Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes

D’Aléo, Anthony; Moore, Evan G.; Xu, Jide; Daumann, Lena J.; Raymond, Kenneth N.

doi:10.1021/acs.inorgchem.5b00748

Title: Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes

Authors:

D’Aléo, Anthony ^[1]; Moore, Evan G. ^[1]; Xu, Jide ^[1]; Daumann, Lena J. ^[1]; Raymond, Kenneth N. ^[1]

Department of Chemistry, University of California, Berkeley, California 94720-1460, United States, Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States

Publication Date:: Tue Jul 07 00:00:00 EDT 2015

Sponsoring Org.:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

OSTI Identifier:: 1213600

Resource Type:: Published Article

Journal Name:: Inorganic Chemistry

Additional Journal Information:: Journal Name: Inorganic Chemistry Journal Volume: 54 Journal Issue: 14; Journal ID: ISSN 0020-1669

Publisher:: American Chemical Society

Country of Publication:: United States

Language:: English

Citation Formats


                    D’Aléo, Anthony, Moore, Evan G., Xu, Jide, Daumann, Lena J., and Raymond, Kenneth N. Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes.  United States: N. p., 2015. 
Web.  doi:10.1021/acs.inorgchem.5b00748.

Copy to clipboard


                    D’Aléo, Anthony, Moore, Evan G., Xu, Jide, Daumann, Lena J., & Raymond, Kenneth N. Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes.  United States.  https://doi.org/10.1021/acs.inorgchem.5b00748

Copy to clipboard


                    D’Aléo, Anthony, Moore, Evan G., Xu, Jide, Daumann, Lena J., and Raymond, Kenneth N. Tue .  
"Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes".  United States.  https://doi.org/10.1021/acs.inorgchem.5b00748.

Copy to clipboard


                    
@article{osti_1213600,

  title        = {Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes},

  author       = {D’Aléo, Anthony and Moore, Evan G. and Xu, Jide and Daumann, Lena J. and Raymond, Kenneth N.},

  abstractNote = {},

  doi          = {10.1021/acs.inorgchem.5b00748},

  journal      = {Inorganic Chemistry},

  number       = 14,

  volume       = 54,

  place        = {United States},

  year         = {Tue Jul 07 00:00:00 EDT 2015},

  month        = {Tue Jul 07 00:00:00 EDT 2015}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Publisher's Version of Record
https://doi.org/10.1021/acs.inorgchem.5b00748

Other availability

Search WorldCat to find libraries that may hold this journal

Citation Metrics:

Cited by: 15 works

Citation information provided by
Web of Science

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Design of Lanthanide Complex Probes for Highly Sensitive Time-Resolved Fluorometric Detection Methods and Its Application to Biochemical, Environmental and Clinical Analyses
journal, October 2006

Matsuya, Takeshi; Hoshino, Nobuhiro; Okuyama, Tsuneo
Current Analytical Chemistry, Vol. 2, Issue 4
DOI: 10.2174/157341106778520526

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging
journal, January 2014

Butler, Stephen J.; Lamarque, Laurent; Pal, Robert
Chemical Science, Vol. 5, Issue 5
DOI: 10.1039/c3sc53056f

Substituent Effects on Gd(III)-Based MRI Contrast Agents: Optimizing the Stability and Selectivity of the Complex and the Number of Coordinated Water Molecules¹
journal, October 2006

Pierre, Valerie C.; Botta, Mauro; Aime, Silvio
Inorganic Chemistry, Vol. 45, Issue 20, p. 8355-8364
DOI: 10.1021/ic061262q

Aryl-Bridged 1-Hydroxypyridin-2-one: Sensitizer Ligands for Eu(III)
journal, July 2008

D’Aléo, Anthony; Xu, Jide; Moore, Evan G.
Inorganic Chemistry, Vol. 47, Issue 14
DOI: 10.1021/ic8003189

From Antenna to Assay: Lessons Learned in Lanthanide Luminescence
journal, April 2009

Moore, Evan G.; Samuel, Amanda P. S.; Raymond, Kenneth N.
Accounts of Chemical Research, Vol. 42, Issue 4
DOI: 10.1021/ar800211j

New Insights into Structure and Luminescence of Eu ^III and Sm ^III Complexes of the 3,4,3-LI(1,2-HOPO) Ligand
journal, February 2015

