Microscopic diffusion processes measured in living planarians
Abstract
Living planarian flatworms were probed using quasielastic neutron scattering to measure, on the pico-to-nanosecond time scale and nanometer length scale, microscopic diffusion of water and cell constituents in the planarians. Measurable microscopic diffusivities were surprisingly well defined in such a complex system as living animals. The overall variation in the microscopic diffusivity of cell constituents was found to be far lower than the variation in the microscopic diffusivity of water in planarians in a temperature range of 284.5 to 304.1K.
- Authors:
-
[1]
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Neutron Scattering Division
- Publication Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1426585
- Grant/Contract Number:
- AC05-00OR22725
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Scientific Reports
- Additional Journal Information:
- Journal Volume: 8; Journal Issue: 1; Journal ID: ISSN 2045-2322
- Publisher:
- Nature Publishing Group
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 77 NANOSCIENCE AND NANOTECHNOLOGY
Citation Formats
Mamontov, Eugene. Microscopic diffusion processes measured in living planarians. United States: N. p., 2018.
Web. doi:10.1038/s41598-018-22643-9.
Mamontov, Eugene. Microscopic diffusion processes measured in living planarians. United States. https://doi.org/10.1038/s41598-018-22643-9
Mamontov, Eugene. Thu .
"Microscopic diffusion processes measured in living planarians". United States. https://doi.org/10.1038/s41598-018-22643-9. https://www.osti.gov/servlets/purl/1426585.
@article{osti_1426585,
title = {Microscopic diffusion processes measured in living planarians},
author = {Mamontov, Eugene},
abstractNote = {Living planarian flatworms were probed using quasielastic neutron scattering to measure, on the pico-to-nanosecond time scale and nanometer length scale, microscopic diffusion of water and cell constituents in the planarians. Measurable microscopic diffusivities were surprisingly well defined in such a complex system as living animals. The overall variation in the microscopic diffusivity of cell constituents was found to be far lower than the variation in the microscopic diffusivity of water in planarians in a temperature range of 284.5 to 304.1K.},
doi = {10.1038/s41598-018-22643-9},
journal = {Scientific Reports},
number = 1,
volume = 8,
place = {United States},
year = {Thu Mar 08 00:00:00 EST 2018},
month = {Thu Mar 08 00:00:00 EST 2018}
}
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Works referenced in this record:
Evolution of the Internal Dynamics of Two Globular Proteins from Dry Powder to Solution
journal, July 1999
- Pérez, Javier; Zanotti, Jean-Marc; Durand, Dominique
- Biophysical Journal, Vol. 77, Issue 1
Water Dynamics in Neural Tissue
journal, January 2013
- Natali, Francesca; Dolce, Caterina; Peters, Judith
- Journal of the Physical Society of Japan, Vol. 82, Issue Suppl.A
Salt-Induced Universal Slowing Down of the Short-Time Self-Diffusion of a Globular Protein in Aqueous Solution
journal, June 2015
- Grimaldo, Marco; Roosen-Runge, Felix; Hennig, Marcus
- The Journal of Physical Chemistry Letters, Vol. 6, Issue 13
Down to atomic-scale intracellular water dynamics
journal, May 2008
- Jasnin, Marion; Moulin, Martina; Haertlein, Michael
- The EMBO Journal, Vol. 9, Issue 6
Protein self-diffusion in crowded solutions
journal, July 2011
- Roosen-Runge, F.; Hennig, M.; Zhang, F.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 29
Dynamical and Phase Behavior of a Phospholipid Membrane Altered by an Antimicrobial Peptide at Low Concentration
journal, June 2016
- Sharma, V. K.; Mamontov, E.; Tyagi, M.
- The Journal of Physical Chemistry Letters, Vol. 7, Issue 13
Diffusion and Dynamics of γ-Globulin in Crowded Aqueous Solutions
journal, June 2014
- Grimaldo, Marco; Roosen-Runge, Felix; Zhang, Fajun
- The Journal of Physical Chemistry B, Vol. 118, Issue 25
In Vivo Measurement of Internal and Global Macromolecular Motions in Escherichia coli
journal, July 2008
- Jasnin, M.; Moulin, M.; Haertlein, M.
- Biophysical Journal, Vol. 95, Issue 2
Microscopic diffusion in hydrated encysted eggs of brine shrimp
journal, September 2017
- Mamontov, E.
- Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1861, Issue 9
Effect of α-Tocopherol on the Microscopic Dynamics of Dimyristoylphosphatidylcholine Membrane
journal, December 2015
- Sharma, V. K.; Mamontov, E.; Tyagi, M.
- The Journal of Physical Chemistry B, Vol. 120, Issue 1
Water–protein dynamic coupling and new opportunities for probing it at low to physiological temperatures in aqueous solutions
journal, January 2012
- Mamontov, Eugene; Chu, Xiang-qiang
- Physical Chemistry Chemical Physics, Vol. 14, Issue 33
Anomalous proton dynamics of water molecules in neural tissue as seen by quasi-elastic neutron scattering. Impact on medical imaging techniques
conference, January 2013
- Natali, F.; Gerelli, Y.; Stelletta, C.
- 4TH INTERNATIONAL SYMPOSIUM ON SLOW DYNAMICS IN COMPLEX SYSTEMS: Keep Going Tohoku, AIP Conference Proceedings
Nanoscopic Dynamics of Phospholipid in Unilamellar Vesicles: Effect of Gel to Fluid Phase Transition
journal, March 2015
- Sharma, V. K.; Mamontov, E.; Anunciado, D. B.
- The Journal of Physical Chemistry B, Vol. 119, Issue 12
Quasi-elastic neutron scattering in the multi-GPa range and its application to liquid water
journal, November 2013
- Klotz, S.; Strässle, Th.; Bove, L. E.
- Applied Physics Letters, Vol. 103, Issue 19
Revealing the Dynamics of Thylakoid Membranes in Living Cyanobacterial Cells
journal, January 2016
- Stingaciu, Laura-Roxana; O’Neill, Hugh; Liberton, Michelle
- Scientific Reports, Vol. 6, Issue 1
Dynamics of well-folded and natively disordered proteins in solution: a time-of-flight neutron scattering study
journal, January 2008
- Gaspar, A. M.; Appavou, M. -S.; Busch, S.
- European Biophysics Journal, Vol. 37, Issue 5
Fast internal dynamics in alcohol dehydrogenase
journal, August 2015
- Monkenbusch, M.; Stadler, A.; Biehl, R.
- The Journal of Chemical Physics, Vol. 143, Issue 7
Hemoglobin Dynamics in Red Blood Cells: Correlation to Body Temperature
journal, December 2008
- Stadler, A. M.; Digel, I.; Artmann, G. M.
- Biophysical Journal, Vol. 95, Issue 11
Deep Sea Microbes Probed by Incoherent Neutron Scattering Under High Hydrostatic Pressure
journal, January 2014
- Peters, Judith; Martinez, Nicolas; Michoud, Grégoire
- Zeitschrift für Physikalische Chemie, Vol. 228, Issue 10-12
In Vivo Protein Dynamics on the Nanometer Length Scale and Nanosecond Time Scale
journal, April 2017
- Anunciado, Divina B.; Nyugen, Vyncent P.; Hurst, Gregory B.
- The Journal of Physical Chemistry Letters, Vol. 8, Issue 8
Low-density lipoproteins investigated under high hydrostatic pressure by elastic incoherent neutron scattering
journal, July 2017
- Peters, J.; Martinez, N.; Lehofer, B.
- The European Physical Journal E, Vol. 40, Issue 7
Specific cellular water dynamics observed in vivo by neutron scattering and NMR
journal, January 2010
- Jasnin, Marion; Stadler, Andreas; Tehei, Moeava
- Physical Chemistry Chemical Physics, Vol. 12, Issue 35
Self-diffusion in normal and heavy water in the range 1-45.deg.
journal, March 1973
- Mills, R.
- The Journal of Physical Chemistry, Vol. 77, Issue 5
Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells
journal, July 2013
- Feijó Delgado, Francisco; Cermak, Nathan; Hecht, Vivian C.
- PLoS ONE, Vol. 8, Issue 7
Lipid droplets: a unified view of a dynamic organelle
journal, March 2006
- Martin, Sally; Parton, Robert G.
- Nature Reviews Molecular Cell Biology, Vol. 7, Issue 5
Neutron scattering: a tool to detect in vivo thermal stress effects at the molecular dynamics level in micro-organisms
journal, May 2013
- Marty, Vincent; Jasnin, Marion; Fabiani, Elisa
- Journal of The Royal Society Interface, Vol. 10, Issue 82
Molecular adaptation and salt stress response of Halobacterium salinarum cells revealed by neutron spectroscopy
journal, September 2015
- Vauclare, Pierre; Marty, Vincent; Fabiani, Elisa
- Extremophiles, Vol. 19, Issue 6
Differential scanning calorimetry of porcine adipose tissues
journal, April 2006
- Sasaki, K.; Mitsumoto, M.; Nishioka, T.
