, and Chukwuma, Uzo. Antimicrobial resistance of enteric pathogens in the Military Health System, 2009 – 2019. United Kingdom: N. p., 2022. Web. doi:10.1186/s12889-022-14466-1.
Copy to clipboard
Ashbaugh, Hayley, Pomeroy, Connor D., Baishya, Mona, Creppage, Kathleen, Bazaco, Sara, Johnson, Myles, Matsumoto, Kenji, Bhattarai, Upendra, Seliga, Nicholas, Graf, Paul, & Chukwuma, Uzo. Antimicrobial resistance of enteric pathogens in the Military Health System, 2009 – 2019. United Kingdom. https://doi.org/10.1186/s12889-022-14466-1
Copy to clipboard
Ashbaugh, Hayley, Pomeroy, Connor D., Baishya, Mona, Creppage, Kathleen, Bazaco, Sara, Johnson, Myles, Matsumoto, Kenji, Bhattarai, Upendra, Seliga, Nicholas, Graf, Paul, and Chukwuma, Uzo. Thu . "Antimicrobial resistance of enteric pathogens in the Military Health System, 2009 – 2019". United Kingdom. https://doi.org/10.1186/s12889-022-14466-1.
Copy to clipboard
@article{osti_1902512,
title = {Antimicrobial resistance of enteric pathogens in the Military Health System, 2009 – 2019},
author = {Ashbaugh, Hayley and Pomeroy, Connor D. and Baishya, Mona and Creppage, Kathleen and Bazaco, Sara and Johnson, Myles and Matsumoto, Kenji and Bhattarai, Upendra and Seliga, Nicholas and Graf, Paul and Chukwuma, Uzo},
abstractNote = {Abstract Background Acute diarrhea (AD) can have significant impacts on military troop readiness. Medical providers must understand current trends of enteropathogen antimicrobial resistance (AMR) in service members (SMs) to inform proper, timely treatment options. However, little is known of enteric pathogen profiles across the Military Health System (MHS). The primary objectives of this study were to identify gaps in enteric pathogen surveillance within the MHS, describe the epidemiology of AMR in enteric pathogens, and identify trends across the MHS both within the Continental United States (CONUS) and outside of the Continental United States (OCONUS). Methods Health Level 7 (HL7)-formatted laboratory data were queried for all specimens where Salmonella , Shigella , and Campylobacter species, as well as Shiga toxin-producing Escherichia coli ( E. coli ) (STEC) were isolated and certified between 1 January 2009 - 31 December 2019. Antibiotic susceptibility testing (AST) results were queried and summarized where available. Descriptive statistics were calculated for each organism by specimen source, year, and susceptibility testing availability. Results Among a total of 13,852 enteric bacterial isolates, 11,877 (86%) were submitted from CONUS locations. Out of 1479 Shigella spp. and 6755 Salmonella spp. isolates, 1221 (83%) and 5019 (74%), respectively, reported any susceptibility results through the MHS. Overall, only 15% of STEC and 4% of Campylobacter spp. specimens had AST results available. Comparing AST reporting at CONUS versus OCONUS locations, AST was reported for 1175 (83%) and 46 (78%) of Shigella isolates at CONUS and OCONUS locations, respectively, and for 4591 (76%) and 428 (63%) of Salmonella isolates at CONUS and OCONUS locations, respectively. Conclusions This study revealed inconsistent enteropathogen AST conducted across the MHS, with differing trends between CONUS and OCONUS locations. Additional work is needed to assess pathogen-specific gaps in testing and reporting to develop optimal surveillance that supports the health of the force.},
doi = {10.1186/s12889-022-14466-1},
journal = {BMC Public Health (Online)},
number = 1,
volume = 22,
place = {United Kingdom},
year = {Thu Dec 08 00:00:00 EST 2022},
month = {Thu Dec 08 00:00:00 EST 2022}
}
Copy to clipboard
Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
https://doi.org/10.1186/s12889-022-14466-1
Copyright Statement
Other availability
Search WorldCat Search WorldCat to find libraries that may hold this journal
Save / Share:
Export Metadata
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.