Daumann, Lena J.; Tatum, David S.; Snyder, Benjamin E. R.
Journal of the American Chemical Society, Vol. 137, Issue 8
DOI: 10.1021/ja5116524

Optical Absorption Intensities of Rare-Earth Ions
journal, August 1962

Judd, B. R.
Physical Review, Vol. 127, Issue 3
DOI: 10.1103/PhysRev.127.750

Gadolinium(III) 1,2-Hydroxypyridonate-Based Complexes: Toward MRI Contrast Agents of High Relaxivity¹
journal, September 2004

Xu, Jide; Churchill, David G.; Botta, Mauro
Inorganic Chemistry, Vol. 43, Issue 18, p. 5492-5494
DOI: 10.1021/ic049028s

The emission spectrum and the radiative lifetime of Eu3+ in luminescent lanthanide complexes
journal, March 2002

Werts, Martinus H. V.; Jukes, Ronald T. F.; Verhoeven, Jan W.
Physical Chemistry Chemical Physics, Vol. 4, Issue 9
DOI: 10.1039/b107770h

New Lanthanide Complexes with Antioxidant Activity
journal, July 2008

Kostova, Irena; Traykova, Maria; Rastogi, Vinod
Medicinal Chemistry, Vol. 4, Issue 4
DOI: 10.2174/157340608784872181

50th anniversary of the Judd–Ofelt theory: An experimentalist's view of the formalism and its application
journal, April 2013

Hehlen, Markus P.; Brik, Mikhail G.; Krämer, Karl W.
Journal of Luminescence, Vol. 136
DOI: 10.1016/j.jlumin.2012.10.035

Synthesis, characterization, and antioxidative activity of new vitamin B6 triethanolamine rare earth (III) complexes
journal, November 1993

Yang, KeWu; Wang, LiuFang; Wu, JiGui
Journal of Inorganic Biochemistry, Vol. 52, Issue 2
DOI: 10.1016/0162-0134(93)85031-3

Highly Luminescent and Stable Hydroxypyridinonate Complexes: A Step Towards New Curium Decontamination Strategies
journal, July 2014

Sturzbecher-Hoehne, Manuel; Kullgren, Birgitta; Jarvis, Erin E.
Chemistry - A European Journal, Vol. 20, Issue 32
DOI: 10.1002/chem.201402103

Modulating the Photophysical Properties of Azamacrocyclic Europium Complexes with Charge-Transfer Antenna Chromophores
journal, June 2011

Bourdolle, Adrien; Allali, Mustapha; Mulatier, Jean-Christophe
Inorganic Chemistry, Vol. 50, Issue 11
DOI: 10.1021/ic200227b

Lanthanide Luminescence for Biomedical Analyses and Imaging
journal, May 2010

Bünzli, Jean-Claude G.
Chemical Reviews, Vol. 110, Issue 5
DOI: 10.1021/cr900362e

Intensities of Crystal Spectra of Rare‐Earth Ions
journal, August 1962

Ofelt, G. S.
The Journal of Chemical Physics, Vol. 37, Issue 3
DOI: 10.1063/1.1701366

NMR Structure Determination of Protein−Ligand Complexes by Lanthanide Labeling
journal, March 2007

Pintacuda, Guido; John, Michael; Su, Xun-Cheng
Accounts of Chemical Research, Vol. 40, Issue 3
DOI: 10.1021/ar050087z

Primer on gadolinium chemistry
journal, December 2009

Sherry, A. Dean; Caravan, Peter; Lenkinski, Robert E.
Journal of Magnetic Resonance Imaging, Vol. 30, Issue 6
DOI: 10.1002/jmri.21966

Correlation between the lowest triplet state energy level of the ligand and lanthanide(III) luminescence quantum yield
journal, September 1997

Latva, Martti; Takalo, Harri; Mukkala, Veli-Matti
Journal of Luminescence, Vol. 75, Issue 2
DOI: 10.1016/S0022-2313(97)00113-0

Of Folding and Function: Understanding Active-Site Context through Metalloenzyme Design
journal, December 2006

Harris, Kinesha L.; Lim, Sunghyuk; Franklin, Sonya J.
Inorganic Chemistry, Vol. 45, Issue 25
DOI: 10.1021/ic060877k