- Meat Science, Vol. 72, Issue 4
High protein flexibility and reduced hydration water dynamics are key pressure adaptive strategies in prokaryotes
journal, September 2016
- Martinez, N.; Michoud, G.; Cario, A.
- Scientific Reports, Vol. 6, Issue 1
Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells
journal, December 2008
- Stadler, Andreas M.; Embs, Jan P.; Digel, Ilya
- Journal of the American Chemical Society, Vol. 130, Issue 50
A time-of-flight backscattering spectrometer at the Spallation Neutron Source, BASIS
journal, August 2011
- Mamontov, E.; Herwig, K. W.
- Review of Scientific Instruments, Vol. 82, Issue 8
Protein diffusion in crowded electrolyte solutions
journal, January 2010
- Roosen-Runge, Felix; Hennig, Marcus; Seydel, Tilo
- Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol. 1804, Issue 1
From shell to cell: neutron scattering studies of biological water dynamics and coupling to activity
journal, January 2009
- Frölich, A.; Gabel, F.; Jasnin, M.
- Faraday Discuss., Vol. 141
Intracellular water – an overlooked drug target? Cisplatin impact in cancer cells probed by neutrons
journal, January 2017
- Marques, M. P. M.; Batista de Carvalho, A. L. M.; Sakai, V. Garcia
- Physical Chemistry Chemical Physics, Vol. 19, Issue 4
Dynamics of highly concentrated protein solutions around the denaturing transition
journal, January 2012
- Hennig, Marcus; Roosen-Runge, Felix; Zhang, Fajun
- Soft Matter, Vol. 8, Issue 5
Hierarchical molecular dynamics of bovine serum albumin in concentrated aqueous solution below and above thermal denaturation
journal, January 2015
- Grimaldo, Marco; Roosen-Runge, Felix; Hennig, Marcus
- Physical Chemistry Chemical Physics, Vol. 17, Issue 6
Effect of antimicrobial peptide on the dynamics of phosphocholine membrane: role of cholesterol and physical state of bilayer
journal, January 2015
- Sharma, V. K.; Mamontov, E.; Anunciado, D. B.
- Soft Matter, Vol. 11, Issue 34
Dynamics of well-folded and natively disordered proteins in solution: a time-of-flight neutron scattering study
journal, January 2008
- Gaspar, A. M.; Appavou, M. -S.; Busch, S.
- European Biophysics Journal, Vol. 37, Issue 5
Molecular adaptation and salt stress response of Halobacterium salinarum cells revealed by neutron spectroscopy
journal, September 2015
- Vauclare, Pierre; Marty, Vincent; Fabiani, Elisa
- Extremophiles, Vol. 19, Issue 6
Microscopic diffusion in hydrated encysted eggs of brine shrimp
journal, September 2017
- Mamontov, E.
- Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1861, Issue 9
Protein diffusion in crowded electrolyte solutions
journal, January 2010
- Roosen-Runge, Felix; Hennig, Marcus; Seydel, Tilo
- Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol. 1804, Issue 1
Differential scanning calorimetry of porcine adipose tissues
journal, April 2006
- Sasaki, K.; Mitsumoto, M.; Nishioka, T.
- Meat Science, Vol. 72, Issue 4
Effect of α-Tocopherol on the Microscopic Dynamics of Dimyristoylphosphatidylcholine Membrane
journal, December 2015
- Sharma, V. K.; Mamontov, E.; Tyagi, M.
