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Title: Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling

Abstract

The plant hormone jasmonate plays crucial roles in regulating plant responses to herbivorous insects and microbial pathogens and is an important regulator of plant growth and development. Key mediators of jasmonate signalling include MYC transcription factors, which are repressed by jasmonate ZIM-domain (JAZ) transcriptional repressors in the resting state. In the presence of active jasmonate, JAZ proteins function as jasmonate co-receptors by forming a hormone-dependent complex with COI1, the F-box subunit of an SCF-type ubiquitin E3 ligase. The hormone-dependent formation of the COI1–JAZ co-receptor complex leads to ubiquitination and proteasome-dependent degradation of JAZ repressors and release of MYC proteins from transcriptional repression. The mechanism by which JAZ proteins repress MYC transcription factors and how JAZ proteins switch between the repressor function in the absence of hormone and the co-receptor function in the presence of hormone remain enigmatic. In this paper, we show that Arabidopsis MYC3 undergoes pronounced conformational changes when bound to the conserved Jas motif of the JAZ9 repressor. The Jas motif, previously shown to bind to hormone as a partly unwound helix, forms a complete α-helix that displaces the amino (N)-terminal helix of MYC3 and becomes an integral part of the MYC N-terminal fold. In this position, themore » Jas helix competitively inhibits MYC3 interaction with the MED25 subunit of the transcriptional Mediator complex. Finally, our structural and functional studies elucidate a dynamic molecular switch mechanism that governs the repression and activation of a major plant hormone pathway.« less

Authors:
 [1];  [2];  [3];  [4];  [5];  [6];  [3];  [7];  [8];  [5];  [9];  [10];  [3];  [11]
+ Show Author Affiliations
  1. Van Andel Research Inst. (VARI), Grand Rapids, MI (United States). Lab. of Structural Biology and Biochemistry. Lab. of Structural Sciences; Michigan State Univ., East Lansing, MI (United States). DOE Plant Research Lab.; Nanjing Agricultural Univ. (China). College of Plant Protection
  2. Michigan State Univ., East Lansing, MI (United States). DOE Plant Research Lab.; Western Michigan Univ., Kalamazoo, MI (United States). Dept. of Biological Sciences
  3. Van Andel Research Inst. (VARI), Grand Rapids, MI (United States). Lab. of Structural Biology and Biochemistry. Lab. of Structural Sciences
  4. Michigan State Univ., East Lansing, MI (United States). Dept. of Plant Biology. DOE Plant Research Lab.
  5. Scripps Research Inst., Jupiter, FL (United States). Dept. of Molecular Therapeutics. Translational Research Inst.
  6. Michigan State Univ., East Lansing, MI (United States). DOE Plant Research Lab.
  7. Van Andel Research Inst. (VARI), Grand Rapids, MI (United States). Lab. of Structural Biology and Biochemistry. Lab. of Structural Sciences; Zhejiang Sci-Tech Univ., Hangzhou (China). College of Life Sciences
  8. Northwestern Univ., Argonne, IL (United States). Synchrotron Research Center. Life Sciences Collaborative Access Team. Dept. of Molecular Pharmacology and Biological Chemistry
  9. Nanjing Agricultural Univ. (China). College of Plant Protection
  10. Van Andel Research Inst. (VARI), Grand Rapids, MI (United States). Lab. of Structural Biology and Biochemistry. Lab. of Structural Sciences; Chinese Academy of Sciences (CAS), Shanghai (China). Shanghai Inst. for Biological Sciences. Shanghai Inst. of Materia Medica. Center for Structure and Function of Drug Targets. VARI-SIMM Center. Key Lab. of Receptor Research
  11. Michigan State Univ., East Lansing, MI (United States). Dept. of Plant Biology. DOE Plant Research Lab. Howard Hughes Medical Inst.
Publication Date:
Research Org.:
Van Andel Research Inst. (VARI), Grand Rapids, MI (United States); Michigan State Univ., East Lansing, MI (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES); National Inst. of Health (NIH) (United States); Gordon and Betty Moore Foundation (United States); Van Andel Research Inst. (United States); Michigan Economic Development Corporation (United States); Michigan Technology Tri-Corridor (United States); Chinese Scholarship Council
Contributing Org.:
Nanjing Agricultural Univ. (China); Western Michigan Univ., Kalamazoo, MI (United States); Scripps Research Inst., Jupiter, FL (United States); Zhejiang Sci-Tech Univ., Hangzhou (China); Northwestern Univ., Argonne, IL (United States); Chinese Academy of Sciences (CAS), Shanghai (China)
OSTI Identifier:
1221449
Grant/Contract Number:  
FG02-91ER20021; AC02-06CH11357; R01 GM102545; R01AI060761; GBMF3037; 085P1000817
Resource Type:
Accepted Manuscript
Journal Name:
Nature (London)
Additional Journal Information:
Journal Name: Nature (London); Journal Volume: 525; Journal Issue: 7568; Journal ID: ISSN 0028-0836
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
ENGLISH
Subject:
59 BASIC BIOLOGICAL SCIENCES; Plant hormones; Structural biology; Plant signalling