Diverse Solid-State and Solution Structures within a Series of Hexaamine Dicopper(II) Complexes
journal, March 2001

Bernhardt, Paul V.
Inorganic Chemistry, Vol. 40, Issue 6
DOI: 10.1021/ic000928s

Development of Decorporation Agents for the Actinides
journal, October 1998

Durbin, P. W.; Kullgren, B.; Xu, J.
Radiation Protection Dosimetry, Vol. 79, Issue 1
DOI: 10.1093/oxfordjournals.rpd.a032445

Toward Optimized High-Relaxivity MRI Agents: The Effect of Ligand Basicity on the Thermodynamic Stability of Hexadentate Hydroxypyridonate/Catecholate Gadolinium(III) Complexes
journal, August 2003

Doble, Dan M. J.; Melchior, Marco; O'Sullivan, Brendon
Inorganic Chemistry, Vol. 42, Issue 16, p. 4930-4937
DOI: 10.1021/ic026240s

Lanthanide Luminescent Bioprobes (LLBs)
journal, February 2009

Bünzli, Jean-Claude G.
Chemistry Letters, Vol. 38, Issue 2
DOI: 10.1246/cl.2009.104

Lanthanide-based luminescence probes and time-resolved luminescence bioassays
journal, May 2006

Yuan, Jingli; Wang, Guilan
TrAC Trends in Analytical Chemistry, Vol. 25, Issue 5, p. 490-500
DOI: 10.1016/j.trac.2005.11.013

Sequence-Specific and Stereospecific Assignment of Methyl Groups Using Paramagnetic Lanthanides
journal, November 2007

John, Michael; Schmitz, Christophe; Park, Ah Young
Journal of the American Chemical Society, Vol. 129, Issue 44
DOI: 10.1021/ja0744753

Characterization, HPLC method development and impurity identification for 3,4,3-LI(1,2-HOPO), a potent actinide chelator for radionuclide decorporation
journal, January 2015

Liu, Mingtao; Wang, Jennie; Wu, Xiaogang
Journal of Pharmaceutical and Biomedical Analysis, Vol. 102
DOI: 10.1016/j.jpba.2014.10.015

Intriguing aspects of lanthanide luminescence
journal, January 2013

Bünzli, Jean-Claude G.; Eliseeva, Svetlana V.
Chemical Science, Vol. 4, Issue 5
DOI: 10.1039/c3sc22126a

Very bright europium complexes that stain cellular mitochondria
journal, January 2013

Walton, James W.; Bourdolle, Adrien; Butler, Stephen J.
Chemical Communications, Vol. 49, Issue 16
DOI: 10.1039/c2cc35247h

Efficient Sensitization of Europium, Ytterbium, and Neodymium Functionalized Tris-Dipicolinate Lanthanide Complexes through Tunable Charge-Transfer Excited States
journal, November 2008

D’Aléo, Anthony; Picot, Alexandre; Beeby, Andrew
Inorganic Chemistry, Vol. 47, Issue 22
DOI: 10.1021/ic8012969

“Cymothoe sangaris”: An Extremely Stable and Highly Luminescent 1,2-Hydroxypyridinonate Chelate of Eu(III)
July 2006

Moore, Evan G.; Xu, Jide; Jocher, Christoph J.
Journal of the American Chemical Society, Vol. 128, Issue 33, p. 10648-10649
DOI: 10.1021/ja062597+

Luminescent Lanthanide Cryptates: from the Bench to the Bedside
journal, December 2013

Zwier, Jurriaan M.; Bazin, Hervé; Lamarque, Laurent
Inorganic Chemistry, Vol. 53, Issue 4
DOI: 10.1021/ic402234k

LANCE™: Homogeneous Assay Platform for HTS
journal, December 1999

Hemmila, Ilkka
Journal of Biomolecular Screening, Vol. 4, Issue 6, p. 303-307
DOI: 10.1177/108705719900400604

A Time-Resolved Fluorescence Immunoassay (DELFIA) Increases the Sensitivity of Antigen-Driven Cytokine Detection
journal, January 2003

Allicotti, Gina; Borras, Eva; Pinilla, Clemencia
Journal of Immunoassay and Immunochemistry, Vol. 24, Issue 4, p. 345-358
DOI: 10.1081/IAS-120025772

