Shape control and compartmentalization in active colloidal cells
Abstract
Small autonomous machines like biological cells or soft robots can convert energy input into control of function and form. It is desired that this behavior emerges spontaneously and can be easily switched over time. For this purpose, in this paper we introduce an active matter system that is loosely inspired by biology and which we term an active colloidal cell. The active colloidal cell consists of a boundary and a fluid interior, both of which are built from identical rotating spinners whose activity creates convective flows. Similarly to biological cell motility, which is driven by cytoskeletal components spread throughout the entire volume of the cell, active colloidal cells are characterized by highly distributed energy conversion. We demonstrate that we can control the shape of the active colloidal cell and drive compartmentalization by varying the details of the boundary (hard vs. flexible) and the character of the spinners (passive vs. active). We report buckling of the boundary controlled by the pattern of boundary activity, as well as formation of core–shell and inverted Janus phase-separated configurations within the active cell interior. As the cell size is increased, the inverted Janus configuration spontaneously breaks its mirror symmetry. The result is a bubble–crescent configuration,more »
- Authors:
-
- Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109,, Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109,
- Department of Chemical Engineering, Pennsylvania State University, University Park, PA 16802,
- Department of Chemical Engineering, Pennsylvania State University, University Park, PA 16802,, Department of NanoEngineering, University of California, San Diego, La Jolla, CA 92093,
- Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109,
- Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109,, Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109,, Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI 48109
- Publication Date:
- Research Org.:
- Univ. of Michigan, Ann Arbor, MI (United States); Pennsylvania State Univ., University Park, PA (United States); Energy Frontier Research Centers (EFRC) (United States). Center for Bio-Inspired Energy Science (CBES)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1235147
- Alternate Identifier(s):
- OSTI ID: 1347961
- Grant/Contract Number:
- SC00000989; SC0000989
- Resource Type:
- Published Article
- Journal Name:
- Proceedings of the National Academy of Sciences of the United States of America
- Additional Journal Information:
- Journal Name: Proceedings of the National Academy of Sciences of the United States of America Journal Volume: 112 Journal Issue: 34; Journal ID: ISSN 0027-8424
- Publisher:
- Proceedings of the National Academy of Sciences
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 36 MATERIALS SCIENCE; active matter; emergent pattern; confinement; colloids
Citation Formats
Spellings, Matthew, Engel, Michael, Klotsa, Daphne, Sabrina, Syeda, Drews, Aaron M., Nguyen, Nguyen H. P., Bishop, Kyle J. M., and Glotzer, Sharon C. Shape control and compartmentalization in active colloidal cells. United States: N. p., 2015.
Web. doi:10.1073/pnas.1513361112.
Spellings, Matthew, Engel, Michael, Klotsa, Daphne, Sabrina, Syeda, Drews, Aaron M., Nguyen, Nguyen H. P., Bishop, Kyle J. M., & Glotzer, Sharon C. Shape control and compartmentalization in active colloidal cells. United States. https://doi.org/10.1073/pnas.1513361112
Spellings, Matthew, Engel, Michael, Klotsa, Daphne, Sabrina, Syeda, Drews, Aaron M., Nguyen, Nguyen H. P., Bishop, Kyle J. M., and Glotzer, Sharon C. Fri .
"Shape control and compartmentalization in active colloidal cells". United States. https://doi.org/10.1073/pnas.1513361112.
@article{osti_1235147,
title = {Shape control and compartmentalization in active colloidal cells},
author = {Spellings, Matthew and Engel, Michael and Klotsa, Daphne and Sabrina, Syeda and Drews, Aaron M. and Nguyen, Nguyen H. P. and Bishop, Kyle J. M. and Glotzer, Sharon C.},
abstractNote = {Small autonomous machines like biological cells or soft robots can convert energy input into control of function and form. It is desired that this behavior emerges spontaneously and can be easily switched over time. For this purpose, in this paper we introduce an active matter system that is loosely inspired by biology and which we term an active colloidal cell. The active colloidal cell consists of a boundary and a fluid interior, both of which are built from identical rotating spinners whose activity creates convective flows. Similarly to biological cell motility, which is driven by cytoskeletal components spread throughout the entire volume of the cell, active colloidal cells are characterized by highly distributed energy conversion. We demonstrate that we can control the shape of the active colloidal cell and drive compartmentalization by varying the details of the boundary (hard vs. flexible) and the character of the spinners (passive vs. active). We report buckling of the boundary controlled by the pattern of boundary activity, as well as formation of core–shell and inverted Janus phase-separated configurations within the active cell interior. As the cell size is increased, the inverted Janus configuration spontaneously breaks its mirror symmetry. The result is a bubble–crescent configuration, which alternates between two degenerate states over time and exhibits collective migration of the fluid along the boundary. Finally, our results are obtained using microscopic, non–momentum-conserving Langevin dynamics simulations and verified via a phase-field continuum model coupled to a Navier–Stokes equation.},
doi = {10.1073/pnas.1513361112},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
number = 34,
volume = 112,
place = {United States},
year = {Fri Aug 07 00:00:00 EDT 2015},
month = {Fri Aug 07 00:00:00 EDT 2015}
}
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https://doi.org/10.1073/pnas.1513361112
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