Citation Formats

Zhang, Feng, Yao, Jian, Ke, Jiyuan, Zhang, Li, Lam, Vinh Q., Xin, Xiu-Fang, Zhou, X. Edward, Chen, Jian, Brunzelle, Joseph, Griffin, Patrick R., Zhou, Mingguo, Xu, H. Eric, Melcher, Karsten, and He, Sheng Yang. Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling. United States: N. p., 2015. Web. doi:10.1038/nature14661.
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Zhang, Feng, Yao, Jian, Ke, Jiyuan, Zhang, Li, Lam, Vinh Q., Xin, Xiu-Fang, Zhou, X. Edward, Chen, Jian, Brunzelle, Joseph, Griffin, Patrick R., Zhou, Mingguo, Xu, H. Eric, Melcher, Karsten, & He, Sheng Yang. Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling. United States. https://doi.org/10.1038/nature14661
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Zhang, Feng, Yao, Jian, Ke, Jiyuan, Zhang, Li, Lam, Vinh Q., Xin, Xiu-Fang, Zhou, X. Edward, Chen, Jian, Brunzelle, Joseph, Griffin, Patrick R., Zhou, Mingguo, Xu, H. Eric, Melcher, Karsten, and He, Sheng Yang. Mon . "Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling". United States. https://doi.org/10.1038/nature14661. https://www.osti.gov/servlets/purl/1221449.
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@article{osti_1221449,
title = {Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling},
author = {Zhang, Feng and Yao, Jian and Ke, Jiyuan and Zhang, Li and Lam, Vinh Q. and Xin, Xiu-Fang and Zhou, X. Edward and Chen, Jian and Brunzelle, Joseph and Griffin, Patrick R. and Zhou, Mingguo and Xu, H. Eric and Melcher, Karsten and He, Sheng Yang},
abstractNote = {The plant hormone jasmonate plays crucial roles in regulating plant responses to herbivorous insects and microbial pathogens and is an important regulator of plant growth and development. Key mediators of jasmonate signalling include MYC transcription factors, which are repressed by jasmonate ZIM-domain (JAZ) transcriptional repressors in the resting state. In the presence of active jasmonate, JAZ proteins function as jasmonate co-receptors by forming a hormone-dependent complex with COI1, the F-box subunit of an SCF-type ubiquitin E3 ligase. The hormone-dependent formation of the COI1–JAZ co-receptor complex leads to ubiquitination and proteasome-dependent degradation of JAZ repressors and release of MYC proteins from transcriptional repression. The mechanism by which JAZ proteins repress MYC transcription factors and how JAZ proteins switch between the repressor function in the absence of hormone and the co-receptor function in the presence of hormone remain enigmatic. In this paper, we show that Arabidopsis MYC3 undergoes pronounced conformational changes when bound to the conserved Jas motif of the JAZ9 repressor. The Jas motif, previously shown to bind to hormone as a partly unwound helix, forms a complete α-helix that displaces the amino (N)-terminal helix of MYC3 and becomes an integral part of the MYC N-terminal fold. In this position, the Jas helix competitively inhibits MYC3 interaction with the MED25 subunit of the transcriptional Mediator complex. Finally, our structural and functional studies elucidate a dynamic molecular switch mechanism that governs the repression and activation of a major plant hormone pathway.},
doi = {10.1038/nature14661},
journal = {Nature (London)},
number = 7568,
volume = 525,
place = {United States},
year = {Mon Aug 10 00:00:00 EDT 2015},
month = {Mon Aug 10 00:00:00 EDT 2015}
}
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Works referenced in this record:

A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors
journal, November 2009

  • Melcher, Karsten; Ng, Ley-Moy; Zhou, X. Edward
  • Nature, Vol. 462, Issue 7273
  • DOI: 10.1038/nature08613

The Arabidopsis bHLH Transcription Factors MYC3 and MYC4 Are Targets of JAZ Repressors and Act Additively with MYC2 in the Activation of Jasmonate Responses
journal, February 2011

  • Fernández-Calvo, Patricia; Chini, Andrea; Fernández-Barbero, Gemma
  • The Plant Cell, Vol. 23, Issue 2
  • DOI: 10.1105/tpc.110.080788

HDX Workbench: Software for the Analysis of H/D Exchange MS Data
journal, June 2012

  • Pascal, Bruce D.; Willis, Scooter; Lauer, Janelle L.
  • Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 9
  • DOI: 10.1007/s13361-012-0419-6

Refinement of Macromolecular Structures by the Maximum-Likelihood Method
journal, May 1997

  • Murshudov, G. N.; Vagin, A. A.; Dodson, E. J.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 53, Issue 3
  • DOI: 10.1107/S0907444996012255

Multifarious Roles of Intrinsic Disorder in Proteins Illustrate Its Broad Impact on Plant Biology
journal, January 2013

  • Sun, Xiaolin; Rikkerink, Erik H. A.; Jones, William T.
  • The Plant Cell, Vol. 25, Issue 1
  • DOI: 10.1105/tpc.112.106062

Social Network: JAZ Protein Interactions Expand Our Knowledge of Jasmonate Signaling
journal, January 2012

Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor
journal, October 2010

The Arabidopsis CORONATINE INSENSITIVE1 Protein Is a Jasmonate Receptor
journal, August 2009

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα
journal, February 2002

  • Xu, H. Eric; Stanley, Thomas B.; Montana, Valerie G.
  • Nature, Vol. 415, Issue 6873
  • DOI: 10.1038/415813a

The JAZ family of repressors is the missing link in jasmonate signalling
journal, July 2007

Jasmonates and related oxylipins in plant responses to pathogenesis and herbivory
journal, August 2003

  • Farmer, Edward E.; Alméras, Emmanuelle; Krishnamurthy, Venkatesh
  • Current Opinion in Plant Biology, Vol. 6, Issue 4
  • DOI: 10.1016/S1369-5266(03)00045-1

COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine
journal, May 2008

  • Katsir, L.; Schilmiller, A. L.; Staswick, P. E.
  • Proceedings of the National Academy of Sciences, Vol. 105, Issue 19
  • DOI: 10.1073/pnas.0802332105

The Mediator Complex Subunit PFT1 Is a Key Regulator of Jasmonate-Dependent Defense in Arabidopsis
journal, August 2009

  • Kidd, Brendan N.; Edgar, Cameron I.; Kumar, Krish K.
  • The Plant Cell, Vol. 21, Issue 8
  • DOI: 10.1105/tpc.109.066910

Jasmonate-inducible gene: what does it mean?
journal, February 2009

Jasmonate: Preventing the Maize Tassel from Getting in Touch with His Feminine Side
journal, February 2009

Alternative splicing expands the repertoire of dominant JAZ repressors of jasmonate signaling: Alternative splicing of Arabidopsis JAZ genes
journal, August 2010

XDS
journal, January 2010

  • Kabsch, Wolfgang
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2
  • DOI: 10.1107/S0907444909047337

Structure of trypanothione reductase from Crithidia fasciculata at 2.6 Å resolution; enzyme–NADP interactions at 2.8 Å resolution
journal, March 1994

  • Bailey, S.; Fairlamb, A. H.; Hunter, W. N.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 50, Issue 2
  • DOI: 10.1107/S0907444993011898

JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
journal, July 2007

  • Thines, Bryan; Katsir, Leron; Melotto, Maeli
  • Nature, Vol. 448, Issue 7154
  • DOI: 10.1038/nature05960

Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade
journal, April 2012

  • Yang, D. -L.; Yao, J.; Mei, C. -S.
  • Proceedings of the National Academy of Sciences, Vol. 109, Issue 19
  • DOI: 10.1073/pnas.1201616109

Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis
journal, June 2007

Coot model-building tools for molecular graphics
journal, November 2004

  • Emsley, Paul; Cowtan, Kevin
  • Acta Crystallographica Section D Biological Crystallography, Vol. 60, Issue 12, p. 2126-2132
  • DOI: 10.1107/S0907444904019158

The Jasmonate Pathway
journal, May 2002

Recent advances and emerging trends in plant hormone signalling
journal, June 2009

Structure and function of transcriptional activation domains
journal, April 1995

A Downstream Mediator in the Growth Repression Limb of the Jasmonate Pathway
journal, August 2007

  • Yan, Yuanxin; Stolz, Stéphanie; Chételat, Aurore
  • The Plant Cell, Vol. 19, Issue 8
  • DOI: 10.1105/tpc.107.050708

MEDIATOR25 Acts as an Integrative Hub for the Regulation of Jasmonate-Responsive Gene Expression in Arabidopsis
journal, July 2012

  • Çevik, Volkan; Kidd, Brendan N.; Zhang, Peijun
  • Plant Physiology, Vol. 160, Issue 1
  • DOI: 10.1104/pp.112.202697

MYC2: The Master in Action
journal, May 2013

  • Kazan, Kemal; Manners, John M.
  • Molecular Plant, Vol. 6, Issue 3
  • DOI: 10.1093/mp/sss128

Structural basis for RNA recognition by a dimeric PPR-protein complex
journal, November 2013

  • Ke, Jiyuan; Chen, Run-Ze; Ban, Ting
  • Nature Structural & Molecular Biology, Vol. 20, Issue 12
  • DOI: 10.1038/nsmb.2710

Preparation of selenomethionyl proteins for phase determination
book, January 1997

Transcription factor-dependent nuclear localization of a transcriptional repressor in jasmonate hormone signaling
journal, November 2012

  • Withers, J.; Yao, J.; Mecey, C.
  • Proceedings of the National Academy of Sciences, Vol. 109, Issue 49
  • DOI: 10.1073/pnas.1210054109

(+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate
journal, April 2009

  • Fonseca, Sandra; Chini, Andrea; Hamberg, Mats
  • Nature Chemical Biology, Vol. 5, Issue 5
  • DOI: 10.1038/nchembio.161

NINJA connects the co-repressor TOPLESS to jasmonate signalling
journal, April 2010

  • Pauwels, Laurens; Barbero, Gemma Fernández; Geerinck, Jan
  • Nature, Vol. 464, Issue 7289
  • DOI: 10.1038/nature08854

Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

Probing Protein Ligand Interactions by Automated Hydrogen/Deuterium Exchange Mass Spectrometry
journal, February 2006

  • Chalmers, Michael J.; Busby, Scott A.; Pascal, Bruce D.
  • Analytical Chemistry, Vol. 78, Issue 4
  • DOI: 10.1021/ac051294f

Dominant Alleles of the Basic Helix-Loop-Helix Transcription Factor ATR2 Activate Stress-Responsive Genes in Arabidopsis
journal, July 2002

HDX Workbench: Software for the Analysis of H/D Exchange MS Data
journal, June 2012

  • Pascal, Bruce D.; Willis, Scooter; Lauer, Janelle L.
  • Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 9
  • DOI: 10.1007/s13361-012-0419-6

Jasmonate-inducible gene: what does it mean?
journal, February 2009

A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors
journal, November 2009

  • Melcher, Karsten; Ng, Ley-Moy; Zhou, X. Edward
  • Nature, Vol. 462, Issue 7273
  • DOI: 10.1038/nature08613

Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis
journal, June 2007

Structural basis for RNA recognition by a dimeric PPR-protein complex
journal, November 2013

  • Ke, Jiyuan; Chen, Run-Ze; Ban, Ting
  • Nature Structural & Molecular Biology, Vol. 20, Issue 12
  • DOI: 10.1038/nsmb.2710

COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine
journal, May 2008

  • Katsir, L.; Schilmiller, A. L.; Staswick, P. E.
  • Proceedings of the National Academy of Sciences, Vol. 105, Issue 19
  • DOI: 10.1073/pnas.0802332105

Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade
journal, April 2012

  • Yang, D. -L.; Yao, J.; Mei, C. -S.
  • Proceedings of the National Academy of Sciences, Vol. 109, Issue 19
  • DOI: 10.1073/pnas.1201616109

Dominant Alleles of the Basic Helix-Loop-Helix Transcription Factor ATR2 Activate Stress-Responsive Genes in Arabidopsis
journal, July 2002