HTRF® Technology
journal, December 1999

Mathis, Gérard
Journal of Biomolecular Screening, Vol. 4, Issue 6
DOI: 10.1177/108705719900400605

Highly Luminescent Lanthanide Complexes of 1-Hydroxy-2-pyridinones
journal, April 2008

Moore, Evan G.; Xu, Jide; Jocher, Christoph J.
Inorganic Chemistry, Vol. 47, Issue 8
DOI: 10.1021/ic702144n

An Octadentate Luminescent Eu(III) 1,2-HOPO Chelate with Potent Aqueous Stability
journal, July 2007

Moore, Evan G.; Jocher, Christoph J.; Xu, Jide
Inorganic Chemistry, Vol. 46, Issue 14, p. 5468-5470
DOI: 10.1021/ic700364t

Water-Soluble 2-Hydroxyisophthalamides for Sensitization of Lanthanide Luminescence
journal, September 2008

Samuel, Amanda P. S.; Moore, Evan G.; Melchior, Marco
Inorganic Chemistry, Vol. 47, Issue 17
DOI: 10.1021/ic800328g

Alternative Chelator for ⁸⁹ Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO)
journal, December 2013

Deri, Melissa A.; Ponnala, Shashikanth; Zeglis, Brian M.
Journal of Medicinal Chemistry, Vol. 57, Issue 11
DOI: 10.1021/jm500389b

A Water-Soluble Pybox Derivative and Its Highly Luminescent Lanthanide Ion Complexes
journal, April 2012

de Bettencourt-Dias, Ana; Barber, Patrick S.; Bauer, Sebastian
Journal of the American Chemical Society, Vol. 134, Issue 16
DOI: 10.1021/ja209572m

Intramolecular sensitisation of lanthanide(iii) luminescence by acetophenone-containing ligands: the critical effect of para-substituents and solvent
journal, November 2001

Beeby, Andrew; Bushby, Lisa M.; Maffeo, Davide
Journal of the Chemical Society, Dalton Transactions, Issue 1
DOI: 10.1039/b105966c

Detailed analysis of the optical absorption and emission spectra of europium(3+) in the trigonal (C3) Eu(DBM)3.H2O system
journal, July 1983

Kirby, Andrew F.; Richardson, F. S.
The Journal of Physical Chemistry, Vol. 87, Issue 14
DOI: 10.1021/j100237a018

Reference materials for fluorescence measurement
journal, January 1988

Eaton, D. F.
Pure and Applied Chemistry, Vol. 60, Issue 7, p. 1107-1114
DOI: 10.1351/pac198860071107

On the determination of the number of water molecules, q, coordinated to europium(III) ions in solution from luminescence decay lifetimes
journal, November 2002

Supkowski, Ronald M.; Horrocks, William DeW.
Inorganica Chimica Acta, Vol. 340
DOI: 10.1016/S0020-1693(02)01022-8

Similar Records in DOE PAGES and OSTI.GOV collections:

An Octadentate Luminescent Eu(III) 1,2-HOPO Chelate with PotentAqueous Stability

Journal Article Moore, Evan G ; Jocher, Christoph J ; Xu, Jide ; ... - Inorganic Chemistry
https://doi.org/10.1021/ic700364t

Full Text Available
New Insights into Structure and Luminescence of Eu ^III and Sm ^III Complexes of the 3,4,3-LI(1,2-HOPO) Ligand

Journal Article Daumann, Lena J. ; Tatum, David S. ; Snyder, Benjamin E. R. ; ... - Journal of the American Chemical Society

We report the preparation and new insight into photophysical properties of luminescent hydroxypyridonate complexes [M^IIIL]^- (M = Eu or Sm) of the versatile 3,4,3-LI(1,2-HOPO) ligand (L). We report the crystal structure of this ligand with EuIII as well as insights into the coordination behavior and geometry in solution by using magnetic circular dichroism. In addition TD-DFT calculations were used to examine the excited states of the two different chromophores present in the 3,4,3-LI(1,2-HOPO) ligand. We find that the Eu^III and Sm^III complexes of this ligand undergo a transformation after in situ preparation to yield complexes with higher quantum yield (QY)more »« less
Cited by 58
https://doi.org/10.1021/ja5116524
Toxic heavy metal – Pb, Cd, Sn – complexation by the octadentate hydroxypyridinonate ligand archetype 3,4,3-LI(1,2-HOPO)

