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Title: Crassulacean Acid Metabolism Abiotic Stress-Responsive Transcription Factors: a Potential Genetic Engineering Approach for Improving Crop Tolerance to Abiotic Stress

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Publication Date:
Research Org.:
Univ. of Nevada, Reno, NV (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
Alternate Identifier(s):
OSTI ID: 1611162
Grant/Contract Number:  
Resource Type:
Published Article
Journal Name:
Frontiers in Plant Science
Additional Journal Information:
Journal Name: Frontiers in Plant Science Journal Volume: 10; Journal ID: ISSN 1664-462X
Frontiers Research Foundation
Country of Publication:
54 ENVIRONMENTAL SCIENCES; Plant Sciences; abiotic stress response; crassulacean acid metabolism; drought tolerance; extremophytes; genetic engineering; transcription factor

Citation Formats

Amin, Atia B., Rathnayake, Kumudu N., Yim, Won C., Garcia, Travis M., Wone, Beate, Cushman, John C., and Wone, Bernard W. M. Crassulacean Acid Metabolism Abiotic Stress-Responsive Transcription Factors: a Potential Genetic Engineering Approach for Improving Crop Tolerance to Abiotic Stress. Switzerland: N. p., 2019. Web. doi:10.3389/fpls.2019.00129.
Amin, Atia B., Rathnayake, Kumudu N., Yim, Won C., Garcia, Travis M., Wone, Beate, Cushman, John C., & Wone, Bernard W. M. Crassulacean Acid Metabolism Abiotic Stress-Responsive Transcription Factors: a Potential Genetic Engineering Approach for Improving Crop Tolerance to Abiotic Stress. Switzerland. doi:10.3389/fpls.2019.00129.
Amin, Atia B., Rathnayake, Kumudu N., Yim, Won C., Garcia, Travis M., Wone, Beate, Cushman, John C., and Wone, Bernard W. M. Fri . "Crassulacean Acid Metabolism Abiotic Stress-Responsive Transcription Factors: a Potential Genetic Engineering Approach for Improving Crop Tolerance to Abiotic Stress". Switzerland. doi:10.3389/fpls.2019.00129.
title = {Crassulacean Acid Metabolism Abiotic Stress-Responsive Transcription Factors: a Potential Genetic Engineering Approach for Improving Crop Tolerance to Abiotic Stress},
author = {Amin, Atia B. and Rathnayake, Kumudu N. and Yim, Won C. and Garcia, Travis M. and Wone, Beate and Cushman, John C. and Wone, Bernard W. M.},
abstractNote = {},
doi = {10.3389/fpls.2019.00129},
journal = {Frontiers in Plant Science},
number = ,
volume = 10,
place = {Switzerland},
year = {2019},
month = {2}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.3389/fpls.2019.00129

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Cited by: 4 works
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Works referenced in this record:

The Potential of Transcription Factor-Based Genetic Engineering in Improving Crop Tolerance to Drought
journal, October 2014

  • Rabara, Roel C.; Tripathi, Prateek; Rushton, Paul J.
  • OMICS: A Journal of Integrative Biology, Vol. 18, Issue 10
  • DOI: 10.1089/omi.2013.0177

Analysis of expression and evolutionary relationships of phosphoenol-pyruvate carboxylase genes in Flaveria trinervia (C4) and F. pringlei (C3)
journal, December 1990

  • Hermans, J�rgen; Westhoff, Peter
  • MGG Molecular & General Genetics, Vol. 224, Issue 3
  • DOI: 10.1007/BF00262441

Perspectives on the basic and applied aspects of crassulacean acid metabolism (CAM) research
journal, September 2018

Abscisic acid signaling and protein synthesis requirements for phosphoenolpyruvate carboxylase transcript induction in the common ice plant
journal, January 2002

Overexpression of a maize WRKY58 gene enhances drought and salt tolerance in transgenic rice
journal, July 2014

  • Cai, Ronghao; Zhao, Yang; Wang, Yufu
  • Plant Cell, Tissue and Organ Culture (PCTOC), Vol. 119, Issue 3
  • DOI: 10.1007/s11240-014-0556-7

Exploiting the potential of plants with crassulacean acid metabolism for bioenergy production on marginal lands
journal, April 2009