- The Journal of Physical Chemistry B, Vol. 120, Issue 1
Salt-Induced Universal Slowing Down of the Short-Time Self-Diffusion of a Globular Protein in Aqueous Solution
journal, June 2015
- Grimaldo, Marco; Roosen-Runge, Felix; Hennig, Marcus
- The Journal of Physical Chemistry Letters, Vol. 6, Issue 13
Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells
journal, December 2008
- Stadler, Andreas M.; Embs, Jan P.; Digel, Ilya
- Journal of the American Chemical Society, Vol. 130, Issue 50
Down to atomic-scale intracellular water dynamics
journal, May 2008
- Jasnin, Marion; Moulin, Martina; Haertlein, Michael
- The EMBO Journal, Vol. 9, Issue 6
Specific cellular water dynamics observed in vivo by neutron scattering and NMR
journal, January 2010
- Jasnin, Marion; Stadler, Andreas; Tehei, Moeava
- Physical Chemistry Chemical Physics, Vol. 12, Issue 35
Water–protein dynamic coupling and new opportunities for probing it at low to physiological temperatures in aqueous solutions
journal, January 2012
- Mamontov, Eugene; Chu, Xiang-qiang
- Physical Chemistry Chemical Physics, Vol. 14, Issue 33
Anomalous proton dynamics of water molecules in neural tissue as seen by quasi-elastic neutron scattering. Impact on medical imaging techniques
conference, January 2013
- Natali, F.; Gerelli, Y.; Stelletta, C.
- 4TH INTERNATIONAL SYMPOSIUM ON SLOW DYNAMICS IN COMPLEX SYSTEMS: Keep Going Tohoku, AIP Conference Proceedings
Quasi-elastic neutron scattering in the multi-GPa range and its application to liquid water
journal, November 2013
- Klotz, S.; Strässle, Th.; Bove, L. E.
- Applied Physics Letters, Vol. 103, Issue 19
Protein self-diffusion in crowded solutions
journal, July 2011
- Roosen-Runge, F.; Hennig, M.; Zhang, F.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 29
Organization and Flexibility of Cyanobacterial Thylakoid Membranes Examined by Neutron Scattering
journal, December 2012
- Liberton, Michelle; Page, Lawrence E.; O'Dell, William B.
- Journal of Biological Chemistry, Vol. 288, Issue 5
Neutron scattering: a tool to detect in vivo thermal stress effects at the molecular dynamics level in micro-organisms
journal, May 2013
- Marty, Vincent; Jasnin, Marion; Fabiani, Elisa
- Journal of The Royal Society Interface, Vol. 10, Issue 82
Multiple-scattering effects on smooth neutron-scattering spectra
journal, November 2000
- Wuttke, Joachim
- Physical Review E, Vol. 62, Issue 5
Low-density lipoproteins investigated under high hydrostatic pressure by elastic incoherent neutron scattering
journal, July 2017
- Peters, J.; Martinez, N.; Lehofer, B.
- The European Physical Journal E, Vol. 40, Issue 7
In Vivo Measurement of Internal and Global Macromolecular Motions in Escherichia coli
journal, July 2008
- Jasnin, M.; Moulin, M.; Haertlein, M.
- Biophysical Journal, Vol. 95, Issue 2
Hemoglobin Dynamics in Red Blood Cells: Correlation to Body Temperature
journal, December 2008
- Stadler, A. M.; Digel, I.; Artmann, G. M.
- Biophysical Journal, Vol. 95, Issue 11
Works referencing / citing this record:
Dynamics of proteins in solution
journal, January 2019
- Grimaldo, Marco; Roosen-Runge, Felix; Zhang, Fajun
- Quarterly Reviews of Biophysics, Vol. 52
Water dynamics in MCF-7 breast cancer cells: a neutron scattering descriptive study
journal, June 2019
- Martins, Murillo L.; Dinitzen, Alexander B.; Mamontov, Eugene
- Scientific Reports, Vol. 9, Issue 1
High-resolution neutron spectroscopy using backscattering and neutron spin-echo spectrometers in soft and hard condensed matter
journal, January 2020
- Gardner, Jason S.; Ehlers, Georg; Faraone, Antonio
- Nature Reviews Physics, Vol. 2, Issue 2
Neutron scattering in the biological sciences: progress and prospects
journal, December 2018
- Ashkar, Rana; Bilheux, Hassina Z.; Bordallo, Heliosa
- Acta Crystallographica Section D Structural Biology, Vol. 74, Issue 12
Neutron spectroscopy on protein solutions employing backscattering with an increased energy range
journal, June 2019
- Beck, Christian; Appel, Markus; Grimaldo, Marco
- Physica B: Condensed Matter, Vol. 562
Temperature dependence of nanoscale dynamic processes measured in living millipedes by high resolution inelastic and elastic neutron scattering
journal, August 2019
- Mamontov, Eugene; Osti, Naresh C.; Tyagi, Madhusudan
- Scientific Reports, Vol. 9, Issue 1