Journal Article Deblonde, Gauthier J. -P. ; Lohrey, Trevor D. ; An, Dahlia D. ; ... - New Journal of Chemistry

The toxicity of heavy metals such as lead (Pb), cadmium (Cd) and tin (Sn) has long been known but accidental exposures of large populations to these elements remain unfortunately a topical issue. Chelating agents against Pb, Cd, or Sn poisoning are still limited to classical ligands such as ethylenediamine tetraacetic acid (EDTA). In this paper, we evaluate the ability of 3,4,3-LI(1,2-HOPO) (L^4-), an octadentate ligand currently under evaluation for actinide decorporation, to bind Pb, Cd and Sn metal ions in aqueous solutions. This ligand forms 1 : 1 complexes with Pb(II), Cd(II) and Sn(IV) as well as bimetallic 2 :more »« less
Cited by 21
https://doi.org/10.1039/c7nj04559j

Full Text Available
Eu(III) Complexes of Octadentate 1-Hydroxy-2-pyridinones: Stability and Improved Photophysical Performance

Journal Article Moore, Evan G ; D'Aleo, Anthony ; Xu, Jide ; ... - Australian Journal of Chemistry

The luminescence properties of lanthanoid ions can be dramatically enhanced by coupling them to antenna ligands that absorb light in the UV-visible and then efficiently transfer the energy to the lanthanoid centre. The synthesis and the complexation of Ln{sup III} cations (Ln = Eu, Gd) for a ligand based on four 1-hydroxy-2-pyridinone (1,2-HOPO) chelators appended to a ligand backbone derived by linking two L-lysine units (3LI-bis-LYS) is described. This octadentate Eu{sup III} complex ([Eu(3LI-bis-LYS-1,2-HOPO)]{sup -}) has been evaluated in terms of its thermodynamic stability, UV-visible absorption and luminescence properties. For this complex, the conditional stability constant (pM) is 19.9, whichmore »« less
https://doi.org/10.1071/CH09314

Full Text Available
Siderophore inspired tetra- and octadentate antenna ligands for luminescent Eu(III) and Tb(III) complexes

Journal Article Daumann, Lena J. ; Werther, Philipp ; Ziegler, Michael J. ; ... - Journal of Inorganic Biochemistry
Cited by 12
https://doi.org/10.1016/j.jinorgbio.2016.01.006

Similar Records

Title: Optimization of the Sensitization Process and Stability of Octadentate Eu(III) 1,2-HOPO Complexes

Citation Formats

Design of Lanthanide Complex Probes for Highly Sensitive Time-Resolved Fluorometric Detection Methods and Its Application to Biochemical, Environmental and Clinical Analyses journal, October 2006

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging journal, January 2014

Substituent Effects on Gd(III)-Based MRI Contrast Agents: Optimizing the Stability and Selectivity of the Complex and the Number of Coordinated Water Molecules1 journal, October 2006

Aryl-Bridged 1-Hydroxypyridin-2-one: Sensitizer Ligands for Eu(III) journal, July 2008

From Antenna to Assay: Lessons Learned in Lanthanide Luminescence journal, April 2009

New Insights into Structure and Luminescence of Eu III and Sm III Complexes of the 3,4,3-LI(1,2-HOPO) Ligand journal, February 2015

Optical Absorption Intensities of Rare-Earth Ions journal, August 1962

Gadolinium(III) 1,2-Hydroxypyridonate-Based Complexes: Toward MRI Contrast Agents of High Relaxivity1 journal, September 2004

The emission spectrum and the radiative lifetime of Eu3+ in luminescent lanthanide complexes journal, March 2002

New Lanthanide Complexes with Antioxidant Activity journal, July 2008

50th anniversary of the Judd–Ofelt theory: An experimentalist's view of the formalism and its application journal, April 2013

Synthesis, characterization, and antioxidative activity of new vitamin B6 triethanolamine rare earth (III) complexes journal, November 1993

Highly Luminescent and Stable Hydroxypyridinonate Complexes: A Step Towards New Curium Decontamination Strategies journal, July 2014