  • Borland, A. M.; Griffiths, H.; Hartwell, J.
  • Journal of Experimental Botany, Vol. 60, Issue 10
  • DOI: 10.1093/jxb/erp118

Induction of Crassulacean acid metabolism by water limitation
journal, February 2002

Crassulacean acid metabolism biology
journal, November 2014

  • Garcia, Travis M.; Heyduk, Karolina; Kuzmick, Emily
  • New Phytologist, Vol. 204, Issue 4
  • DOI: 10.1111/nph.13127

Transcript, protein and metabolite temporal dynamics in the CAM plant Agave
journal, November 2016

Soybean GmMYB76, GmMYB92, and GmMYB177 genes confer stress tolerance in transgenic Arabidopsis plants
journal, August 2008

  • Liao, Yong; Zou, Hong-Feng; Wang, Hui-Wen
  • Cell Research, Vol. 18, Issue 10
  • DOI: 10.1038/cr.2008.280

Transcription Factors and Plants Response to Drought Stress: Current Understanding and Future Directions
journal, July 2016

Implications of leaf ontogeny on drought-induced gradients of CAM expression and ABA levels in rosettes of the epiphytic tank bromeliad Guzmania monostachia
journal, November 2016

  • Rodrigues, Maria Aurineide; Hamachi, Leonardo; Mioto, Paulo Tamaso
  • Plant Physiology and Biochemistry, Vol. 108
  • DOI: 10.1016/j.plaphy.2016.08.010

Embracing new-generation ‘omics’ tools to improve drought tolerance in cereal and food-legume crops
journal, April 2015

Diel rewiring and positive selection of ancient plant proteins enabled evolution of CAM photosynthesis in Agave
journal, August 2018

Engineering Cold Stress Tolerance in Crop Plants
journal, March 2011

Stress Tolerance and Glucose Insensitive Phenotypes in Arabidopsis Overexpressing the CpMYB10 Transcription Factor Gene
journal, April 2004

  • Villalobos, Miguel Angel; Bartels, Dorothea; Iturriaga, Gabriel
  • Plant Physiology, Vol. 135, Issue 1
  • DOI: 10.1104/pp.103.034199

The multifaceted roles of NUCLEAR FACTOR-Y in Arabidopsis thaliana development and stress responses
journal, May 2017

  • Swain, Swadhin; Myers, Zachary A.; Siriwardana, Chamindika L.
  • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol. 1860, Issue 5
  • DOI: 10.1016/j.bbagrm.2016.10.012

The NAC Family Transcription Factor OsNAP Confers Abiotic Stress Response Through the ABA Pathway
journal, February 2014

  • Chen, Xu; Wang, Yaofeng; Lv, Bo
  • Plant and Cell Physiology, Vol. 55, Issue 3
  • DOI: 10.1093/pcp/pct204

TaNAC2, a NAC-type wheat transcription factor conferring enhanced multiple abiotic stress tolerances in Arabidopsis
journal, February 2012

  • Mao, Xinguo; Zhang, Hongying; Qian, Xueya
  • Journal of Experimental Botany, Vol. 63, Issue 8
  • DOI: 10.1093/jxb/err462

Over-expression of the stress-induced OsWRKY45 enhances disease resistance and drought tolerance in Arabidopsis
journal, January 2009

Reversible Burst of Transcriptional Changes during Induction of Crassulacean Acid Metabolism in Talinum triangulare
journal, November 2015

  • Brilhaus, Dominik; Bräutigam, Andrea; Mettler-Altmann, Tabea
  • Plant Physiology, Vol. 170, Issue 1
  • DOI: 10.1104/pp.15.01076

Global warming and 21st century drying
journal, March 2014

Crop Production under Drought and Heat Stress: Plant Responses and Management Options
journal, June 2017

The pineapple genome and the evolution of CAM photosynthesis
journal, November 2015

  • Ming, Ray; VanBuren, Robert; Wai, Ching Man
  • Nature Genetics, Vol. 47, Issue 12
  • DOI: 10.1038/ng.3435

Engineering drought tolerance in plants: discovering and tailoring genes to unlock the future
journal, April 2006

Engineering crassulacean acid metabolism to improve water-use efficiency
journal, May 2014

Crassulacean acid metabolism under global climate change: Meetings
journal, February 2009