MYC2: The Master in Action
journal, May 2013

  • Kazan, Kemal; Manners, John M.
  • Molecular Plant, Vol. 6, Issue 3
  • DOI: 10.1093/mp/sss128

A Downstream Mediator in the Growth Repression Limb of the Jasmonate Pathway
journal, August 2007

  • Yan, Yuanxin; Stolz, Stéphanie; Chételat, Aurore
  • The Plant Cell, Vol. 19, Issue 8
  • DOI: 10.1105/tpc.107.050708

Multifarious Roles of Intrinsic Disorder in Proteins Illustrate Its Broad Impact on Plant Biology
journal, January 2013

  • Sun, Xiaolin; Rikkerink, Erik H. A.; Jones, William T.
  • The Plant Cell, Vol. 25, Issue 1
  • DOI: 10.1105/tpc.112.106062

The Jasmonate Pathway
journal, May 2002

Jasmonate: Preventing the Maize Tassel from Getting in Touch with His Feminine Side
journal, February 2009

Social Network: JAZ Protein Interactions Expand Our Knowledge of Jasmonate Signaling
journal, January 2012

Plant mediator
journal, June 2010

  • Kidd, Brendan N.; Aitken, Elizabeth A.; Schenk, Peer M.
  • Plant Signaling & Behavior, Vol. 5, Issue 6
  • DOI: 10.4161/psb.5.6.11647
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    Works referencing / citing this record:

    Identification of TIFY/JAZ family genes in Solanum lycopersicum and their regulation in response to abiotic stresses
    journal, June 2017

    The OsJAZ1 degron modulates jasmonate signaling sensitivity during rice development
    journal, January 2019

    • Tian, Jiaqi; Cao, Lichun; Chen, Xiaofei
    • Development, Vol. 146, Issue 4
    • DOI: 10.1242/dev.173419

    Salt-inducible expression of OsJAZ8 improves resilience against salt-stress
    journal, November 2018

    • Peethambaran, Preshobha K.; Glenz, René; Höninger, Sabrina
    • BMC Plant Biology, Vol. 18, Issue 1
    • DOI: 10.1186/s12870-018-1521-0

    Design of a bacterial speck resistant tomato by CRISPR/Cas9-mediated editing of SlJAZ2
    journal, October 2018

    • Ortigosa, Andrés; Gimenez-Ibanez, Selena; Leonhardt, Nathalie
    • Plant Biotechnology Journal, Vol. 17, Issue 3
    • DOI: 10.1111/pbi.13006

    SmJAZ8 acts as a core repressor regulating JA-induced biosynthesis of salvianolic acids and tanshinones in Salvia miltiorrhiza hairy roots
    journal, December 2017

    • Pei, Tianlin; Ma, Pengda; Ding, Kai
    • Journal of Experimental Botany, Vol. 69, Issue 7
    • DOI: 10.1093/jxb/erx484

    ZmMADS47 Regulates Zein Gene Transcription through Interaction with Opaque2
    journal, April 2016

    A Novel Sweetpotato Transcription Factor Gene IbMYB116 Enhances Drought Tolerance in Transgenic Arabidopsis
    journal, August 2019

    An effector from cotton bollworm oral secretion impairs host plant defense signaling
    journal, June 2019

    • Chen, Chun-Yu; Liu, Yao-Qian; Song, Wei-Meng
    • Proceedings of the National Academy of Sciences, Vol. 116, Issue 28
    • DOI: 10.1073/pnas.1905471116

    Genome-wide survey of the bHLH super gene family in Brassica napus
    journal, March 2020

    Genome-Wide Identification and Characterization of the JAZ Gene Family in Rubber Tree (Hevea brasiliensis)
    journal, May 2019

    Alternative splicing of OsLG3b controls grain length and yield in japonica rice
    journal, March 2018

    • Yu, Jianping; Miao, Jinli; Zhang, Zhanying
    • Plant Biotechnology Journal, Vol. 16, Issue 9
    • DOI: 10.1111/pbi.12903

    PatJAZ6 Acts as a Repressor Regulating JA-Induced Biosynthesis of Patchouli Alcohol in Pogostemon Cablin
    journal, November 2019

    • Wang, Xiaobing; Chen, Xiuzhen; Zhong, Liting
    • International Journal of Molecular Sciences, Vol. 20, Issue 23
    • DOI: 10.3390/ijms20236038