Modulating the Photophysical Properties of Azamacrocyclic Europium Complexes with Charge-Transfer Antenna Chromophores journal, June 2011

Lanthanide Luminescence for Biomedical Analyses and Imaging journal, May 2010

Intensities of Crystal Spectra of Rare‐Earth Ions journal, August 1962

NMR Structure Determination of Protein−Ligand Complexes by Lanthanide Labeling journal, March 2007

Primer on gadolinium chemistry journal, December 2009

Correlation between the lowest triplet state energy level of the ligand and lanthanide(III) luminescence quantum yield journal, September 1997

Of Folding and Function: Understanding Active-Site Context through Metalloenzyme Design journal, December 2006

Diverse Solid-State and Solution Structures within a Series of Hexaamine Dicopper(II) Complexes journal, March 2001

Development of Decorporation Agents for the Actinides journal, October 1998

Toward Optimized High-Relaxivity MRI Agents: The Effect of Ligand Basicity on the Thermodynamic Stability of Hexadentate Hydroxypyridonate/Catecholate Gadolinium(III) Complexes journal, August 2003

Lanthanide Luminescent Bioprobes (LLBs) journal, February 2009

Lanthanide-based luminescence probes and time-resolved luminescence bioassays journal, May 2006

Sequence-Specific and Stereospecific Assignment of Methyl Groups Using Paramagnetic Lanthanides journal, November 2007

Characterization, HPLC method development and impurity identification for 3,4,3-LI(1,2-HOPO), a potent actinide chelator for radionuclide decorporation journal, January 2015

Intriguing aspects of lanthanide luminescence journal, January 2013

Very bright europium complexes that stain cellular mitochondria journal, January 2013

Efficient Sensitization of Europium, Ytterbium, and Neodymium Functionalized Tris-Dipicolinate Lanthanide Complexes through Tunable Charge-Transfer Excited States journal, November 2008

“Cymothoe sangaris”: An Extremely Stable and Highly Luminescent 1,2-Hydroxypyridinonate Chelate of Eu(III) July 2006

Luminescent Lanthanide Cryptates: from the Bench to the Bedside journal, December 2013

LANCE™: Homogeneous Assay Platform for HTS journal, December 1999

A Time-Resolved Fluorescence Immunoassay (DELFIA) Increases the Sensitivity of Antigen-Driven Cytokine Detection journal, January 2003

HTRF® Technology journal, December 1999

Highly Luminescent Lanthanide Complexes of 1-Hydroxy-2-pyridinones journal, April 2008

An Octadentate Luminescent Eu(III) 1,2-HOPO Chelate with Potent Aqueous Stability journal, July 2007

Water-Soluble 2-Hydroxyisophthalamides for Sensitization of Lanthanide Luminescence journal, September 2008

Alternative Chelator for 89 Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO) journal, December 2013

A Water-Soluble Pybox Derivative and Its Highly Luminescent Lanthanide Ion Complexes journal, April 2012

Intramolecular sensitisation of lanthanide(iii) luminescence by acetophenone-containing ligands: the critical effect of para-substituents and solvent journal, November 2001

Detailed analysis of the optical absorption and emission spectra of europium(3+) in the trigonal (C3) Eu(DBM)3.H2O system journal, July 1983

Reference materials for fluorescence measurement journal, January 1988

On the determination of the number of water molecules, q, coordinated to europium(III) ions in solution from luminescence decay lifetimes journal, November 2002

Design of Lanthanide Complex Probes for Highly Sensitive Time-Resolved Fluorometric Detection Methods and Its Application to Biochemical, Environmental and Clinical Analyses
journal, October 2006

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging
journal, January 2014

Substituent Effects on Gd(III)-Based MRI Contrast Agents: Optimizing the Stability and Selectivity of the Complex and the Number of Coordinated Water Molecules¹
journal, October 2006

Aryl-Bridged 1-Hydroxypyridin-2-one: Sensitizer Ligands for Eu(III)
journal, July 2008

From Antenna to Assay: Lessons Learned in Lanthanide Luminescence
journal, April 2009

New Insights into Structure and Luminescence of Eu ^III and Sm ^III Complexes of the 3,4,3-LI(1,2-HOPO) Ligand
journal, February 2015