Temporal and spatial transcriptomic and micro RNA dynamics of CAM photosynthesis in pineapple
journal, August 2017

  • Wai, Ching M.; VanBuren, Robert; Zhang, Jisen
  • The Plant Journal, Vol. 92, Issue 1
  • DOI: 10.1111/tpj.13630

Recent Advances in Utilizing Transcription Factors to Improve Plant Abiotic Stress Tolerance by Transgenic Technology
journal, February 2016

Climate-resilient agroforestry: physiological responses to climate change and engineering of crassulacean acid metabolism (CAM) as a mitigation strategy: CAM engineering in trees
journal, December 2014

  • Borland, Anne M.; Wullschleger, Stan D.; Weston, David J.
  • Plant, Cell & Environment, Vol. 38, Issue 9
  • DOI: 10.1111/pce.12479

A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world
journal, July 2015

  • Yang, Xiaohan; Cushman, John C.; Borland, Anne M.
  • New Phytologist, Vol. 207, Issue 3
  • DOI: 10.1111/nph.13393

Global Synthesis of Drought Effects on Maize and Wheat Production
journal, May 2016

Facultative crassulacean acid metabolism (CAM) plants: powerful tools for unravelling the functional elements of CAM photosynthesis
journal, March 2014

  • Winter, K.; Holtum, J. A. M.
  • Journal of Experimental Botany, Vol. 65, Issue 13
  • DOI: 10.1093/jxb/eru063

Functional and Transcriptome Analysis Reveals an Acclimatization Strategy for Abiotic Stress Tolerance Mediated by Arabidopsis NF-YA Family Members
journal, October 2012

  • Leyva-González, Marco Antonio; Ibarra-Laclette, Enrique; Cruz-Ramírez, Alfredo
  • PLoS ONE, Vol. 7, Issue 10
  • DOI: 10.1371/journal.pone.0048138

Plant NF-Y transcription factors: Key players in plant-microbe interactions, root development and adaptation to stress
journal, May 2017

  • Zanetti, María Eugenia; Rípodas, Carolina; Niebel, Andreas
  • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol. 1860, Issue 5
  • DOI: 10.1016/j.bbagrm.2016.11.007

Isolation and Characterization of Mutants of Common Ice Plant Deficient in Crassulacean Acid Metabolism
journal, March 2008

  • Cushman, John C.; Agarie, Sakae; Albion, Rebecca L.
  • Plant Physiology, Vol. 147, Issue 1
  • DOI: 10.1104/pp.108.116889

Transcription factors as tools to engineer enhanced drought stress tolerance in plants
journal, February 2011

  • Hussain, Syed Sarfraz; Kayani, Mahmood Akhtar; Amjad, Muhammad
  • Biotechnology Progress, Vol. 27, Issue 2
  • DOI: 10.1002/btpr.514

Crassulacean Acid Metabolism. A Plastic Photosynthetic Adaptation to Arid Environments
journal, December 2001

A R2R3-type MYB gene, OsMYB2, is involved in salt, cold, and dehydration tolerance in rice
journal, February 2012

  • Yang, An; Dai, Xiaoyan; Zhang, Wen-Hao
  • Journal of Experimental Botany, Vol. 63, Issue 7
  • DOI: 10.1093/jxb/err431

Induction of Crassulacean Acid Metabolism in the Facultative Halophyte Mesembryanthemum crystallinum by Abscisic Acid
journal, July 1990

  • Chu, Chun; Dai, Ziyu; Ku, Maurice S. B.
  • Plant Physiology, Vol. 93, Issue 3
  • DOI: 10.1104/pp.93.3.1253

Pineapple Genome: A Reference for Monocots and CAM Photosynthesis
journal, November 2016

Emerging model systems for functional genomics analysis of Crassulacean acid metabolism
journal, June 2016

  • Hartwell, James; Dever, Louisa V.; Boxall, Susanna F.
  • Current Opinion in Plant Biology, Vol. 31
  • DOI: 10.1016/j.pbi.2016.03.019

NAC transcription factors in plant abiotic stress responses
journal, February 2012

  • Nakashima, Kazuo; Takasaki, Hironori; Mizoi, Junya
  • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol. 1819, Issue 2
  • DOI: 10.1016/j.bbagrm.2011.10.005

