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Title: 5-Fluoroimidazo[4,5- b ]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors

Authors:
 [1] ;  [1] ;  [2] ;  [1] ;  [2] ;  [2] ;  [1] ;  [1] ;  [3] ;  [3] ;  [1] ;  [1] ;  [2] ;  [1]
  1. Department of Biochemistry, University of Washington, 1705 N.E. Pacific Street, Seattle, Washington 98195, United States
  2. Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington, 750 Republican Street, Seattle, Washington 98109, United States
  3. Department of Chemistry, Bagley Hall, University of Washington, Seattle, Washington 98195, United States
Publication Date:
Grant/Contract Number:
AC02-76SF00515
Type:
Published Article
Journal Name:
ACS Infectious Diseases
Additional Journal Information:
Journal Name: ACS Infectious Diseases Journal Volume: 2 Journal Issue: 6; Journal ID: ISSN 2373-8227
Publisher:
American Chemical Society
Sponsoring Org:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
Country of Publication:
United States
Language:
English
OSTI Identifier:
1331717

Zhang, Zhongsheng, Koh, Cho Yeow, Ranade, Ranae M., Shibata, Sayaka, Gillespie, J. Robert, Hulverson, Matthew A., Huang, Wenlin, Nguyen, Jasmine, Pendem, Nagendar, Gelb, Michael H., Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., and Fan, Erkang. 5-Fluoroimidazo[4,5- b ]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors. United States: N. p., Web. doi:10.1021/acsinfecdis.6b00036.
Zhang, Zhongsheng, Koh, Cho Yeow, Ranade, Ranae M., Shibata, Sayaka, Gillespie, J. Robert, Hulverson, Matthew A., Huang, Wenlin, Nguyen, Jasmine, Pendem, Nagendar, Gelb, Michael H., Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., & Fan, Erkang. 5-Fluoroimidazo[4,5- b ]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors. United States. doi:10.1021/acsinfecdis.6b00036.
Zhang, Zhongsheng, Koh, Cho Yeow, Ranade, Ranae M., Shibata, Sayaka, Gillespie, J. Robert, Hulverson, Matthew A., Huang, Wenlin, Nguyen, Jasmine, Pendem, Nagendar, Gelb, Michael H., Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., and Fan, Erkang. 2016. "5-Fluoroimidazo[4,5- b ]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors". United States. doi:10.1021/acsinfecdis.6b00036.
@article{osti_1331717,
title = {5-Fluoroimidazo[4,5- b ]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors},
author = {Zhang, Zhongsheng and Koh, Cho Yeow and Ranade, Ranae M. and Shibata, Sayaka and Gillespie, J. Robert and Hulverson, Matthew A. and Huang, Wenlin and Nguyen, Jasmine and Pendem, Nagendar and Gelb, Michael H. and Verlinde, Christophe L. M. J. and Hol, Wim G. J. and Buckner, Frederick S. and Fan, Erkang},
abstractNote = {},
doi = {10.1021/acsinfecdis.6b00036},
journal = {ACS Infectious Diseases},
number = 6,
volume = 2,
place = {United States},
year = {2016},
month = {4}
}