    The Ubiquitin System and Jasmonate Signaling
    journal, January 2016

    • Nagels Durand, Astrid; Pauwels, Laurens; Goossens, Alain
    • Plants, Vol. 5, Issue 1
    • DOI: 10.3390/plants5010006

    A Chimeric IDD4 Repressor Constitutively Induces Immunity in Arabidopsis via the Modulation of Salicylic Acid and Jasmonic Acid Homeostasis
    journal, April 2019

    • V�lz, Ronny; Kim, Soon-Kap; Mi, Jianing
    • Plant and Cell Physiology, Vol. 60, Issue 7
    • DOI: 10.1093/pcp/pcz057

    Ligand-receptor co-evolution shaped the jasmonate pathway in land plants
    journal, April 2018

    • Monte, Isabel; Ishida, Sakiko; Zamarreño, Angel M.
    • Nature Chemical Biology, Vol. 14, Issue 5
    • DOI: 10.1038/s41589-018-0033-4

    Jasmonate action in plant defense against insects
    journal, April 2019

    • Wang, Jiaojiao; Wu, Dewei; Wang, Youping
    • Journal of Experimental Botany, Vol. 70, Issue 13
    • DOI: 10.1093/jxb/erz174

    Overexpression of OsMYC2 Results in the Up-Regulation of Early JA-Rresponsive Genes and Bacterial Blight Resistance in Rice
    journal, May 2016

    • Uji, Yuya; Taniguchi, Shiduku; Tamaoki, Daisuke
    • Plant and Cell Physiology, Vol. 57, Issue 9
    • DOI: 10.1093/pcp/pcw101

    The JA‐pathway MYC transcription factors regulate photomorphogenic responses by targeting HY5 gene expression
    journal, January 2020

    • Ortigosa, Andrés; Fonseca, Sandra; Franco‐Zorrilla, José M.
    • The Plant Journal, Vol. 102, Issue 1
    • DOI: 10.1111/tpj.14618

    Ubiquitylation in plants: signaling hub for the integration of environmental signals
    journal, May 2018

    • Miricescu, Alexandra; Goslin, Kevin; Graciet, Emmanuelle
    • Journal of Experimental Botany, Vol. 69, Issue 19
    • DOI: 10.1093/jxb/ery165

    Signaling Crosstalk between Salicylic Acid and Ethylene/Jasmonate in Plant Defense: Do We Understand What They Are Whispering?
    journal, February 2019

    • Li, Ning; Han, Xiao; Feng, Dan
    • International Journal of Molecular Sciences, Vol. 20, Issue 3
    • DOI: 10.3390/ijms20030671

    Host target modification as a strategy to counter pathogen hijacking of the jasmonate hormone receptor
    journal, November 2015

    • Zhang, Li; Yao, Jian; Withers, John
    • Proceedings of the National Academy of Sciences, Vol. 112, Issue 46
    • DOI: 10.1073/pnas.1510745112

    Reconstitution of the Jasmonate Signaling Pathway in Plant Protoplasts
    journal, November 2019

    Oligogalacturonide production upon Arabidopsis thaliana – Botrytis cinerea interaction
    journal, September 2019

    • Voxeur, Aline; Habrylo, Olivier; Guénin, Stéphanie
    • Proceedings of the National Academy of Sciences, Vol. 116, Issue 39
    • DOI: 10.1073/pnas.1900317116

    Mediator subunit MED25 links the jasmonate receptor to transcriptionally active chromatin
    journal, October 2017

    • An, Chunpeng; Li, Lin; Zhai, Qingzhe
    • Proceedings of the National Academy of Sciences, Vol. 114, Issue 42
    • DOI: 10.1073/pnas.1710885114

    JAZ repressors of metabolic defense promote growth and reproductive fitness in Arabidopsis
    journal, October 2018

    • Guo, Qiang; Yoshida, Yuki; Major, Ian T.
    • Proceedings of the National Academy of Sciences, Vol. 115, Issue 45
    • DOI: 10.1073/pnas.1811828115

    JAZ2 controls stomata dynamics during bacterial invasion
    journal, December 2016

    • Gimenez-Ibanez, Selena; Boter, Marta; Ortigosa, Andrés
    • New Phytologist, Vol. 213, Issue 3
    • DOI: 10.1111/nph.14354