Shifts in gene expression profiles are associated with weak and strong Crassulacean acid metabolism
journal, February 2018

  • Heyduk, Karolina; Ray, Jeremy N.; Ayyampalayam, Saravanaraj
  • American Journal of Botany, Vol. 105, Issue 3
  • DOI: 10.1002/ajb2.1017

Climate Trends and Global Crop Production Since 1980
journal, May 2011

Potential utilization of NAC transcription factors to enhance abiotic stress tolerance in plants by biotechnological approach
journal, January 2010

  • Tran, Lam-Son Phan; Nishiyama, Rie; Yamaguchi-Shinozaki, Kazuko
  • GM Crops, Vol. 1, Issue 1
  • DOI: 10.4161/gmcr.1.1.10569

Evolution along the crassulacean acid metabolism continuum
journal, January 2010

  • Silvera, Katia; Neubig, Kurt M.; Whitten, W. Mark
  • Functional Plant Biology, Vol. 37, Issue 11
  • DOI: 10.1071/FP10084

Systems biology: A new CAM era
journal, November 2016

Soil salinity: A serious environmental issue and plant growth promoting bacteria as one of the tools for its alleviation
journal, March 2015

Development and use of bioenergy feedstocks for semi-arid and arid lands
journal, April 2015

  • Cushman, John C.; Davis, Sarah C.; Yang, Xiaohan
  • Journal of Experimental Botany, Vol. 66, Issue 14
  • DOI: 10.1093/jxb/erv087

A Vitis vinifera basic helix-loop-helix transcription factor enhances plant cell size, vegetative biomass and reproductive yield
journal, April 2018

  • Lim, Sung Don; Yim, Won Choel; Liu, Degao
  • Plant Biotechnology Journal, Vol. 16, Issue 9
  • DOI: 10.1111/pbi.12898

Plant Life in Extreme Environments: How Do You Improve Drought Tolerance?
journal, May 2018

Temperature extremes: Effect on plant growth and development
journal, December 2015

Transcriptome Comparison Reveals Distinct Selection Patterns in Domesticated and Wild Agave Species, the Important CAM Plants
journal, November 2018

  • Huang, Xing; Wang, Bo; Xi, Jingen
  • International Journal of Genomics, Vol. 2018
  • DOI: 10.1155/2018/5716518

Transcriptional Regulatory Networks in Cellular Responses and Tolerance to Dehydration and cold Stresses
journal, June 2006

Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances drought resistance and salt tolerance in rice
journal, August 2006

  • Hu, H.; Dai, M.; Yao, J.
  • Proceedings of the National Academy of Sciences, Vol. 103, Issue 35
  • DOI: 10.1073/pnas.0604882103

Sorghum phosphoenolpyruvate carboxylase gene family: structure, function and molecular evolution
journal, February 1993

  • Lepiniec, Lo�c; Keryer, Eliane; Philippe, Herve
  • Plant Molecular Biology, Vol. 21, Issue 3
  • DOI: 10.1007/BF00028806

The Kalanchoë genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism
journal, December 2017

A meta-analysis of crop yield under climate change and adaptation
journal, March 2014

  • Challinor, A. J.; Watson, J.; Lobell, D. B.
  • Nature Climate Change, Vol. 4, Issue 4
  • DOI: 10.1038/nclimate2153

World population stabilization unlikely this century
journal, September 2014

Influence of extreme weather disasters on global crop production
journal, January 2016

  • Lesk, Corey; Rowhani, Pedram; Ramankutty, Navin
  • Nature, Vol. 529, Issue 7584
  • DOI: 10.1038/nature16467

Overexpression of a NAC transcription factor enhances rice drought and salt tolerance
journal, February 2009

  • Zheng, Xingnan; Chen, Bo; Lu, Guojun
  • Biochemical and Biophysical Research Communications, Vol. 379, Issue 4
  • DOI: 10.1016/j.bbrc.2008.12.163

Food Security: The Challenge of Feeding 9 Billion People
journal, January 2010

A transcription factor hierarchy defines an environmental stress response network
journal, November 2016

Signaling Events Leading to Crassulacean Acid Metabolism Induction in the Common Ice Plant
journal, October 1999