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Title: Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors

Authors:
; ; ; ; ; ; ; ; ; ;
Publication Date:
Type:
Publisher's Accepted Manuscript
Journal Name:
Bioorganic and Medicinal Chemistry Letters
Additional Journal Information:
Journal Volume: 27; Journal Issue: 12; Related Information: CHORUS Timestamp: 2018-09-02 13:22:56; Journal ID: ISSN 0960-894X
Publisher:
Elsevier
Sponsoring Org:
USDOE
Country of Publication:
United Kingdom
Language:
English
OSTI Identifier:
1416585

Huang, Wenlin, Zhang, Zhongsheng, Ranade, Ranae M., Gillespie, J. Robert, Barros-Álvarez, Ximena, Creason, Sharon A., Shibata, Sayaka, Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., and Fan, Erkang. Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors. United Kingdom: N. p., Web. doi:10.1016/j.bmcl.2017.04.048.
Huang, Wenlin, Zhang, Zhongsheng, Ranade, Ranae M., Gillespie, J. Robert, Barros-Álvarez, Ximena, Creason, Sharon A., Shibata, Sayaka, Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., & Fan, Erkang. Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors. United Kingdom. doi:10.1016/j.bmcl.2017.04.048.
Huang, Wenlin, Zhang, Zhongsheng, Ranade, Ranae M., Gillespie, J. Robert, Barros-Álvarez, Ximena, Creason, Sharon A., Shibata, Sayaka, Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., and Fan, Erkang. 2017. "Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors". United Kingdom. doi:10.1016/j.bmcl.2017.04.048.
@article{osti_1416585,
title = {Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors},
author = {Huang, Wenlin and Zhang, Zhongsheng and Ranade, Ranae M. and Gillespie, J. Robert and Barros-Álvarez, Ximena and Creason, Sharon A. and Shibata, Sayaka and Verlinde, Christophe L. M. J. and Hol, Wim G. J. and Buckner, Frederick S. and Fan, Erkang},
abstractNote = {},
doi = {10.1016/j.bmcl.2017.04.048},
journal = {Bioorganic and Medicinal Chemistry Letters},
number = 12,
volume = 27,
place = {United Kingdom},
year = {2017},
month = {6}
}