    Viral effector protein manipulates host hormone signaling to attract insect vectors
    journal, January 2017

    • Wu, Dewei; Qi, Tiancong; Li, Wan-Xiang
    • Cell Research, Vol. 27, Issue 3
    • DOI: 10.1038/cr.2017.2

    JAZ4 is involved in plant defense, growth, and development in Arabidopsis
    journal, November 2019

    • Oblessuc, Paula R.; Obulareddy, Nisita; DeMott, Logan
    • The Plant Journal, Vol. 101, Issue 2
    • DOI: 10.1111/tpj.14548

    The fungal phytotoxin lasiojasmonate A activates the plant jasmonic acid pathway
    journal, March 2018

    • Chini, Andrea; Cimmino, Alessio; Masi, Marco
    • Journal of Experimental Botany, Vol. 69, Issue 12
    • DOI: 10.1093/jxb/ery114

    Systems genetics reveals a transcriptional network associated with susceptibility in the maize-grey leaf spot pathosystem
    journal, February 2017

    • Christie, Nanette; Myburg, Alexander A.; Joubert, Fourie
    • The Plant Journal, Vol. 89, Issue 4
    • DOI: 10.1111/tpj.13419

    Jasmonate action in plant growth and development
    journal, February 2017

    • Huang, Huang; Liu, Bei; Liu, Liangyu
    • Journal of Experimental Botany, Vol. 68, Issue 6
    • DOI: 10.1093/jxb/erw495

    Salt stress response triggers activation of the jasmonate signaling pathway leading to inhibition of cell elongation in Arabidopsis primary root
    journal, May 2016

    • Valenzuela, Camilo E.; Acevedo-Acevedo, Orlando; Miranda, Giovanna S.
    • Journal of Experimental Botany, Vol. 67, Issue 14
    • DOI: 10.1093/jxb/erw202

    Jasmonates: biosynthesis, metabolism, and signaling by proteins activating and repressing transciption
    journal, December 2016

    Differential expression of microRNAs in tomato leaves treated with different light qualities
    journal, January 2020

    Genome-Wide Identification and Characterization of JAZ Protein Family in Two Petunia Progenitors
    journal, July 2019

    An EDS1 EP-domain surface mediating timely transcriptional reprogramming of immunity genes
    preprint, July 2018

    • Bhandari, Deepak D.; Lapin, Dmitry; Kracher, Barbara
    • DOI: 10.1101/362921

    Molecular assembly of rhodopsin with G protein-coupled receptor kinases
    journal, May 2017

    • He, Yuanzheng; Gao, Xiang; Goswami, Devrishi
    • Cell Research, Vol. 27, Issue 6
    • DOI: 10.1038/cr.2017.72

    The plant Mediator complex and its role in jasmonate signaling
    journal, May 2019

    • Zhai, Qingzhe; Li, Chuanyou
    • Journal of Experimental Botany, Vol. 70, Issue 13
    • DOI: 10.1093/jxb/erz233

    Specificity of MYB interactions relies on motifs in ordered and disordered contexts
    journal, August 2019

    • Millard, Peter S.; Weber, Konrad; Kragelund, Birthe B.
    • Nucleic Acids Research, Vol. 47, Issue 18
    • DOI: 10.1093/nar/gkz691

    The ubiquitin‐proteasome system in plant responses to environments
    journal, August 2019

    • Xu, Fa‐Qing; Xue, Hong‐Wei
    • Plant, Cell & Environment, Vol. 42, Issue 10
    • DOI: 10.1111/pce.13633

    Jasmonate regulates leaf senescence and tolerance to cold stress: crosstalk with other phytohormones
    journal, February 2017

    • Hu, Yanru; Jiang, Yanjuan; Han, Xiao
    • Journal of Experimental Botany, Vol. 68, Issue 6
    • DOI: 10.1093/jxb/erx004

    Construction and characterization of a high-quality cDNA library of Cymbidium faberi suitable for yeast one- and two-hybrid assays
    journal, January 2020

    Comparative functional genomics analysis of bHLH gene family in rice, maize and wheat
    journal, November 2018

    Regulation of growth-defense balance by the JASMONATE ZIM-DOMAIN (JAZ)-MYC transcriptional module
    journal, June 2017

    • Major, Ian T.; Yoshida, Yuki; Campos, Marcelo L.
    • New Phytologist, Vol. 215, Issue 4
    • DOI: 10.1111/nph.14638

    ETHYLENE RESPONSE FACTOR 115 integrates jasmonate and cytokinin signaling machineries to repress adventitious rooting in Arabidopsis
    journal, August 2020

    • Lakehal, Abdellah; Dob, Asma; Rahneshan, Zahra
    • New Phytologist, Vol. 228, Issue 5
    • DOI: 10.1111/nph.16794

    Salt-inducible expression of OsJAZ8 improves resilience against salt-stress
    text, January 2018

    Integrated multi-omics framework of the plant response to jasmonic acid
    journal, March 2020

    Molecular assembly of rhodopsin with G protein-coupled receptor kinases
    journal, May 2017

    • He, Yuanzheng; Gao, Xiang; Goswami, Devrishi
    • Cell Research, Vol. 27, Issue 6
    • DOI: 10.1038/cr.2017.72

    An effector from cotton bollworm oral secretion impairs host plant defense signaling
    journal, June 2019

    • Chen, Chun-Yu; Liu, Yao-Qian; Song, Wei-Meng
    • Proceedings of the National Academy of Sciences, Vol. 116, Issue 28
    • DOI: 10.1073/pnas.1905471116

    Salt stress response triggers activation of the jasmonate signaling pathway leading to inhibition of cell elongation in Arabidopsis primary root
    journal, May 2016

    • Valenzuela, Camilo E.; Acevedo-Acevedo, Orlando; Miranda, Giovanna S.
    • Journal of Experimental Botany, Vol. 67, Issue 14
    • DOI: 10.1093/jxb/erw202

    Jasmonate – a blooming decade
    journal, March 2017

    • Zhu, Ziqiang; Napier, Richard
    • Journal of Experimental Botany, Vol. 68, Issue 6
    • DOI: 10.1093/jxb/erx068

    The plant Mediator complex and its role in jasmonate signaling
    journal, May 2019

    • Zhai, Qingzhe; Li, Chuanyou
    • Journal of Experimental Botany, Vol. 70, Issue 13
    • DOI: 10.1093/jxb/erz233

    Specificity of MYB interactions relies on motifs in ordered and disordered contexts
    journal, August 2019

    • Millard, Peter S.; Weber, Konrad; Kragelund, Birthe B.
    • Nucleic Acids Research, Vol. 47, Issue 18
    • DOI: 10.1093/nar/gkz691

    A plant's balance of growth and defense - revisited
    journal, August 2017

    Differential expression of microRNAs in tomato leaves treated with different light qualities
    journal, January 2020

    Salt-inducible expression of OsJAZ8 improves resilience against salt-stress
    journal, November 2018

    • Peethambaran, Preshobha K.; Glenz, René; Höninger, Sabrina
    • BMC Plant Biology, Vol. 18, Issue 1
    • DOI: 10.1186/s12870-018-1521-0

    Comparative functional genomics analysis of bHLH gene family in rice, maize and wheat
    journal, November 2018

    Construction and characterization of a high-quality cDNA library of Cymbidium faberi suitable for yeast one- and two-hybrid assays
    journal, January 2020

    Identification of TIFY/JAZ family genes in Solanum lycopersicum and their regulation in response to abiotic stresses
    journal, June 2017

    The Multitalented MEDIATOR25
    journal, June 2017

    A Novel Sweetpotato Transcription Factor Gene IbMYB116 Enhances Drought Tolerance in Transgenic Arabidopsis
    journal, August 2019

    Reconstitution of the Jasmonate Signaling Pathway in Plant Protoplasts
    journal, November 2019

    Signaling Crosstalk between Salicylic Acid and Ethylene/Jasmonate in Plant Defense: Do We Understand What They Are Whispering?
    journal, February 2019

    • Li, Ning; Han, Xiao; Feng, Dan
    • International Journal of Molecular Sciences, Vol. 20, Issue 3
    • DOI: 10.3390/ijms20030671

    The Ubiquitin System and Jasmonate Signaling
    journal, January 2016

    • Nagels Durand, Astrid; Pauwels, Laurens; Goossens, Alain
    • Plants, Vol. 5, Issue 1
    • DOI: 10.3390/plants5010006

    Stimulation of Insect Herbivory by Elevated Temperature Outweighs Protection by the Jasmonate Pathway
    journal, February 2020

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