Optical Absorption Intensities of Rare-Earth Ions
journal, August 1962

Gadolinium(III) 1,2-Hydroxypyridonate-Based Complexes: Toward MRI Contrast Agents of High Relaxivity¹
journal, September 2004

The emission spectrum and the radiative lifetime of Eu3+ in luminescent lanthanide complexes
journal, March 2002

New Lanthanide Complexes with Antioxidant Activity
journal, July 2008

50th anniversary of the Judd–Ofelt theory: An experimentalist's view of the formalism and its application
journal, April 2013

Synthesis, characterization, and antioxidative activity of new vitamin B6 triethanolamine rare earth (III) complexes
journal, November 1993

Highly Luminescent and Stable Hydroxypyridinonate Complexes: A Step Towards New Curium Decontamination Strategies
journal, July 2014

Modulating the Photophysical Properties of Azamacrocyclic Europium Complexes with Charge-Transfer Antenna Chromophores
journal, June 2011

Lanthanide Luminescence for Biomedical Analyses and Imaging
journal, May 2010

Intensities of Crystal Spectra of Rare‐Earth Ions
journal, August 1962

NMR Structure Determination of Protein−Ligand Complexes by Lanthanide Labeling
journal, March 2007

Primer on gadolinium chemistry
journal, December 2009

Correlation between the lowest triplet state energy level of the ligand and lanthanide(III) luminescence quantum yield
journal, September 1997

Of Folding and Function: Understanding Active-Site Context through Metalloenzyme Design
journal, December 2006

Diverse Solid-State and Solution Structures within a Series of Hexaamine Dicopper(II) Complexes
journal, March 2001

Development of Decorporation Agents for the Actinides
journal, October 1998

Toward Optimized High-Relaxivity MRI Agents: The Effect of Ligand Basicity on the Thermodynamic Stability of Hexadentate Hydroxypyridonate/Catecholate Gadolinium(III) Complexes
journal, August 2003

Lanthanide Luminescent Bioprobes (LLBs)
journal, February 2009

Lanthanide-based luminescence probes and time-resolved luminescence bioassays
journal, May 2006

Sequence-Specific and Stereospecific Assignment of Methyl Groups Using Paramagnetic Lanthanides
journal, November 2007

Characterization, HPLC method development and impurity identification for 3,4,3-LI(1,2-HOPO), a potent actinide chelator for radionuclide decorporation
journal, January 2015

Intriguing aspects of lanthanide luminescence
journal, January 2013

Very bright europium complexes that stain cellular mitochondria
journal, January 2013

Efficient Sensitization of Europium, Ytterbium, and Neodymium Functionalized Tris-Dipicolinate Lanthanide Complexes through Tunable Charge-Transfer Excited States
journal, November 2008

“Cymothoe sangaris”: An Extremely Stable and Highly Luminescent 1,2-Hydroxypyridinonate Chelate of Eu(III)
July 2006

Luminescent Lanthanide Cryptates: from the Bench to the Bedside
journal, December 2013

LANCE™: Homogeneous Assay Platform for HTS
journal, December 1999

A Time-Resolved Fluorescence Immunoassay (DELFIA) Increases the Sensitivity of Antigen-Driven Cytokine Detection
journal, January 2003

HTRF® Technology
journal, December 1999

Highly Luminescent Lanthanide Complexes of 1-Hydroxy-2-pyridinones
journal, April 2008

An Octadentate Luminescent Eu(III) 1,2-HOPO Chelate with Potent Aqueous Stability
journal, July 2007

Water-Soluble 2-Hydroxyisophthalamides for Sensitization of Lanthanide Luminescence
journal, September 2008

Alternative Chelator for ⁸⁹ Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO)
journal, December 2013

A Water-Soluble Pybox Derivative and Its Highly Luminescent Lanthanide Ion Complexes
journal, April 2012

Intramolecular sensitisation of lanthanide(iii) luminescence by acetophenone-containing ligands: the critical effect of para-substituents and solvent
journal, November 2001

Detailed analysis of the optical absorption and emission spectra of europium(3+) in the trigonal (C3) Eu(DBM)3.H2O system
journal, July 1983

Reference materials for fluorescence measurement
journal, January 1988

On the determination of the number of water molecules, q, coordinated to europium(III) ions in solution from luminescence decay lifetimes
journal, November 2002