Maintaining the factory: the roles of the unfolded protein response in cellular homeostasis in plants
Abstract
Similar to a factory, the endoplasmic reticulum (ER) assembles simple cellular building blocks into complex molecular machines known as proteins. In order to protect the delicate protein folding process and ensure the proper cellular delivery of protein products under environmental stresses, eukaryotes have evolved a set of signaling mechanisms known as the unfolded protein response (UPR) to increase the folding capacity of the ER. This process is particularly important in plants, because their sessile nature commands adaptation for survival rather than escape from stress. Thus, plants make special use of the UPR, and evidence indicates that the master regulators and downstream effectors of the UPR have distinct roles in mediating cellular processes that affect organism growth and development as well as stress responses. In this review we outline recent developments in this field that support a strong relevance of the UPR to many areas of plant life.
- Authors:
-
[1];
- Michigan State Univ., East Lansing, MI (United States). MSU‐DOE Plant Research Lab. and Plant Biology Dept.
- Michigan State Univ., East Lansing, MI (United States). MSU‐DOE Plant Research Lab., Plant Biology Dept., and Great Lakes Bioenergy Research Center
- Publication Date:
- Research Org.:
- Michigan State Univ., East Lansing, MI (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences, and Biosciences Division; USDOE Office of Science (SC), Biological and Environmental Research (BER); National Institutes of Health (NIH); National Aeronautics and Space Administration (NASA)
- OSTI Identifier:
- 1596259
- Alternate Identifier(s):
- OSTI ID: 1401500
- Grant/Contract Number:
- FG02‐91ER20021; FC02‐07ER64494; NNX12AN71G; R01‐GM101038; T32‐GM110523
- Resource Type:
- Accepted Manuscript
- Journal Name:
- The Plant Journal
- Additional Journal Information:
- Journal Volume: 90; Journal Issue: 4; Journal ID: ISSN 0960-7412
- Publisher:
- Society for Experimental Biology
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; unfolded protein response; ER stress; IRE1; bZIP60; bZIP28; Arabidopsis thaliana
Citation Formats
Angelos, Evan, Ruberti, Cristina, Kim, Sang-Jin, and Brandizzi, Federica. Maintaining the factory: the roles of the unfolded protein response in cellular homeostasis in plants. United States: N. p., 2016.
Web. doi:10.1111/tpj.13449.
Angelos, Evan, Ruberti, Cristina, Kim, Sang-Jin, & Brandizzi, Federica. Maintaining the factory: the roles of the unfolded protein response in cellular homeostasis in plants. United States. https://doi.org/10.1111/tpj.13449
Angelos, Evan, Ruberti, Cristina, Kim, Sang-Jin, and Brandizzi, Federica. Sat .
"Maintaining the factory: the roles of the unfolded protein response in cellular homeostasis in plants". United States. https://doi.org/10.1111/tpj.13449. https://www.osti.gov/servlets/purl/1596259.
@article{osti_1596259,
title = {Maintaining the factory: the roles of the unfolded protein response in cellular homeostasis in plants},
author = {Angelos, Evan and Ruberti, Cristina and Kim, Sang-Jin and Brandizzi, Federica},
abstractNote = {Similar to a factory, the endoplasmic reticulum (ER) assembles simple cellular building blocks into complex molecular machines known as proteins. In order to protect the delicate protein folding process and ensure the proper cellular delivery of protein products under environmental stresses, eukaryotes have evolved a set of signaling mechanisms known as the unfolded protein response (UPR) to increase the folding capacity of the ER. This process is particularly important in plants, because their sessile nature commands adaptation for survival rather than escape from stress. Thus, plants make special use of the UPR, and evidence indicates that the master regulators and downstream effectors of the UPR have distinct roles in mediating cellular processes that affect organism growth and development as well as stress responses. In this review we outline recent developments in this field that support a strong relevance of the UPR to many areas of plant life.},
doi = {10.1111/tpj.13449},
journal = {The Plant Journal},
number = 4,
volume = 90,
place = {United States},
year = {Sat Dec 10 00:00:00 EST 2016},
month = {Sat Dec 10 00:00:00 EST 2016}
}
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