Works referenced in this record:

Trends in Antibiotic Resistance Among Diarrheal Pathogens Isolated in Thailand Over 15 Years
journal, February 1998

  • Hoge, Charles W.; Gambel, Jeffrey M.; Srijan, Apichai
  • Clinical Infectious Diseases, Vol. 26, Issue 2
  • DOI: 10.1086/516303

Volume Resuscitation and Progression to Organ Failure in Shiga Toxin-Producing Escherichia coli Infection in Adults
journal, May 2021

Diarrhoea during military deployment
journal, October 2012

  • Connor, Patrick; Porter, Chad K.; Swierczewski, Brett
  • Current Opinion in Infectious Diseases, Vol. 25, Issue 5
  • DOI: 10.1097/QCO.0b013e3283582ebc

Gastrointestinal Infections in Deployed Forces in the Middle East Theater: An Historical 60 Year Perspective
journal, November 2015

  • Riddle, Mark S.; Savarino, Stephen J.; Sanders, John W.
  • The American Journal of Tropical Medicine and Hygiene, Vol. 93, Issue 5
  • DOI: 10.4269/ajtmh.15-0200

Analysis and Presentation of Cumulative Antibiograms: A New Consensus Guideline from the Clinical and Laboratory Standards Institute
journal, March 2007

  • Hindler, J. F.; Stelling, J.
  • Clinical Infectious Diseases, Vol. 44, Issue 6
  • DOI: 10.1086/511864

Resistant pathogens as causes of traveller’s diarrhea globally and impact(s) on treatment failure and recommendations
journal, April 2017

  • Tribble, David R.
  • Journal of Travel Medicine, Vol. 24, Issue suppl_1
  • DOI: 10.1093/jtm/taw090

2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea
journal, November 2017

  • Shane, Andi L.; Mody, Rajal K.; Crump, John A.
  • Clinical Infectious Diseases, Vol. 65, Issue 12
  • DOI: 10.1093/cid/cix959

The Food Production Environment and the Development of Antimicrobial Resistance in Human Pathogens of Animal Origin
journal, March 2017

Campylobacterantimicrobial resistance in Peru: a ten-year observational study
journal, August 2012

The threat of antimicrobial resistance in developing countries: causes and control strategies
journal, May 2017

  • Ayukekbong, James A.; Ntemgwa, Michel; Atabe, Andrew N.
  • Antimicrobial Resistance & Infection Control, Vol. 6, Issue 1
  • DOI: 10.1186/s13756-017-0208-x

Foreign Travel and Decreased Ciprofloxacin Susceptibility inSalmonella entericaInfections
journal, January 2011

  • Al-Mashhadani, Manar; Hewson, Robert; Vivancos, Roberto
  • Emerging Infectious Diseases, Vol. 17, Issue 1
  • DOI: 10.3201/eid1701.100999

Epidemiology of Staphylococcus aureus Blood and Skin and Soft Tissue Infections in the US Military Health System, 2005-2010
journal, July 2012

Outcomes of diarrhea management in operations Iraqi Freedom and Enduring Freedom
journal, November 2009

  • Brown, Jamey A.; Riddle, Mark S.; Putnam, Shannon D.
  • Travel Medicine and Infectious Disease, Vol. 7, Issue 6
  • DOI: 10.1016/j.tmaid.2009.09.001

Antibiotic Therapy for Acute Watery Diarrhea and Dysentery
journal, September 2017

Shiga Toxin–ProducingEscherichia coliInfection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-analysis
journal, February 2016

  • Freedman, Stephen B.; Xie, Jianling; Neufeld, Madisen S.
  • Clinical Infectious Diseases, Vol. 62, Issue 10
  • DOI: 10.1093/cid/ciw099

A population-based estimate of the substantial burden of diarrhoeal disease in the United States; FoodNet, 1996–2003
journal, August 2006

An observational clinic-based study of diarrheal illness in deployed United States military personnel in Thailand: presentation and outcome of Campylobacter infection.
journal, November 2002

  • Sanders, J. W.; Oyofo, B. A.; Echeverria, P.
  • The American Journal of Tropical Medicine and Hygiene, Vol. 67, Issue 5
  • DOI: 10.4269/ajtmh.2002.67.533

Travelers' Diarrhea: An Update on the Incidence, Etiology, and Risk in Military Deployments and Similar Travel Populations
journal, September 2017

Incidence, Etiology, and Impact of Diarrhea Among Long-Term Travelers (us Military and Similar Populations): a Systematic Review
journal, May 2006

  • Riddle, Mark S.; Putnam, Shannon D.; Tribble, David R.
  • The American Journal of Tropical Medicine and Hygiene, Vol. 74, Issue 5
  • DOI: 10.4269/ajtmh.2006.74.891
    Sort by:
    [ × clear filter / sort ]

    Similar Records in DOE PAGES and OSTI.GOV collections: